STRINGSTRING
PIK3R6 PIK3R6 A2M A2M GNB3 GNB3 CSK CSK ISLR ISLR VTI1B VTI1B PLCG2 PLCG2 PRKCG PRKCG PDPN PDPN FYN FYN THBS1 THBS1 RASGRP1 RASGRP1 PRKCH PRKCH TOR4A TOR4A YWHAZ YWHAZ LYN LYN TAGLN2 TAGLN2 GNAI3 GNAI3 PDGFA PDGFA GNB2 GNB2 GNG13 GNG13 ADRA2B ADRA2B PRKCE PRKCE SOS1 SOS1 TRPC3 TRPC3 ANXA5 ANXA5 MMRN1 MMRN1 VCL VCL ADRA2A ADRA2A NHLRC2 NHLRC2 LOC100524517 LOC100524517 SCCPDH SCCPDH PRKCQ PRKCQ GNAI2 GNAI2 TEX264 TEX264 P2RY12 P2RY12 P2RY1 P2RY1 HRG HRG APP APP VEGFD VEGFD DGKK DGKK SYTL4 SYTL4 DAGLA DAGLA SERPING1 SERPING1 CFD CFD GNA15 GNA15 PCYOX1L PCYOX1L ENDOD1 ENDOD1 GNGT1 GNGT1 COL1A2 COL1A2 HGF HGF GNAT3 GNAT3 GNAI1 GNAI1 VEGFC VEGFC RAPGEF4 RAPGEF4 FN1 FN1 AAMP AAMP DGKD DGKD GTPBP2 GTPBP2 LCP2 LCP2 GRB2 GRB2 PRKCA PRKCA DGKE DGKE GP1BA GP1BA LEFTY2 LEFTY2 RAPGEF3 RAPGEF3 ECM1 ECM1 ADRA2C ADRA2C ABHD12 ABHD12 GNG2 GNG2 DGKG DGKG SELENOP SELENOP FGG FGG SRGN SRGN PIK3R1 PIK3R1 ACTN1 ACTN1 GNG8 GNG8 CLEC1B CLEC1B SERPINE1 SERPINE1 SOD1 SOD1 GP6 GP6 CD109 CD109 TMSB4X TMSB4X SHC1 SHC1 GP1BB GP1BB APOH APOH F2RL3 F2RL3 GP5 GP5 CD63 CD63 CDC42 CDC42 SRC SRC TGFB1 TGFB1 TGFB3 TGFB3 SPNS1 SPNS1 GNB5 GNB5 LHFPL2 LHFPL2 GNG3 GNG3 ARRB1 ARRB1 VAV1 VAV1 SERPINA4 SERPINA4 WDR1 WDR1 RAB27B RAB27B CRK CRK MPIG6B MPIG6B F2R F2R MGLL MGLL PDPK1 PDPK1 GNAQ GNAQ RAP1B RAP1B APBB1IP APBB1IP CYB5R1 CYB5R1 PTPN6 PTPN6 GNB4 GNB4 TIMP3 TIMP3 TBXA2R TBXA2R DGKZ DGKZ PTPN1 PTPN1 ABHD6 ABHD6 CTSW CTSW APLP2 APLP2 GP9 GP9 PROS1 PROS1 ACTN4 ACTN4 GNA13 GNA13 ACTG1 ACTG1 LY6G6D LY6G6D TLN1 TLN1 MAPK1 MAPK1 A0A287ACS9_PIG A0A287ACS9_PIG PDGFB PDGFB CLEC3B CLEC3B LOC110255211 LOC110255211 DGKI DGKI RASGRP2 RASGRP2 LCK LCK DGKA DGKA GNA12 GNA12 STX4 STX4 GNA14 GNA14 SCG3 SCG3 LOC100621494 LOC100621494 PECAM1 PECAM1 RHOA RHOA HABP4 HABP4 DGKH DGKH FLNA FLNA GNB1 GNB1 FAM3C FAM3C GAS6 GAS6 FAM49B FAM49B F2RL2 F2RL2 BCAR1 BCAR1 RAP1A RAP1A RHOG RHOG DGKB DGKB RARRES2 RARRES2 CLU CLU LAMP2 LAMP2 PIK3CB PIK3CB PIK3CA PIK3CA SERPINF2 SERPINF2 LOC100511937 LOC100511937 ABCC4 ABCC4 PRKCD PRKCD DAGLB DAGLB ALDOA ALDOA SERPINA3-2 SERPINA3-2 IGF2 IGF2 ITPR3 ITPR3 MAPK3 MAPK3 ITIH3 ITIH3 PLA2G4A PLA2G4A CDC37L1 CDC37L1 FERMT3 FERMT3 APOOL APOOL PIK3R2 PIK3R2 ARRB2 ARRB2 RAC1 RAC1 DGKQ DGKQ CHID1 CHID1 ITPR1 ITPR1 PTPN11 PTPN11 MAPK14 MAPK14 ACTN2 ACTN2 PHACTR2 PHACTR2 COL1A1 COL1A1 PCDH7 PCDH7 TRPC7 TRPC7 VAV3 VAV3 PLEK PLEK RHOB RHOB KNG1 KNG1 QSOX1 QSOX1 MANF MANF LOC100621431 LOC100621431 TMX3 TMX3 RAC2 RAC2 ORM1 ORM1 OLA1 OLA1 BRPF3 BRPF3 VAV2 VAV2 F13A1 F13A1 TRPC6 TRPC6 TUBA4A TUBA4A PPBP PPBP GNG10 GNG10 ITGB3 ITGB3 SPARC SPARC SELP SELP LGALS3BP LGALS3BP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (942 aa)
A2MAlpha-2-macroglobulin. (1504 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. (340 aa)
CSKTyrosine-protein kinase. (474 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (436 aa)
VTI1Bt-SNARE coiled-coil homology domain-containing protein. (232 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (759 aa)
PDPNUncharacterized protein. (159 aa)
FYNTyrosine-protein kinase Fyn; Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through [...] (537 aa)
THBS1Uncharacterized protein. (1170 aa)
RASGRP1RAS guanyl releasing protein 1. (797 aa)
PRKCHProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
TOR4ATorsin family 4 member A. (415 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (260 aa)
