STRINGSTRING
FURIN FURIN KRT82 KRT82 KRT75 KRT75 LOC100523670 LOC100523670 KRT85 KRT85 KRT84 KRT84 KRT5 KRT5 KRT72 KRT72 KRT1 KRT1 DSP DSP CTRC CTRC DSC1 DSC1 PCSK6 PCSK6 PPL PPL LIPM LIPM CAPN1 CAPN1 CASP14 CASP14 SPINK9 SPINK9 EVPL EVPL JUP JUP KRT35 KRT35 KRT32 KRT32 KRT34 KRT34 KRT33A KRT33A KRT39 KRT39 KRT28 KRT28 KRT27 KRT27 KRT26 KRT26 KRT25 KRT25 KRT74 KRT74 DSG4 DSG4 KRT24 KRT24 DSG1 DSG1 KRT10 KRT10 KRT23 KRT23 LOC100621639 LOC100621639 CAPNS1 CAPNS1 SPINK5 SPINK5 PRSS8 PRSS8 CELA2A CELA2A KRT18 KRT18 PKP2 PKP2 A0A5G2QWB6_PIG A0A5G2QWB6_PIG KRT36 KRT36 LOC100621844 LOC100621844 KRT15 KRT15 LOC100515166 LOC100515166 DSG3 DSG3 LOC100516036 LOC100516036 KRT31 KRT31 RPTN RPTN TGM1 TGM1 LOC106507258 LOC106507258 KLK8 KLK8 KRT12 KRT12 PKP3 PKP3 KRT4 KRT4 PKP1 PKP1 KLK13 KLK13 KLK5 KLK5 LIPN LIPN DSC2 DSC2 KRT79 KRT79 KRT71 KRT71 KRT80 KRT80 SPINK6 SPINK6 KAZN KAZN KRT7 KRT7 PKP4 PKP4 ST14 ST14 KRT8 KRT8 KRT40 KRT40 LOC100523123 LOC100523123 DSG2 DSG2 KRT73 KRT73 PERP PERP KRT78 KRT78 LOC102162785 LOC102162785 KRT77 KRT77 KLK14 KLK14 KRT2 KRT2 KRT14 KRT14 KLK12 KLK12 KRT3 KRT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (797 aa)
KRT82Keratin 82; Belongs to the intermediate filament family. (513 aa)
KRT75Keratin 75; Belongs to the intermediate filament family. (550 aa)
LOC100523670IF rod domain-containing protein; Belongs to the intermediate filament family. (493 aa)
KRT85Keratin 85; Belongs to the intermediate filament family. (506 aa)
KRT84Keratin 84; Belongs to the intermediate filament family. (593 aa)
KRT5Keratin 5; Belongs to the intermediate filament family. (602 aa)
KRT72Keratin 72; Belongs to the intermediate filament family. (508 aa)
KRT1Keratin 1; Belongs to the intermediate filament family. (624 aa)
DSPDesmoplakin. (2883 aa)
CTRCChymotrypsin-C; Belongs to the peptidase S1 family. (268 aa)
DSC1Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (897 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6 isoform PACE4-AI preproprotein; Belongs to the peptidase S8 family. (965 aa)
PPLPeriplakin. (1925 aa)
LIPMLipase; Belongs to the AB hydrolase superfamily. Lipase family. (423 aa)
CAPN1Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. (775 aa)
CASP14Caspase 14, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (242 aa)
SPINK9Serine peptidase inhibitor, Kazal type 9. (84 aa)
EVPLEnvoplakin. (1886 aa)
JUPJunction plakoglobin; Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E- cadherin/catenin adhes [...] (744 aa)
KRT35Keratin 35; Belongs to the intermediate filament family. (455 aa)
KRT32Keratin 32; Belongs to the intermediate filament family. (387 aa)
KRT34IF rod domain-containing protein; Belongs to the intermediate filament family. (391 aa)
KRT33AIF rod domain-containing protein; Belongs to the intermediate filament family. (403 aa)
KRT39Keratin 39; Belongs to the intermediate filament family. (490 aa)
KRT28Keratin 28; Belongs to the intermediate filament family. (463 aa)
KRT27IF rod domain-containing protein; Belongs to the intermediate filament family. (460 aa)
KRT26Keratin 26; Belongs to the intermediate filament family. (469 aa)
KRT25Keratin 25; Belongs to the intermediate filament family. (452 aa)
KRT74IF rod domain-containing protein; Belongs to the intermediate filament family. (531 aa)
DSG4Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1042 aa)
KRT24Keratin 24; Belongs to the intermediate filament family. (537 aa)
DSG1Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (By similarity). (1045 aa)
KRT10Keratin 10; Belongs to the intermediate filament family. (573 aa)
