STRINGSTRING
TIAM1 TIAM1 RACGAP1 RACGAP1 ARHGAP9 ARHGAP9 ARHGEF25 ARHGEF25 AMIGO2 AMIGO2 DEF6 DEF6 IQGAP1 IQGAP1 SLC1A5 SLC1A5 ARHGAP35 ARHGAP35 EPHA2 EPHA2 TAGAP TAGAP TIAM2 TIAM2 NOX3 NOX3 PAK6 PAK6 SOS2 SOS2 ARHGAP39 ARHGAP39 IQGAP3 IQGAP3 VANGL1 VANGL1 ARHGAP29 ARHGAP29 SYDE2 SYDE2 DLC1 DLC1 JAG1 JAG1 BAIAP2L1 BAIAP2L1 NCF1 NCF1 NOXO1 NOXO1 SOS1 SOS1 ARHGAP10 ARHGAP10 ARHGAP24 ARHGAP24 WASF3 WASF3 DIAPH3 DIAPH3 DOCK5 DOCK5 TAOK3 TAOK3 ABI1 ABI1 NISCH NISCH BRK1 BRK1 FGD5 FGD5 PAK2 PAK2 DOCK11 DOCK11 ARHGAP4 ARHGAP4 MYO9B MYO9B GMIP GMIP ARHGAP42 ARHGAP42 DOCK10 DOCK10 TRIO TRIO DOCK2 DOCK2 ARHGAP27 ARHGAP27 GIT1 GIT1 PLD2 PLD2 PLEKHG3 PLEKHG3 SH3BP1 SH3BP1 PLEKHG2 PLEKHG2 ARHGAP45 ARHGAP45 ARHGAP5 ARHGAP5 ARAP1 ARAP1 FAM13A FAM13A WASF2 WASF2 ARHGAP31 ARHGAP31 ARHGAP20 ARHGAP20 PIK3R1 PIK3R1 ARHGEF15 ARHGEF15 ARHGEF5 ARHGEF5 ARHGAP21 ARHGAP21 IQGAP2 IQGAP2 NHS NHS TFRC TFRC CDC42 CDC42 NOX1 NOX1 PAK1 PAK1 DOCK7 DOCK7 ECT2 ECT2 VRK2 VRK2 MCF2 MCF2 PKN2 PKN2 RAB7A RAB7A ARHGEF7 ARHGEF7 VAV1 VAV1 PREX2 PREX2 SPATA13 SPATA13 PREX1 PREX1 RASGRF2 RASGRF2 NCF2 NCF2 DOCK8 DOCK8 ARHGAP25 ARHGAP25 CDC42BPA CDC42BPA PLD1 PLD1 KTN1 KTN1 ARAP3 ARAP3 ARHGEF18 ARHGEF18 ABI2 ABI2 DOCK1 DOCK1 GIT2 GIT2 RALBP1 RALBP1 KIAA0355 KIAA0355 ARHGAP23 ARHGAP23 GNA13 GNA13 ALS2 ALS2 ARHGAP26 ARHGAP26 WIPF1 WIPF1 PLEKHG1 PLEKHG1 ARHGEF6 ARHGEF6 SNAP23 SNAP23 BCR BCR NCKAP1 NCKAP1 DOCK3 DOCK3 ARHGAP30 ARHGAP30 CHN1 CHN1 WASF1 WASF1 ARHGDIA ARHGDIA MPP7 MPP7 LBR LBR NGEF NGEF ARHGAP12 ARHGAP12 ABL2 ABL2 CYFIP2 CYFIP2 DOCK9 DOCK9 FMNL1 FMNL1 FAM13B FAM13B PKN1 PKN1 NOXA1 NOXA1 ARHGAP1 ARHGAP1 ARHGEF19 ARHGEF19 ARHGDIB ARHGDIB MCF2L MCF2L DOCK6 DOCK6 SRGAP3 SRGAP3 SRGAP1 SRGAP1 CDC42EP4 CDC42EP4 PIK3CA PIK3CA LOC100511937 LOC100511937 RBM39 RBM39 ARHGAP17 ARHGAP17 ARHGAP22 ARHGAP22 ARAP2 ARAP2 CDC42EP1 CDC42EP1 DOCK4 DOCK4 BAIAP2 BAIAP2 ARHGAP15 ARHGAP15 CHN2 CHN2 PLEKHG6 PLEKHG6 FARP2 FARP2 SRGAP2 SRGAP2 ARHGAP32 ARHGAP32 ABR ABR PIK3R2 PIK3R2 SWAP70 SWAP70 WASL WASL ARHGEF39 ARHGEF39 RAC1 RAC1 DEPDC1B DEPDC1B FERMT2 FERMT2 NCKAP1L NCKAP1L MCAM MCAM VAV3 VAV3 PARD6A PARD6A ARHGEF11 ARHGEF11 ARHGAP33 ARHGAP33 FARP1 FARP1 PAK5 PAK5 OPHN1 OPHN1 EMD EMD ESYT1 ESYT1 VAMP3 VAMP3 VAV2 VAV2 ARHGAP44 ARHGAP44 YKT6 YKT6 CIT CIT LAMTOR1 LAMTOR1 NCF4 NCF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TIAM1T cell lymphoma invasion and metastasis 1. (1611 aa)
RACGAP1Rac GTPase activating protein 1. (634 aa)
ARHGAP9Rho GTPase activating protein 9. (808 aa)
ARHGEF25Rho guanine nucleotide exchange factor 25 isoform X1. (590 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
DEF6Differentially expressed in FDCP 6 homolog. (631 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1709 aa)
SLC1A5Amino acid transporter. (541 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
EPHA2Ephrin type-A receptor 2 isoform 1. (975 aa)
TAGAPRho-GAP domain-containing protein. (838 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1704 aa)
NOX3NADPH oxidase 3. (568 aa)
PAK6Non-specific serine/threonine protein kinase. (709 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
ARHGAP39Rho GTPase activating protein 39. (1112 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1696 aa)
VANGL1Vang-like protein. (524 aa)
ARHGAP29Rho GTPase-activating protein 29 isoform a. (1260 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1190 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1211 aa)
BAIAP2L1BAI1 associated protein 2 like 1. (509 aa)
NCF1Uncharacterized protein. (378 aa)
NOXO1NADPH oxidase organizer 1. (400 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1369 aa)
ARHGAP10Rho GTPase-activating protein 10. (762 aa)
