STRINGSTRING
MPP7 MPP7 LBR LBR DSG2 DSG2 ARHGAP1 ARHGAP1 CDC42EP4 CDC42EP4 PIK3CA PIK3CA LOC100511937 LOC100511937 RBM39 RBM39 ARHGAP17 ARHGAP17 CDC42EP1 CDC42EP1 DOCK4 DOCK4 ARHGAP32 ARHGAP32 ABR ABR VAPB VAPB PIK3R2 PIK3R2 SWAP70 SWAP70 DEPDC1B DEPDC1B NCKAP1L NCKAP1L MCAM MCAM VAV3 VAV3 OPHN1 OPHN1 RAC2 RAC2 EMD EMD ESYT1 ESYT1 VAMP3 VAMP3 VAV2 VAV2 LAMTOR1 LAMTOR1 NCF4 NCF4 ABI2 ABI2 RACGAP1 RACGAP1 DEF6 DEF6 IQGAP1 IQGAP1 ARHGAP35 ARHGAP35 EPHA2 EPHA2 LMAN1 LMAN1 ARHGAP39 ARHGAP39 MTX1 MTX1 VANGL1 VANGL1 BAIAP2L1 BAIAP2L1 NCF1 NCF1 DIAPH3 DIAPH3 SLITRK5 SLITRK5 TAOK3 TAOK3 ABI1 ABI1 BRK1 BRK1 PAK2 PAK2 TIAM1 TIAM1 SYDE1 SYDE1 ARHGAP42 ARHGAP42 DOCK10 DOCK10 TRIO TRIO DOCK2 DOCK2 GIT1 GIT1 PLD2 PLD2 WASF2 WASF2 PIK3R1 PIK3R1 ARHGAP21 ARHGAP21 ANKLE2 ANKLE2 NHS NHS TFRC TFRC CDC42 CDC42 PAK1 PAK1 VRK2 VRK2 MCF2 MCF2 RAB7A RAB7A VAV1 VAV1 PREX1 PREX1 NCF2 NCF2 DOCK1 DOCK1 GIT2 GIT2 KIAA0355 KIAA0355 SAMM50 SAMM50 ARHGAP26 ARHGAP26 BCR BCR NCKAP1 NCKAP1 DOCK3 DOCK3 ARMCX3 ARMCX3 ARHGDIA ARHGDIA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (601 aa)
LBRLamin-B receptor. (626 aa)
DSG2Desmoglein 2. (1127 aa)
ARHGAP1Rho GTPase activating protein 1. (450 aa)
CDC42EP4CDC42 effector protein 4. (357 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC100511937Uncharacterized protein. (532 aa)
RBM39RNA-binding protein 39 isoform a. (530 aa)
ARHGAP17Rho GTPase activating protein 17. (930 aa)
CDC42EP1Cdc42 effector protein 1 isoform X1. (376 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1977 aa)
ARHGAP32Rho GTPase activating protein 32. (2089 aa)
ABRABR activator of RhoGEF and GTPase. (964 aa)
VAPBVesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. (309 aa)
PIK3R2Uncharacterized protein. (772 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
DEPDC1BDEP domain containing 1B. (725 aa)
NCKAP1LNCK associated protein 1 like. (1128 aa)
MCAMMelanoma cell adhesion molecule. (667 aa)
VAV3Vav guanine nucleotide exchange factor 3. (874 aa)
OPHN1Oligophrenin 1. (808 aa)
RAC2Rac family small GTPase 2. (217 aa)
EMDLEM domain-containing protein. (400 aa)
ESYT1Extended synaptotagmin 1. (1109 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (217 aa)
VAV2Vav guanine nucleotide exchange factor 2. (879 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (204 aa)
NCF4Neutrophil cytosolic factor 4. (381 aa)
ABI2Abl interactor 2. (542 aa)
RACGAP1Rac GTPase activating protein 1. (634 aa)
DEF6Differentially expressed in FDCP 6 homolog. (631 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1709 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
EPHA2Ephrin type-A receptor 2 isoform 1. (975 aa)
LMAN1Lectin, mannose binding 1. (518 aa)
ARHGAP39Rho GTPase activating protein 39. (1112 aa)
MTX1Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. (463 aa)
VANGL1Vang-like protein. (524 aa)
BAIAP2L1BAI1 associated protein 2 like 1. (509 aa)
NCF1Uncharacterized protein. (378 aa)
DIAPH3Diaphanous related formin 3. (1138 aa)
SLITRK5SLIT and NTRK-like protein 5 isoform X1. (963 aa)
TAOK3TAO kinase 3. (898 aa)
ABI1Abl interactor 1 isoform b. (481 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (103 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1611 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (735 aa)
ARHGAP42Rho GTPase activating protein 42. (871 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2201 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3109 aa)
DOCK2Dedicator of cytokinesis protein 2; Belongs to the DOCK family. (1827 aa)
GIT1GIT ArfGAP 1. (761 aa)
PLD2Phospholipase. (933 aa)
WASF2Wiskott-Aldrich syndrome protein family member 2 isoform 2. (498 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (766 aa)
ARHGAP21Rho GTPase activating protein 21. (1852 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (966 aa)
NHSNHS actin remodeling regulator. (1621 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (794 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
PAK1Non-specific serine/threonine protein kinase. (546 aa)
VRK2Serine/threonine-protein kinase VRK2. (507 aa)
MCF2MCF.2 cell line derived transforming sequence. (1172 aa)
RAB7ARAB7A, member RAS oncogene family. (252 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1615 aa)
NCF2Neutrophil cytosolic factor 2. (643 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1828 aa)
GIT2GIT ArfGAP 2. (853 aa)
KIAA0355KIAA0355. (1074 aa)
SAMM50SAMM50 sorting and assembly machinery component. (469 aa)
ARHGAP26Rho GTPase activating protein 26. (734 aa)
BCRBCR activator of RhoGEF and GTPase. (1274 aa)
NCKAP1NCK associated protein 1. (1134 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2071 aa)
ARMCX3Armadillo repeat-containing X-linked protein 3. (379 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (270 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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