(13 nodes) Lewis blood group biosynthesis network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FUT7	Alpha-(1,3)-fucosyltransferase 7. (342 aa)
	LOC100513844	Glyco_tran_10_N domain-containing protein. (361 aa)
	B3GALT1	Hexosyltransferase. (326 aa)
	B3GALT4	Hexosyltransferase. (377 aa)
	FUT2	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity). (340 aa)
	FUT9	Fucosyltransferase 9. (390 aa)
	B3GALT2	Hexosyltransferase. (422 aa)
	ST3GAL4	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4; Belongs to the glycosyltransferase 29 family. (393 aa)
	LOC110255214	Glyco_trans_2-like domain-containing protein. (506 aa)
	FUT10	Fucosyltransferase 10. (543 aa)
	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (367 aa)
	ST3GAL3	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family. (374 aa)
	FUT11	Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. (493 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3GALT1	B3GALT2	ENSSSCP00000069132	ENSSSCP00000011513	Hexosyltransferase.	Hexosyltransferase.	0.901
B3GALT1	FUT2	ENSSSCP00000069132	ENSSSCP00000003406	Hexosyltransferase.	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	0.934
B3GALT1	LOC100513844	ENSSSCP00000069132	ENSSSCP00000062533	Hexosyltransferase.	Glyco_tran_10_N domain-containing protein.	0.908
B3GALT1	ST3GAL3	ENSSSCP00000069132	ENSSSCP00000045432	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.	0.922
B3GALT1	ST3GAL4	ENSSSCP00000069132	ENSSSCP00000016153	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4; Belongs to the glycosyltransferase 29 family.	0.903
B3GALT2	B3GALT1	ENSSSCP00000011513	ENSSSCP00000069132	Hexosyltransferase.	Hexosyltransferase.	0.901
B3GALT2	FUT2	ENSSSCP00000011513	ENSSSCP00000003406	Hexosyltransferase.	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	0.918
B3GALT2	FUT9	ENSSSCP00000011513	ENSSSCP00000004681	Hexosyltransferase.	Fucosyltransferase 9.	0.472
B3GALT2	LOC100513844	ENSSSCP00000011513	ENSSSCP00000062533	Hexosyltransferase.	Glyco_tran_10_N domain-containing protein.	0.921
B3GALT2	ST3GAL3	ENSSSCP00000011513	ENSSSCP00000045432	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.	0.933
B3GALT2	ST3GAL4	ENSSSCP00000011513	ENSSSCP00000016153	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4; Belongs to the glycosyltransferase 29 family.	0.943
FUT10	FUT2	ENSSSCP00000037351	ENSSSCP00000003406	Fucosyltransferase 10.	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	0.467
FUT2	B3GALT1	ENSSSCP00000003406	ENSSSCP00000069132	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	Hexosyltransferase.	0.934
FUT2	B3GALT2	ENSSSCP00000003406	ENSSSCP00000011513	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	Hexosyltransferase.	0.918
FUT2	FUT10	ENSSSCP00000003406	ENSSSCP00000037351	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	Fucosyltransferase 10.	0.467
FUT2	FUT7	ENSSSCP00000003406	ENSSSCP00000051918	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	Alpha-(1,3)-fucosyltransferase 7.	0.675
FUT2	FUT9	ENSSSCP00000003406	ENSSSCP00000004681	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	Fucosyltransferase 9.	0.965
FUT2	LOC100513844	ENSSSCP00000003406	ENSSSCP00000062533	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	Glyco_tran_10_N domain-containing protein.	0.986
FUT2	ST3GAL3	ENSSSCP00000003406	ENSSSCP00000045432	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.	0.938
FUT2	ST3GAL4	ENSSSCP00000003406	ENSSSCP00000016153	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4; Belongs to the glycosyltransferase 29 family.	0.931