STRINGSTRING
RHOG RHOG DOCK4 DOCK4 ARHGDIG ARHGDIG ARHGAP32 ARHGAP32 VAPB VAPB DEPDC1B DEPDC1B ITSN1 ITSN1 MCAM MCAM VAV3 VAV3 OPHN1 OPHN1 EMD EMD ESYT1 ESYT1 VAMP3 VAMP3 VAV2 VAV2 YKT6 YKT6 LAMTOR1 LAMTOR1 NDUFA5 NDUFA5 ARHGAP35 ARHGAP35 EPHA2 EPHA2 LMAN1 LMAN1 ARHGAP39 ARHGAP39 VANGL1 VANGL1 LETM1 LETM1 DIAPH3 DIAPH3 DOCK5 DOCK5 PAK2 PAK2 HSPE1 HSPE1 TRIO TRIO DOCK2 DOCK2 PLEKHG3 PLEKHG3 ARHGAP5 ARHGAP5 PIK3R1 PIK3R1 ARHGEF5 ARHGEF5 ARHGAP21 ARHGAP21 ELMO2 ELMO2 IQGAP2 IQGAP2 ANKLE2 ANKLE2 TFRC TFRC CDC42 CDC42 VRK2 VRK2 MCF2 MCF2 ARFGAP3 ARFGAP3 NDUFS3 NDUFS3 RAB7A RAB7A VAV1 VAV1 PREX1 PREX1 PLD1 PLD1 KTN1 KTN1 DOCK1 DOCK1 KIAA0355 KIAA0355 DOCK3 DOCK3 ARHGEF16 ARHGEF16 ARHGDIA ARHGDIA MPP7 MPP7 LBR LBR ARHGEF26 ARHGEF26 DSG2 DSG2 ARHGAP1 ARHGAP1 ARHGDIB ARHGDIB MCF2L MCF2L MAP3K11 MAP3K11 RBM39 RBM39 SHMT2 SHMT2 CDC42EP1 CDC42EP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOGUncharacterized protein. (394 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1977 aa)
ARHGDIGRho GDP dissociation inhibitor gamma. (267 aa)
ARHGAP32Rho GTPase activating protein 32. (2089 aa)
VAPBVesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. (309 aa)
DEPDC1BDEP domain containing 1B. (725 aa)
ITSN1Intersectin 1. (1485 aa)
MCAMMelanoma cell adhesion molecule. (667 aa)
VAV3Vav guanine nucleotide exchange factor 3. (874 aa)
OPHN1Oligophrenin 1. (808 aa)
EMDLEM domain-containing protein. (400 aa)
ESYT1Extended synaptotagmin 1. (1109 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (217 aa)
VAV2Vav guanine nucleotide exchange factor 2. (879 aa)
YKT6Uncharacterized protein; Belongs to the synaptobrevin family. (221 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (204 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (117 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
EPHA2Ephrin type-A receptor 2 isoform 1. (975 aa)
LMAN1Lectin, mannose binding 1. (518 aa)
ARHGAP39Rho GTPase activating protein 39. (1112 aa)
VANGL1Vang-like protein. (524 aa)
LETM1Leucine zipper and EF-hand containing transmembrane protein 1. (791 aa)
DIAPH3Diaphanous related formin 3. (1138 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1867 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
HSPE1Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3109 aa)
DOCK2Dedicator of cytokinesis protein 2; Belongs to the DOCK family. (1827 aa)
PLEKHG3Pleckstrin homology and RhoGEF domain containing G3. (1359 aa)
ARHGAP5Rho GTPase-activating protein 5 isoform X1. (1503 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (766 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1574 aa)
ARHGAP21Rho GTPase activating protein 21. (1852 aa)
ELMO2Engulfment and cell motility 2. (732 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1542 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (966 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (794 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
VRK2Serine/threonine-protein kinase VRK2. (507 aa)
MCF2MCF.2 cell line derived transforming sequence. (1172 aa)
ARFGAP3ADP ribosylation factor GTPase activating protein 3. (613 aa)
NDUFS3NADH dehydrogenase ubiquinone iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (264 aa)
RAB7ARAB7A, member RAS oncogene family. (252 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1615 aa)
PLD1Phospholipase. (1074 aa)
KTN1Kinectin 1. (1358 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1828 aa)
KIAA0355KIAA0355. (1074 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2071 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (766 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (270 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (601 aa)
LBRLamin-B receptor. (626 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (872 aa)
DSG2Desmoglein 2. (1127 aa)
ARHGAP1Rho GTPase activating protein 1. (450 aa)
ARHGDIBUncharacterized protein. (200 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (1298 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (858 aa)
RBM39RNA-binding protein 39 isoform a. (530 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (503 aa)
CDC42EP1Cdc42 effector protein 1 isoform X1. (376 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (26%) [HD]