STRINGSTRING
PCSK5 PCSK5 ANGPTL3 ANGPTL3 LIPC LIPC PCSK6 PCSK6 ANGPTL4 ANGPTL4 LMF1 LMF1 GPIHBP1 GPIHBP1 ANGPTL8 ANGPTL8 FURIN FURIN LMF2 LMF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1886 aa)
ANGPTL3Fibrinogen C-terminal domain-containing protein. (461 aa)
LIPCLipase C, hepatic type. (501 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6 isoform PACE4-AI preproprotein; Belongs to the peptidase S8 family. (965 aa)
ANGPTL4Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] (412 aa)
LMF1Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (565 aa)
GPIHBP1Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (180 aa)
ANGPTL8Angiopoietin-like protein 8. (198 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (797 aa)
LMF2Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (777 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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