STRINGSTRING
ARHGAP21 ARHGAP21 RACGAP1 RACGAP1 ARHGAP9 ARHGAP9 ARHGEF25 ARHGEF25 DEF6 DEF6 IQGAP1 IQGAP1 ARHGAP35 ARHGAP35 TAGAP TAGAP PAK6 PAK6 DAAM1 DAAM1 ARHGAP39 ARHGAP39 IQGAP3 IQGAP3 VANGL1 VANGL1 ARHGAP29 ARHGAP29 FNBP1L FNBP1L DLC1 DLC1 ARHGAP10 ARHGAP10 ARHGAP24 ARHGAP24 DIAPH3 DIAPH3 KCTD3 KCTD3 PAK2 PAK2 TIAM1 TIAM1 FGD1 FGD1 DOCK11 DOCK11 ARHGAP4 ARHGAP4 CDC42EP2 CDC42EP2 SYDE1 SYDE1 MYO9B MYO9B GMIP GMIP ARHGAP42 ARHGAP42 DOCK10 DOCK10 WDR91 WDR91 TRIO TRIO ARHGAP27 ARHGAP27 JUP JUP GIT1 GIT1 PLEKHG3 PLEKHG3 FGD3 FGD3 PLEKHG2 PLEKHG2 CPNE8 CPNE8 ARHGAP45 ARHGAP45 ARHGAP5 ARHGAP5 ARAP1 ARAP1 ARHGAP31 ARHGAP31 ARFGAP2 ARFGAP2 GOLGA2 GOLGA2 ARHGAP20 ARHGAP20 PIK3R1 PIK3R1 ARHGEF15 ARHGEF15 ARHGEF5 ARHGEF5 GNA13 GNA13 DNMBP DNMBP STARD8 STARD8 ARHGAP26 ARHGAP26 WIPF1 WIPF1 PLEKHG1 PLEKHG1 ARHGEF6 ARHGEF6 SNAP23 SNAP23 SHKBP1 SHKBP1 BCR BCR ARHGAP30 ARHGAP30 ARHGEF16 ARHGEF16 CHN1 CHN1 ARHGDIA ARHGDIA LBR LBR ARHGEF26 ARHGEF26 NGEF NGEF ARHGEF12 ARHGEF12 DOCK9 DOCK9 WDR81 WDR81 STEAP3 STEAP3 FMNL1 FMNL1 FAM13B FAM13B ARHGAP1 ARHGAP1 ARHGEF19 ARHGEF19 ARHGDIB ARHGDIB CDC42EP5 CDC42EP5 MCF2L MCF2L MAP3K11 MAP3K11 STOM STOM CDC42SE2 CDC42SE2 DOCK6 DOCK6 SRGAP3 SRGAP3 FGD4 FGD4 SRGAP1 SRGAP1 CDC42EP4 CDC42EP4 ARHGAP17 ARHGAP17 ARHGAP22 ARHGAP22 ARAP2 ARAP2 CDC42EP1 CDC42EP1 BAIAP2 BAIAP2 ARHGDIG ARHGDIG SRGAP2 SRGAP2 ARHGAP32 ARHGAP32 ABR ABR PIK3R2 PIK3R2 WASL WASL DEPDC1B DEPDC1B ITSN1 ITSN1 FNBP1 FNBP1 VAV3 VAV3 PARD6A PARD6A ARHGEF11 ARHGEF11 ARHGAP33 ARHGAP33 FARP1 FARP1 PAK5 PAK5 OPHN1 OPHN1 VAMP3 VAMP3 VAV2 VAV2 ARHGAP44 ARHGAP44 YKT6 YKT6 CDC42EP3 CDC42EP3 LAMTOR1 LAMTOR1 FMNL2 FMNL2 IQGAP2 IQGAP2 TFRC TFRC CDC42 CDC42 PAK1 PAK1 DOCK7 DOCK7 ECT2 ECT2 ARHGEF9 ARHGEF9 MCF2 MCF2 ARFGAP3 ARFGAP3 RAB7A RAB7A ARHGEF7 ARHGEF7 FGD2 FGD2 PREX2 PREX2 SPATA13 SPATA13 CDC42BPB CDC42BPB PREX1 PREX1 RASGRF2 RASGRF2 SH3PXD2A SH3PXD2A DOCK8 DOCK8 CDC42BPA CDC42BPA PLD1 PLD1 KTN1 KTN1 ARAP3 ARAP3 GIT2 GIT2 RALBP1 RALBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARHGAP21Rho GTPase activating protein 21. (1852 aa)
RACGAP1Rac GTPase activating protein 1. (634 aa)
ARHGAP9Rho GTPase activating protein 9. (808 aa)
ARHGEF25Rho guanine nucleotide exchange factor 25 isoform X1. (590 aa)
DEF6Differentially expressed in FDCP 6 homolog. (631 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1709 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
TAGAPRho-GAP domain-containing protein. (838 aa)
PAK6Non-specific serine/threonine protein kinase. (709 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1086 aa)
ARHGAP39Rho GTPase activating protein 39. (1112 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1696 aa)
VANGL1Vang-like protein. (524 aa)
ARHGAP29Rho GTPase-activating protein 29 isoform a. (1260 aa)
FNBP1LFormin binding protein 1 like. (609 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
ARHGAP10Rho GTPase-activating protein 10. (762 aa)
ARHGAP24Rho GTPase activating protein 24. (749 aa)
DIAPH3Diaphanous related formin 3. (1138 aa)
KCTD3Potassium channel tetramerization domain containing 3. (774 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1611 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (960 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2056 aa)
ARHGAP4Rho GTPase activating protein 4. (979 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (214 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (735 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2194 aa)
GMIPGEM interacting protein. (1090 aa)
ARHGAP42Rho GTPase activating protein 42. (871 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2201 aa)
WDR91WD repeat-containing protein 91. (746 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3109 aa)
ARHGAP27Rho GTPase activating protein 27. (863 aa)
JUPJunction plakoglobin; Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E- cadherin/catenin adhes [...] (744 aa)
GIT1GIT ArfGAP 1. (761 aa)
PLEKHG3Pleckstrin homology and RhoGEF domain containing G3. (1359 aa)
FGD3FYVE, RhoGEF and PH domain-containing protein 3 isoform X1. (735 aa)
PLEKHG2Pleckstrin homology and RhoGEF domain containing G2. (1357 aa)
CPNE8Copine-8. (577 aa)
ARHGAP45Rho GTPase activating protein 45. (1156 aa)
ARHGAP5Rho GTPase-activating protein 5 isoform X1. (1503 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1458 aa)
ARHGAP31Rho GTPase-activating protein 31. (1453 aa)
ARFGAP2ADP ribosylation factor GTPase activating protein 2. (537 aa)
GOLGA2Uncharacterized protein. (1032 aa)
ARHGAP20Rho GTPase activating protein 20. (1189 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (766 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (844 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1574 aa)