KRT23Keratin 23; Belongs to the intermediate filament family. (416 aa)
LOC100621639IF rod domain-containing protein; Belongs to the intermediate filament family. (407 aa)
CAPNS1Calpain small subunit 1; Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. (273 aa)
SPINK5Serine peptidase inhibitor, Kazal type 5. (1023 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (344 aa)
CELA2AChymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. (287 aa)
KRT18Keratin 18; Belongs to the intermediate filament family. (423 aa)
PKP2Plakophilin 2. (837 aa)
A0A5G2QWB6_PIGUncharacterized protein. (979 aa)
KRT36Keratin 36; Belongs to the intermediate filament family. (459 aa)
LOC100621844IF rod domain-containing protein; Belongs to the intermediate filament family. (488 aa)
KRT15Keratin 15; Belongs to the intermediate filament family. (526 aa)
LOC100515166IF rod domain-containing protein; Belongs to the intermediate filament family. (454 aa)
DSG3Desmoglein 3. (989 aa)
LOC100516036IF rod domain-containing protein; Belongs to the intermediate filament family. (422 aa)
KRT31IF rod domain-containing protein; Belongs to the intermediate filament family. (414 aa)
RPTNEF-hand domain-containing protein. (602 aa)
TGM1Protein-glutamine gamma-glutamyltransferase K. (826 aa)
LOC106507258IF rod domain-containing protein; Belongs to the intermediate filament family. (483 aa)
KLK8Kallikrein related peptidase 8; Belongs to the peptidase S1 family. (259 aa)
KRT12Keratin 12; Belongs to the intermediate filament family. (519 aa)
PKP3Plakophilin 3. (1145 aa)
KRT4Keratin 4; Belongs to the intermediate filament family. (533 aa)
PKP1Plakophilin-1 isoform 1a. (727 aa)
KLK13Kallikrein related peptidase 13; Belongs to the peptidase S1 family. (278 aa)
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (295 aa)
LIPNLipase; Belongs to the AB hydrolase superfamily. Lipase family. (398 aa)
DSC2Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (911 aa)
KRT79Keratin 79; Belongs to the intermediate filament family. (543 aa)
KRT71Keratin 71; Belongs to the intermediate filament family. (525 aa)
KRT80Keratin, type II cytoskeletal 80 isoform K80; Belongs to the intermediate filament family. (452 aa)
SPINK6Serine peptidase inhibitor, Kazal type 6. (80 aa)
KAZNKazrin, periplakin interacting protein. (864 aa)
KRT7Keratin 7; Belongs to the intermediate filament family. (468 aa)
PKP4Plakophilin 4. (1234 aa)
ST14Suppressor of tumorigenicity 14 protein. (856 aa)
KRT8Keratin, type II cytoskeletal 8 isoform 2; Belongs to the intermediate filament family. (461 aa)
KRT40Keratin 40; Belongs to the intermediate filament family. (427 aa)
LOC100523123IF rod domain-containing protein; Belongs to the intermediate filament family. (496 aa)
DSG2Desmoglein 2. (1127 aa)
KRT73Keratin 73; Belongs to the intermediate filament family. (540 aa)
PERPUncharacterized protein. (193 aa)
KRT78Keratin 78; Belongs to the intermediate filament family. (576 aa)
LOC102162785IF rod domain-containing protein; Belongs to the intermediate filament family. (338 aa)
KRT77Keratin 77; Belongs to the intermediate filament family. (591 aa)
KLK14Kallikrein related peptidase 14; Belongs to the peptidase S1 family. (252 aa)
KRT2IF rod domain-containing protein; Belongs to the intermediate filament family. (639 aa)
KRT14Keratin 14; Belongs to the intermediate filament family. (515 aa)
KLK12Kallikrein related peptidase 12; Belongs to the peptidase S1 family. (248 aa)
KRT3Keratin 3; Belongs to the intermediate filament family. (643 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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