Your Input: | |
| | DCAF4 | WD_REPEATS_REGION domain-containing protein. (526 aa) |
| | CUL9 | Cullin 9; Belongs to the cullin family. (2582 aa) |
| | DCUN1D5 | DCN1-like protein. (237 aa) |
| | ANKRD9 | Uncharacterized protein. (360 aa) |
| | FBXW8 | F-box and WD repeat domain containing 8. (596 aa) |
| | CDRT1 | WD_REPEATS_REGION domain-containing protein. (1077 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (204 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (733 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha isoform 1. (824 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | ASB13 | Ankyrin repeat and SOCS box containing 13. (331 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (108 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (351 aa) |
| | KLHL3 | Kelch like family member 3. (601 aa) |
| | SPSB3 | SplA/ryanodine receptor domain and SOCS box containing 3. (358 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (229 aa) |
| | NPLOC4 | NPL4 homolog, ubiquitin recognition factor. (782 aa) |
| | SPSB4 | SplA/ryanodine receptor domain and SOCS box containing 4. (272 aa) |
| | OBSL1 | Obscurin-like protein 1 isoform X2. (1896 aa) |
| | ASB14 | Ankyrin repeat and SOCS box protein 14 isoform 1. (584 aa) |
| | FBXO30 | F-box protein 30. (949 aa) |
| | FBXO17 | F-box protein 17. (295 aa) |
| | KBTBD6 | Kelch repeat and BTB domain-containing protein 6. (695 aa) |
| | ASB12 | Ankyrin repeat and SOCS box containing 12. (318 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (481 aa) |
| | DCAF5 | DDB1 and CUL4 associated factor 5. (947 aa) |
| | KEAP1 | Kelch-like ECH-associated protein 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination. KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine [...] (624 aa) |
| | FBXO32 | F-box only protein 32; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity). (425 aa) |
| | DCAF7 | DDB1 and CUL4 associated factor 7. (340 aa) |
| | DCAF16 | DDB1 and CUL4 associated factor 16. (172 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) |
| | UBE2M | Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (215 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | FBXO22 | F-box only protein 22 isoform a. (404 aa) |
| | CCDC8 | Coiled-coil domain-containing protein 8. (471 aa) |
| | PSMB10 | Proteasome subunit beta. (296 aa) |
| | PSMA7 | Proteasome subunit alpha type. (267 aa) |
| | FBXO6 | Uncharacterized protein. (282 aa) |
| | COMMD8 | COMM domain containing 8. (215 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | COPS3 | COP9 signalosome subunit 3. (426 aa) |
| | COMMD9 | COMM domain containing 9. (197 aa) |
| | GAN | Gigaxonin. (597 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 isoform 1. (504 aa) |
| | UBE2F | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (250 aa) |
| | KLHL21 | Kelch like family member 21. (598 aa) |
| | COMMD4 | COMM domain containing 4. (198 aa) |
| | UBC | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (837 aa) |
| | PSMA2 | Proteasome endopeptidase complex. (243 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (656 aa) |
| | PSMC5 | 26S proteasome regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (435 aa) |
| | FBXL20 | F-box and leucine rich repeat protein 20. (456 aa) |
| | UBD | Uncharacterized protein. (161 aa) |
| | PSMA4 | Proteasome subunit alpha type. (281 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PSMA3 | Proteasome subunit alpha type. (275 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (419 aa) |
| | FBXO31 | F-box only protein 31 isoform X1. (566 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (712 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (629 aa) |
| | FBXO11 | F-box protein 11. (946 aa) |
| | DCUN1D4 | DCN1-like protein. (423 aa) |
| | FBXL18 | F-box and leucine rich repeat protein 18. (735 aa) |
| | ASB7 | Ankyrin repeat and SOCS box containing 7. (360 aa) |
| | FBXO4 | F-box only protein 4. (387 aa) |
| | ELOC | Elongin C; Belongs to the SKP1 family. (139 aa) |
| | KCTD7 | Potassium channel tetramerization domain containing 7. (305 aa) |
| | PSMB6 | Uncharacterized protein. (334 aa) |
| | WDR5 | WD repeat domain 5. (389 aa) |
| | ASB18 | Ankyrin repeat and SOCS box containing 18. (437 aa) |
| | KLHL5 | Kelch like family member 5. (754 aa) |