LYNTyrosine-protein kinase. (512 aa)
TAGLN2Transgelin; Belongs to the calponin family. (213 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (286 aa)
GNB2G protein subunit beta 2. (340 aa)
GNG13G protein subunit gamma 13. (67 aa)
ADRA2BAlpha-2B adrenergic receptor. (446 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1369 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
ANXA5Annexin. (321 aa)
MMRN1Multimerin 1. (1220 aa)
VCLVinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family. (1135 aa)
ADRA2AAlpha-2A adrenergic receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. (465 aa)
NHLRC2NHL repeat-containing protein 2. (725 aa)
LOC100524517Left-right determination factor. (373 aa)
SCCPDHSacchrp_dh_NADP domain-containing protein. (429 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (732 aa)
GNAI2G protein subunit alpha i2. (355 aa)
TEX264Testis expressed 264, ER-phagy receptor. (284 aa)
P2RY12Purinergic receptor P2Y12. (339 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
HRGUncharacterized protein. (561 aa)
APPGamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (756 aa)
VEGFDVascular endothelial growth factor D preproprotein; Belongs to the PDGF/VEGF growth factor family. (354 aa)
DGKKDiacylglycerol kinase. (1266 aa)
SYTL4Synaptotagmin like 4. (721 aa)
DAGLADiacylglycerol lipase alpha. (1058 aa)
SERPING1Plasma protease C1 inhibitor isoform X1; Belongs to the serpin family. (491 aa)
CFDComplement factor D; Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway (By similarity). (259 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (374 aa)
PCYOX1LPrenylcysteine oxidase 1 like. (457 aa)
ENDOD1Endonuclease domain containing 1. (500 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
COL1A2Fibrillar collagen NC1 domain-containing protein. (1135 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. (354 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (995 aa)
FN1Fibronectin 1. (2462 aa)
AAMPAngio associated migratory cell protein. (388 aa)
DGKDDiacylglycerol kinase. (1244 aa)
GTPBP2GTP binding protein 2. (694 aa)
LCP2Lymphocyte cytosolic protein 2. (532 aa)
GRB2Growth factor receptor-bound protein 2 isoform 1. (217 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
DGKEDiacylglycerol kinase. (566 aa)
GP1BAPlatelet glycoprotein Ib alpha polypeptide. (627 aa)
LEFTY2Left-right determination factor. (366 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3 isoform a. (923 aa)
ECM1Extracellular matrix protein 1. (559 aa)
ADRA2CAdrenoceptor alpha 2C. (460 aa)
ABHD12Monoacylglycerol lipase ABHD12 isoform a. (396 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (248 aa)
DGKGDiacylglycerol kinase. (791 aa)
SELENOPUncharacterized protein. (390 aa)
FGGFibrinogen gamma chain. (454 aa)
SRGNSerglycin. (152 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (766 aa)
ACTN1Uncharacterized protein. (888 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
CLEC1BC-type lectin domain family 1 member B. (226 aa)
SERPINE1Plasminogen activator inhibitor 1; Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase- type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. I [...] (401 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (155 aa)
GP6Ig-like domain-containing protein. (319 aa)
CD109CD109 antigen isoform 1 preproprotein. (1449 aa)