ARHGAP24Rho GTPase activating protein 24. (749 aa)
WASF3Wiskott-Aldrich syndrome protein family member 3 isoform X1. (498 aa)
DIAPH3Diaphanous related formin 3. (1138 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1867 aa)
TAOK3TAO kinase 3. (898 aa)
ABI1Abl interactor 1 isoform b. (481 aa)
NISCHNischarin. (1520 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (103 aa)
FGD5FYVE, RhoGEF and PH domain-containing protein 5 isoform 1. (1499 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2056 aa)
ARHGAP4Rho GTPase activating protein 4. (979 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2194 aa)
GMIPGEM interacting protein. (1090 aa)
ARHGAP42Rho GTPase activating protein 42. (871 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2201 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3109 aa)
DOCK2Dedicator of cytokinesis protein 2; Belongs to the DOCK family. (1827 aa)
ARHGAP27Rho GTPase activating protein 27. (863 aa)
GIT1GIT ArfGAP 1. (761 aa)
PLD2Phospholipase. (933 aa)
PLEKHG3Pleckstrin homology and RhoGEF domain containing G3. (1359 aa)
SH3BP1Uncharacterized protein. (643 aa)
PLEKHG2Pleckstrin homology and RhoGEF domain containing G2. (1357 aa)
ARHGAP45Rho GTPase activating protein 45. (1156 aa)
ARHGAP5Rho GTPase-activating protein 5 isoform X1. (1503 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1458 aa)
FAM13AFamily with sequence similarity 13 member A. (1020 aa)
WASF2Wiskott-Aldrich syndrome protein family member 2 isoform 2. (498 aa)
ARHGAP31Rho GTPase-activating protein 31. (1453 aa)
ARHGAP20Rho GTPase activating protein 20. (1189 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (766 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (844 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1574 aa)
ARHGAP21Rho GTPase activating protein 21. (1852 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1542 aa)
NHSNHS actin remodeling regulator. (1621 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (794 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
NOX1NADPH oxidase 1 isoform 1. (564 aa)
PAK1Non-specific serine/threonine protein kinase. (546 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2312 aa)
ECT2Epithelial cell transforming 2. (1028 aa)
VRK2Serine/threonine-protein kinase VRK2. (507 aa)
MCF2MCF.2 cell line derived transforming sequence. (1172 aa)
PKN2Serine/threonine-protein kinase N2 isoform 1. (983 aa)
RAB7ARAB7A, member RAS oncogene family. (252 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1614 aa)
SPATA13Uncharacterized protein. (1159 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1615 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1270 aa)
NCF2Neutrophil cytosolic factor 2. (643 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (1998 aa)
ARHGAP25Rho GTPase activating protein 25. (748 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1847 aa)
PLD1Phospholipase. (1074 aa)
KTN1Kinectin 1. (1358 aa)
ARAP3Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5. (1545 aa)
ARHGEF18Rho guanine nucleotide exchange factor 18 isoform X3. (1346 aa)
ABI2Abl interactor 2. (542 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1828 aa)
GIT2GIT ArfGAP 2. (853 aa)
RALBP1RalA binding protein 1. (639 aa)
KIAA0355KIAA0355. (1074 aa)
ARHGAP23Rho GTPase activating protein 23. (1145 aa)
GNA13G protein subunit alpha 13. (377 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1662 aa)
ARHGAP26Rho GTPase activating protein 26. (734 aa)
WIPF1WH2 domain-containing protein. (515 aa)
PLEKHG1Pleckstrin homology and RhoGEF domain containing G1. (1372 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (773 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (222 aa)