| | FBXO9 | F-box domain-containing protein. (448 aa) |
| | ELOB | Elongin B. (140 aa) |
| | CAND1 | Cullin associated and neddylation dissociated 1. (1229 aa) |
| | PSME3 | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (265 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa) |
| | ASB1 | Ankyrin repeat and SOCS box containing 1. (463 aa) |
| | CUL2 | Cullin 2; Belongs to the cullin family. (746 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (469 aa) |
| | FBXO7 | F-box protein 7. (606 aa) |
| | KLHL42 | Kelch like family member 42. (505 aa) |
| | COPS7A | COP9 signalosome subunit 7A. (296 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | CUL7 | Cullin-7 isoform X6; Belongs to the cullin family. (1691 aa) |
| | BTBD1 | BTB/POZ domain-containing protein 1 isoform 1. (484 aa) |
| | PSME1 | Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). (284 aa) |
| | DCAF11 | DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family. (597 aa) |
| | PSMB11 | Proteasome subunit beta. (291 aa) |
| | KLHL25 | Kelch like family member 25. (405 aa) |
| | PSMC1 | 26S proteasome regulatory subunit 4 isoform a; Belongs to the AAA ATPase family. (440 aa) |
| | FBXL8 | F-box domain-containing protein. (373 aa) |
| | HIF3A | Hypoxia inducible factor 3 subunit alpha. (671 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | LRRC41 | Leucine rich repeat containing 41. (812 aa) |
| | FBXL4 | F-box and leucine-rich repeat protein 4. (621 aa) |
| | COPS2 | COP9 signalosome subunit 2. (450 aa) |
| | FBXO15 | F-box only protein 15 isoform 2. (514 aa) |
| | LRR1 | Leucine-rich repeat protein 1 isoform 1. (424 aa) |
| | KLHL9 | Kelch like family member 9. (617 aa) |
| | DCAF10 | DDB1-and CUL4-associated factor 10 isoform X1. (562 aa) |
| | PSMB7 | Proteasome subunit beta type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...] (277 aa) |
| | ASB6 | Ankyrin repeat and SOCS box containing 6. (425 aa) |
| | FBXW5 | F-box and WD repeat domain containing 5. (567 aa) |
| | DCAF13 | DDB1 and CUL4 associated factor 13. (444 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (380 aa) |
| | PSMA5 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (232 aa) |
| | NEURL2 | Neuralized E3 ubiquitin protein ligase 2. (285 aa) |
| | DCUN1D3 | DCN1-like protein. (304 aa) |
| | FBXL16 | F-box and leucine rich repeat protein 16. (537 aa) |
| | COMMD1 | Copper metabolism domain containing 1. (189 aa) |
| | ASB3 | Ankyrin repeat and SOCS box protein 3 isoform X1. (525 aa) |
| | FBXL5 | F-box and leucine rich repeat protein 5. (691 aa) |
| | KLHL2 | Kelch like family member 2. (593 aa) |
| | COPS4 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] (406 aa) |
| | WSB2 | WD repeat and SOCS box containing 2. (448 aa) |
| | FBXO21 | F-box protein 21. (613 aa) |
| | KLHL22 | Kelch like family member 22. (634 aa) |
| | FBXW4 | F-box and WD repeat domain containing 4. (630 aa) |
| | COMMD3 | COMM domain containing 3. (195 aa) |
| | CISH | Cytokine-inducible SH2-containing protein isoform 2. (254 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (450 aa) |
| | KBTBD8 | Kelch repeat and BTB domain-containing protein 8 isoform X1. (601 aa) |
| | VHL | Von Hippel-Lindau disease tumor suppressor isoform 1. (205 aa) |
| | COMMD2 | COMM domain containing 2. (199 aa) |
| | FBXO40 | F-box only protein 40. (706 aa) |
| | ASB11 | Ankyrin repeat and SOCS box containing 11. (323 aa) |
| | CCDC22 | Coiled-coil domain containing 22. (716 aa) |
| | CUL4B | Cullin 4B; Belongs to the cullin family. (1056 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1139 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (458 aa) |
| | KXD1 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (305 aa) |
| | COMMD10 | COMM domain containing 10. (205 aa) |
| | FBXL21P | F-box domain-containing protein. (420 aa) |
| | RBBP5 | RB binding protein 5, histone lysine methyltransferase complex subunit. (517 aa) |
| | ASB4 | Ankyrin repeat and SOCS box protein 4 isoform a. (426 aa) |
| | PSMC2 | AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa) |
| | COP1 | E3 ubiquitin-protein ligase RFWD2 isoform a. (730 aa) |
| | DTL | Denticleless E3 ubiquitin protein ligase homolog. (729 aa) |