TMSB4XHematopoietic system regulatory peptide; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization; Belongs to the thymosin beta family. (44 aa)
SHC1SHC adaptor protein 1. (583 aa)
GP1BBPlatelet glycoprotein Ib beta chain. (203 aa)
APOHBeta-2-glycoprotein 1. (345 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (382 aa)
GP5Glycoprotein V platelet. (569 aa)
CD63Tetraspanin. (237 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
SRCTyrosine-protein kinase. (559 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
TGFB3Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. Transforming growth factor beta-3: Multifunctional protein that regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi appa [...] (456 aa)
SPNS1MFS domain-containing protein. (476 aa)
GNB5G protein subunit beta 5. (420 aa)
LHFPL2LHFPL tetraspan subfamily member 2 protein isoform X1. (228 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (240 aa)
ARRB1Arrestin beta 1. (607 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
SERPINA4Serpin family A member 4; Belongs to the serpin family. (371 aa)
WDR1WD repeat-containing protein 1 isoform 1. (606 aa)
RAB27BRAB27B, member RAS oncogene family. (247 aa)
CRKCRK proto-oncogene, adaptor protein. (385 aa)
MPIG6BIg-like domain-containing protein. (328 aa)
F2RG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (427 aa)
MGLLMonoglyceride lipase. (456 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (668 aa)
GNAQGuanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. (359 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (688 aa)
CYB5R1Cytochrome b5 reductase 1. (487 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (612 aa)
GNB4G protein subunit beta 4. (340 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
TBXA2RThromboxane A2 receptor. (343 aa)
DGKZDiacylglycerol kinase. (1144 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
CTSWCathepsin W; Belongs to the peptidase C1 family. (368 aa)
APLP2Amyloid beta precursor like protein 2. (770 aa)
GP9Glycoprotein IX platelet. (173 aa)
PROS1Protein S. (702 aa)
ACTN4Actinin alpha 4. (1160 aa)
GNA13G protein subunit alpha 13. (377 aa)
ACTG1Actin gamma 1. (381 aa)
LY6G6DIg-like domain-containing protein. (445 aa)
TLN1Talin 1. (2558 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (568 aa)
A0A287ACS9_PIGGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa)
CLEC3BC-type lectin domain family 3 member B. (202 aa)
LOC110255211Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (125 aa)
DGKIDiacylglycerol kinase. (1110 aa)
RASGRP2Uncharacterized protein. (881 aa)
LCKTyrosine-protein kinase. (520 aa)
DGKADiacylglycerol kinase alpha; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. (785 aa)
GNA12G protein subunit alpha 12. (382 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (338 aa)
GNA14Guanine nucleotide-binding protein alpha 14. (355 aa)
SCG3Secretogranin III. (549 aa)
LOC100621494SERPIN domain-containing protein; Belongs to the serpin family. (407 aa)
PECAM1Platelet endothelial cell adhesion molecule; Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutr [...] (740 aa)
RHOATransforming protein RhoA isoform 1. (193 aa)
HABP4Intracellular hyaluronan-binding protein 4. (418 aa)
DGKHDiacylglycerol kinase. (1222 aa)
FLNAFilamin A. (2897 aa)
GNB1G protein subunit beta 1. (395 aa)
