BRCA1 associated RING domain 1.

BLM RecQ like helicase.

BRCA1 associated RING domain 1.

Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]

BRCA1 associated RING domain 1.

BRCA1 interacting protein C-terminal helicase 1.

BRCA1 associated RING domain 1.

Serine/threonine-protein kinase Chk1 isoform X2; Belongs to the protein kinase superfamily.

BRCA1 associated RING domain 1.

DNA replication helicase/nuclease 2.

BRCA1 associated RING domain 1.

Exonuclease 1.

BRCA1 associated RING domain 1.

Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.

BRCA1 associated RING domain 1.

Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.

BRCA1 associated RING domain 1.

Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.

BRCA1 associated RING domain 1.

Zinc-hook domain-containing protein.

BRCA1 associated RING domain 1.

DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]

BRCA1 associated RING domain 1.

RAD51 paralog B.

BRCA1 associated RING domain 1.

RAD51 paralog C.

BRCA1 associated RING domain 1.

RB binding protein 8, endonuclease.

BRCA1 associated RING domain 1.

RecQ mediated genome instability 1.

BRCA1 associated RING domain 1.

RecQ-mediated genome instability protein 2.

BRCA1 associated RING domain 1.

DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.

BRCA1 associated RING domain 1.

WRN RecQ like helicase.

BRCA1 associated RING domain 1.

X-ray repair cross complementing 2.

BLM RecQ like helicase.

BRCA1 associated RING domain 1.