BCRBCR activator of RhoGEF and GTPase. (1274 aa)
NCKAP1NCK associated protein 1. (1134 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2071 aa)
ARHGAP30Rho GTPase activating protein 30. (1071 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
WASF1WH2 domain-containing protein. (559 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (270 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (601 aa)
LBRLamin-B receptor. (626 aa)
NGEFNeuronal guanine nucleotide exchange factor. (823 aa)
ARHGAP12Rho GTPase activating protein 12. (880 aa)
ABL2Tyrosine-protein kinase. (1096 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2290 aa)
FMNL1Formin like 1. (1175 aa)
FAM13BFamily with sequence similarity 13 member B. (937 aa)
PKN1Protein kinase N1. (956 aa)
NOXA1NADPH oxidase activator 1. (474 aa)
ARHGAP1Rho GTPase activating protein 1. (450 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19 isoform X1. (879 aa)
ARHGDIBUncharacterized protein. (200 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (1298 aa)
DOCK6Dedicator of cytokinesis 6; Belongs to the DOCK family. (2123 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1074 aa)
SRGAP1SLIT-ROBO Rho GTPase-activating protein 1 isoform X1. (1085 aa)
CDC42EP4CDC42 effector protein 4. (357 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC100511937Uncharacterized protein. (532 aa)
RBM39RNA-binding protein 39 isoform a. (530 aa)
ARHGAP17Rho GTPase activating protein 17. (930 aa)
ARHGAP22Rho GTPase-activating protein 22 isoform X1. (722 aa)
ARAP2ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2. (1735 aa)
CDC42EP1Cdc42 effector protein 1 isoform X1. (376 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1977 aa)
BAIAP2BAI1 associated protein 2. (575 aa)
ARHGAP15Rho GTPase activating protein 15. (497 aa)
CHN2Chimaerin; GTPase-activating protein for p21-rac. (468 aa)
PLEKHG6Pleckstrin homology domain-containing family G member 6 isoform X1. (791 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1163 aa)
SRGAP2Uncharacterized protein. (1087 aa)
ARHGAP32Rho GTPase activating protein 32. (2089 aa)
ABRABR activator of RhoGEF and GTPase. (964 aa)
PIK3R2Uncharacterized protein. (772 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
WASLWASP like actin nucleation promoting factor. (511 aa)
ARHGEF39Rho guanine nucleotide exchange factor 39. (370 aa)
RAC1Rac family small GTPase 1. (186 aa)
DEPDC1BDEP domain containing 1B. (725 aa)
FERMT2Fermitin family member 2. (776 aa)
NCKAP1LNCK associated protein 1 like. (1128 aa)
MCAMMelanoma cell adhesion molecule. (667 aa)
VAV3Vav guanine nucleotide exchange factor 3. (874 aa)
PARD6APar-6 family cell polarity regulator alpha. (354 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1577 aa)
ARHGAP33Rho GTPase activating protein 33. (1310 aa)
FARP1FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1052 aa)
PAK5Non-specific serine/threonine protein kinase. (744 aa)
OPHN1Oligophrenin 1. (808 aa)
EMDLEM domain-containing protein. (400 aa)
ESYT1Extended synaptotagmin 1. (1109 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (217 aa)
VAV2Vav guanine nucleotide exchange factor 2. (879 aa)
ARHGAP44Rho GTPase activating protein 44. (812 aa)
YKT6Uncharacterized protein; Belongs to the synaptobrevin family. (221 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2104 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (204 aa)
NCF4Neutrophil cytosolic factor 4. (381 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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