FAM3CFamily with sequence similarity 3 member C. (227 aa)
GAS6Uncharacterized protein. (682 aa)
FAM49BUncharacterized protein. (468 aa)
F2RL2Coagulation factor II thrombin receptor like 2; Belongs to the G-protein coupled receptor 1 family. (378 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (887 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
RHOGUncharacterized protein. (394 aa)
DGKBDiacylglycerol kinase. (802 aa)
RARRES2Retinoic acid receptor responder 2. (177 aa)
CLUClusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] (472 aa)
LAMP2Lysosome-associated membrane glycoprotein 2 isoform A. (411 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SERPINF2Alpha-2-antiplasmin isoform X2; Belongs to the serpin family. (563 aa)
LOC100511937Uncharacterized protein. (532 aa)
ABCC4Multidrug resistance-associated protein 4 isoform X1. (1325 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (723 aa)
DAGLBDiacylglycerol lipase beta. (691 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (532 aa)
SERPINA3-2SERPIN domain-containing protein; Belongs to the serpin family. (473 aa)
IGF2Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...] (583 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2680 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
ITIH3Inter-alpha-trypsin inhibitor heavy chain 3. (907 aa)
PLA2G4APhospholipase A2. (758 aa)
CDC37L1Cell division cycle 37 like 1. (339 aa)
FERMT3Fermitin family member 3. (667 aa)
APOOLMICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (268 aa)
PIK3R2Uncharacterized protein. (772 aa)
ARRB2Arrestin beta 2. (493 aa)
RAC1Rac family small GTPase 1. (186 aa)
DGKQDiacylglycerol kinase. (987 aa)
CHID1Chitinase domain containing 1. (511 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2759 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ACTN2Uncharacterized protein. (933 aa)
PHACTR2Phosphatase and actin regulator. (759 aa)
COL1A1Collagen type I alpha 1 chain. (1477 aa)
PCDH7Uncharacterized protein. (1246 aa)
TRPC7Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
VAV3Vav guanine nucleotide exchange factor 3. (874 aa)
PLEKPleckstrin. (408 aa)
RHOBRho-related GTP-binding protein RhoB. (196 aa)
KNG1Kininogen 1. (630 aa)
QSOX1Sulfhydryl oxidase. (742 aa)
MANFUncharacterized protein. (189 aa)
LOC100621431Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (234 aa)
TMX3Thioredoxin related transmembrane protein 3. (454 aa)
RAC2Rac family small GTPase 2. (217 aa)
ORM1Lipocln_cytosolic_FA-bd_dom domain-containing protein. (212 aa)
OLA1Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (413 aa)
BRPF3Bromodomain and PHD finger containing 3. (1150 aa)
VAV2Vav guanine nucleotide exchange factor 2. (879 aa)
F13A1Coagulation factor XIII A chain. (774 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (939 aa)
TUBA4ATubulin alpha 4a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (618 aa)
PPBPPlatelet basic protein; Chemoattractant factor for neutrophils. (159 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (835 aa)
SPARCSPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity); Belongs to the SPARC family. (331 aa)
SELPUncharacterized protein. (671 aa)
LGALS3BPGalectin 3 binding protein. (551 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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