STRINGSTRING
NOX3 NOX3 LMAN1 LMAN1 RAPGEF1 RAPGEF1 ARHGAP39 ARHGAP39 VANGL1 VANGL1 JAG1 JAG1 BAIAP2L1 BAIAP2L1 NCF1 NCF1 NOXO1 NOXO1 DIAPH3 DIAPH3 SLITRK5 SLITRK5 TAOK3 TAOK3 ABI1 ABI1 BRK1 BRK1 PAK2 PAK2 TIAM1 TIAM1 ARHGAP6 ARHGAP6 SYDE1 SYDE1 ARHGAP42 ARHGAP42 DOCK10 DOCK10 TRIO TRIO GIT1 GIT1 ARHGAP5 ARHGAP5 WASF2 WASF2 PIK3R1 PIK3R1 ARHGAP21 ARHGAP21 NHS NHS TFRC TFRC CDC42 CDC42 NOX1 NOX1 PAK1 PAK1 VRK2 VRK2 MCF2 MCF2 RAB7A RAB7A PREX1 PREX1 NCF2 NCF2 ARAP3 ARAP3 ABI2 ABI2 GIT2 GIT2 KIAA0355 KIAA0355 ARHGAP26 ARHGAP26 SNAP23 SNAP23 BCR BCR NCKAP1 NCKAP1 WASF1 WASF1 MPP7 MPP7 LBR LBR RAC3 RAC3 DSG2 DSG2 ABL2 ABL2 NOXA1 NOXA1 ARHGAP1 ARHGAP1 ARHGDIB ARHGDIB RBM39 RBM39 ARHGAP17 ARHGAP17 SLITRK3 SLITRK3 ARAP2 ARAP2 CDC42EP1 CDC42EP1 BAIAP2 BAIAP2 ARHGAP15 ARHGAP15 SRGAP2 SRGAP2 ARHGAP32 ARHGAP32 ABR ABR PIK3R2 PIK3R2 SWAP70 SWAP70 DEPDC1B DEPDC1B FERMT2 FERMT2 NCKAP1L NCKAP1L MCAM MCAM OCRL OCRL OPHN1 OPHN1 EMD EMD ESYT1 ESYT1 VAMP3 VAMP3 VAV2 VAV2 YKT6 YKT6 LAMTOR1 LAMTOR1 NCF4 NCF4 EPHA2 EPHA2 ARHGAP35 ARHGAP35 SLC1A5 SLC1A5 AMIGO2 AMIGO2 RACGAP1 RACGAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOX3NADPH oxidase 3. (568 aa)
LMAN1Lectin, mannose binding 1. (518 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1093 aa)
ARHGAP39Rho GTPase activating protein 39. (1112 aa)
VANGL1Vang-like protein. (524 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1211 aa)
BAIAP2L1BAI1 associated protein 2 like 1. (509 aa)
NCF1Uncharacterized protein. (378 aa)
NOXO1NADPH oxidase organizer 1. (400 aa)
DIAPH3Diaphanous related formin 3. (1138 aa)
SLITRK5SLIT and NTRK-like protein 5 isoform X1. (963 aa)
TAOK3TAO kinase 3. (898 aa)
ABI1Abl interactor 1 isoform b. (481 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (103 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1611 aa)
ARHGAP6Rho GTPase activating protein 6. (705 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (735 aa)
ARHGAP42Rho GTPase activating protein 42. (871 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2201 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3109 aa)
GIT1GIT ArfGAP 1. (761 aa)
ARHGAP5Rho GTPase-activating protein 5 isoform X1. (1503 aa)
WASF2Wiskott-Aldrich syndrome protein family member 2 isoform 2. (498 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (766 aa)
ARHGAP21Rho GTPase activating protein 21. (1852 aa)
NHSNHS actin remodeling regulator. (1621 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (794 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
NOX1NADPH oxidase 1 isoform 1. (564 aa)
PAK1Non-specific serine/threonine protein kinase. (546 aa)
VRK2Serine/threonine-protein kinase VRK2. (507 aa)
MCF2MCF.2 cell line derived transforming sequence. (1172 aa)
RAB7ARAB7A, member RAS oncogene family. (252 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1615 aa)
NCF2Neutrophil cytosolic factor 2. (643 aa)
ARAP3Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5. (1545 aa)
ABI2Abl interactor 2. (542 aa)
GIT2GIT ArfGAP 2. (853 aa)
KIAA0355KIAA0355. (1074 aa)
ARHGAP26Rho GTPase activating protein 26. (734 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (222 aa)
BCRBCR activator of RhoGEF and GTPase. (1274 aa)
NCKAP1NCK associated protein 1. (1134 aa)
WASF1WH2 domain-containing protein. (559 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (601 aa)
LBRLamin-B receptor. (626 aa)
RAC3Rac family small GTPase 3. (192 aa)
DSG2Desmoglein 2. (1127 aa)
ABL2Tyrosine-protein kinase. (1096 aa)
NOXA1NADPH oxidase activator 1. (474 aa)
ARHGAP1Rho GTPase activating protein 1. (450 aa)
ARHGDIBUncharacterized protein. (200 aa)
RBM39RNA-binding protein 39 isoform a. (530 aa)
ARHGAP17Rho GTPase activating protein 17. (930 aa)
SLITRK3SLIT and NTRK like family member 3. (978 aa)
ARAP2ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2. (1735 aa)
CDC42EP1Cdc42 effector protein 1 isoform X1. (376 aa)
BAIAP2BAI1 associated protein 2. (575 aa)
ARHGAP15Rho GTPase activating protein 15. (497 aa)
SRGAP2Uncharacterized protein. (1087 aa)
ARHGAP32Rho GTPase activating protein 32. (2089 aa)
ABRABR activator of RhoGEF and GTPase. (964 aa)
PIK3R2Uncharacterized protein. (772 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
DEPDC1BDEP domain containing 1B. (725 aa)
FERMT2Fermitin family member 2. (776 aa)
NCKAP1LNCK associated protein 1 like. (1128 aa)
MCAMMelanoma cell adhesion molecule. (667 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (903 aa)
OPHN1Oligophrenin 1. (808 aa)
EMDLEM domain-containing protein. (400 aa)
ESYT1Extended synaptotagmin 1. (1109 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (217 aa)
VAV2Vav guanine nucleotide exchange factor 2. (879 aa)
YKT6Uncharacterized protein; Belongs to the synaptobrevin family. (221 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (204 aa)
NCF4Neutrophil cytosolic factor 4. (381 aa)
EPHA2Ephrin type-A receptor 2 isoform 1. (975 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
SLC1A5Amino acid transporter. (541 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
RACGAP1Rac GTPase activating protein 1. (634 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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