GNA13G protein subunit alpha 13. (377 aa)
DNMBPDynamin binding protein. (1581 aa)
STARD8StAR related lipid transfer domain containing 8. (1113 aa)
ARHGAP26Rho GTPase activating protein 26. (734 aa)
WIPF1WH2 domain-containing protein. (515 aa)
PLEKHG1Pleckstrin homology and RhoGEF domain containing G1. (1372 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (773 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (222 aa)
SHKBP1SH3KBP1 binding protein 1. (729 aa)
BCRBCR activator of RhoGEF and GTPase. (1274 aa)
ARHGAP30Rho GTPase activating protein 30. (1071 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (766 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (270 aa)
LBRLamin-B receptor. (626 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (872 aa)
NGEFNeuronal guanine nucleotide exchange factor. (823 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2290 aa)
WDR81WD repeat-containing protein 81 isoform X1. (1945 aa)
STEAP3STEAP3 metalloreductase. (526 aa)
FMNL1Formin like 1. (1175 aa)
FAM13BFamily with sequence similarity 13 member B. (937 aa)
ARHGAP1Rho GTPase activating protein 1. (450 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19 isoform X1. (879 aa)
ARHGDIBUncharacterized protein. (200 aa)
CDC42EP5CDC42 effector protein 5. (153 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (1298 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (858 aa)
STOMStomatin. (267 aa)
CDC42SE2CDC42 small effector 2. (107 aa)
DOCK6Dedicator of cytokinesis 6; Belongs to the DOCK family. (2123 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1074 aa)
FGD4Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1415 aa)
SRGAP1SLIT-ROBO Rho GTPase-activating protein 1 isoform X1. (1085 aa)
CDC42EP4CDC42 effector protein 4. (357 aa)
ARHGAP17Rho GTPase activating protein 17. (930 aa)
ARHGAP22Rho GTPase-activating protein 22 isoform X1. (722 aa)
ARAP2ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2. (1735 aa)
CDC42EP1Cdc42 effector protein 1 isoform X1. (376 aa)
BAIAP2BAI1 associated protein 2. (575 aa)
ARHGDIGRho GDP dissociation inhibitor gamma. (267 aa)
SRGAP2Uncharacterized protein. (1087 aa)
ARHGAP32Rho GTPase activating protein 32. (2089 aa)
ABRABR activator of RhoGEF and GTPase. (964 aa)
PIK3R2Uncharacterized protein. (772 aa)
WASLWASP like actin nucleation promoting factor. (511 aa)
DEPDC1BDEP domain containing 1B. (725 aa)
ITSN1Intersectin 1. (1485 aa)
FNBP1Formin binding protein 1. (616 aa)
VAV3Vav guanine nucleotide exchange factor 3. (874 aa)
PARD6APar-6 family cell polarity regulator alpha. (354 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1577 aa)
ARHGAP33Rho GTPase activating protein 33. (1310 aa)
FARP1FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1052 aa)
PAK5Non-specific serine/threonine protein kinase. (744 aa)
OPHN1Oligophrenin 1. (808 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (217 aa)
VAV2Vav guanine nucleotide exchange factor 2. (879 aa)
ARHGAP44Rho GTPase activating protein 44. (812 aa)
YKT6Uncharacterized protein; Belongs to the synaptobrevin family. (221 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (204 aa)
FMNL2Formin like 2. (1092 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1542 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (794 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
PAK1Non-specific serine/threonine protein kinase. (546 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2312 aa)
ECT2Epithelial cell transforming 2. (1028 aa)
ARHGEF9Uncharacterized protein. (1109 aa)
MCF2MCF.2 cell line derived transforming sequence. (1172 aa)
ARFGAP3ADP ribosylation factor GTPase activating protein 3. (613 aa)
RAB7ARAB7A, member RAS oncogene family. (252 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (656 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1614 aa)
SPATA13Uncharacterized protein. (1159 aa)
CDC42BPBSerine/threonine-protein kinase MRCK beta isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1712 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1615 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1270 aa)
SH3PXD2ASH3 and PX domain-containing protein 2A. (1133 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (1998 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1847 aa)
PLD1Phospholipase. (1074 aa)
KTN1Kinectin 1. (1358 aa)
ARAP3Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5. (1545 aa)
GIT2GIT ArfGAP 2. (853 aa)
RALBP1RalA binding protein 1. (639 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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