| | DCAF17 | DDB1 and CUL4 associated factor 17. (490 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | COPS8 | COP9 signalosome subunit 8. (212 aa) |
| | NUB1 | Negative regulator of ubiquitin like proteins 1. (616 aa) |
| | SKP2 | S-phase kinase-associated protein 2 isoform 1. (436 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (534 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (421 aa) |
| | SENP8 | SUMO peptidase family member, NEDD8 specific. (212 aa) |
| | ASB10 | Ankyrin repeat and SOCS box protein 10 isoform 1. (465 aa) |
| | FEM1B | Protein fem-1 homolog B. (627 aa) |
| | ASB5 | Ankyrin repeat and SOCS box containing 5. (347 aa) |
| | CUL5 | Cullin-5; Belongs to the cullin family. (780 aa) |
| | PSMF1 | Uncharacterized protein. (351 aa) |
| | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (305 aa) |
| | FBXO10 | F-box protein 10. (952 aa) |
| | KCTD6 | Potassium channel tetramerization domain containing 6. (261 aa) |
| | FBXL19 | F-box and leucine rich repeat protein 19. (694 aa) |
| | UBXN7 | UBX domain-containing protein. (519 aa) |
| | RNF7 | Ring finger protein 7. (113 aa) |
| | ASB8 | Ankyrin repeat and SOCS box protein 8 isoform a. (288 aa) |
| | FBXL7 | F-box and leucine rich repeat protein 7. (491 aa) |
| | ASB9 | Ankyrin repeat and SOCS box protein 9 isoform 2. (263 aa) |
| | DDA1 | DET1 and DDB1 associated 1. (102 aa) |
| | ASB15 | Ankyrin repeat and SOCS box containing 15. (613 aa) |
| | SPSB1 | SplA/ryanodine receptor domain and SOCS box containing 1. (273 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | FBXL3 | F-box and leucine rich repeat protein 3. (429 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (802 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | UBE2D2 | Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (146 aa) |
| | COPS7B | COP9 signalosome subunit 7B. (280 aa) |
| | A0A286ZS34_PIG | Uncharacterized protein. (179 aa) |
| | FBXW2 | F-box domain-containing protein. (234 aa) |
| | ASB17 | Ankyrin repeat and SOCS box containing 17. (295 aa) |
| | WSB1 | WD repeat and SOCS box-containing protein 1 isoform 1. (421 aa) |
| | LMO7 | LIM domain 7. (1598 aa) |
| | KLHL11 | Kelch like family member 11. (744 aa) |
| | A0A286ZW56_PIG | Uncharacterized protein. (277 aa) |
| | FBXL12 | F-box and leucine rich repeat protein 12. (411 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 isoform 1. (456 aa) |
| | DCUN1D2 | DCN1-like protein. (259 aa) |
| | KBTBD7 | Kelch repeat and BTB domain containing 7. (641 aa) |
| | ASB2 | Ankyrin repeat and SOCS box containing 2. (607 aa) |
| | FEM1A | Protein fem-1 homolog A. (664 aa) |
| | FBXL14 | F-box and leucine rich repeat protein 14. (375 aa) |
| | UFD1 | Ubiquitin recognition factor in ER associated degradation 1. (338 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (773 aa) |
| | DCAF6 | DDB1-and CUL4-associated factor 6 isoform c. (942 aa) |
| | FBXL13 | F-box and leucine rich repeat protein 13. (737 aa) |
| | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 isoform 1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | GPS1 | G protein pathway suppressor 1. (664 aa) |
| | BTBD6 | BTB domain containing 6. (538 aa) |
| | FBXO41 | F-box protein 41. (874 aa) |
| | COMMD5 | COMM domain containing 5. (260 aa) |
| | COPS5 | COP9 signalosome subunit 5. (409 aa) |
| | FBXO2 | F-box protein 2. (322 aa) |
| | KLHL20 | Kelch like family member 20. (788 aa) |
| | COPS6 | COP9 signalosome complex subunit 6; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with [...] (358 aa) |
| | DDB2 | DNA damage-binding protein 2 isoform WT. (448 aa) |
| | DCAF8 | DDB1 and CUL4 associated factor 8. (639 aa) |
| | NEDD8 | NEDD8 ubiquitin like modifier. (71 aa) |
| | BIRC5 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] (142 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | SOCS6 | Suppressor of cytokine signaling 6 isoform X1. (535 aa) |
| | KLHL13 | Kelch like family member 13. (692 aa) |
| | KLHL41 | Kelch like family member 41. (601 aa) |
| | KBTBD13 | Kelch repeat and BTB domain containing 13. (455 aa) |
| | CCNF | Cyclin F; Belongs to the cyclin family. (788 aa) |
| | FEM1C | Protein fem-1 homolog C isoform X1. (617 aa) |
| | SPSB2 | Uncharacterized protein. (263 aa) |
| | PSME4 | Proteasome activator complex subunit 4. (1843 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa) |
