STRINGSTRING
SNAP25 SNAP25 SLC6A11 SLC6A11 CPLX1 CPLX1 RIMS1 RIMS1 VAMP2 VAMP2 SYT1 SYT1 ALDH5A1 ALDH5A1 SLC32A1 SLC32A1 STX1A STX1A GAD2 GAD2 RAB3A RAB3A SLC6A13 SLC6A13 SLC6A1 SLC6A1 ABAT ABAT HSPA8 HSPA8 STXBP1 STXBP1 GAD1 GAD1 SLC6A12 SLC6A12 DNAJC5 DNAJC5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
SLC6A11Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (631 aa)
CPLX1Complexin 1. (133 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1684 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (189 aa)
SYT1Synaptotagmin 1. (379 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (535 aa)
SLC32A1Vesicular inhibitory amino acid transporter. (526 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (295 aa)
GAD2Glutamate decarboxylase 2; Catalyzes the production of GABA. (584 aa)
RAB3ARas-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] (254 aa)
SLC6A13Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (600 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (605 aa)
ABAT4-aminobutyrate aminotransferase, mitochondrial; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (520 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (680 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (609 aa)
GAD1Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. (728 aa)
SLC6A12Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (629 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (248 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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