14 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	IFN-ALPHA-15	Uncharacterized protein. (225 aa)
	USP18	USP domain-containing protein; Belongs to the peptidase C19 family. (376 aa)
	IFN-ALPHA-8	Uncharacterized protein. (226 aa)
	IFN-ALPHA-9	Interferon-alpha-9. (189 aa)
	IFNA1	Uncharacterized protein. (189 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	A0A5G2QZT5_PIG	Uncharacterized protein. (178 aa)
	STAT2	Signal transducer and activator of transcription 2; Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive [...] (900 aa)
	IFNB1	Interferon-beta-1. (186 aa)
	IFNAR2	Uncharacterized protein. (574 aa)
	JAK1	Tyrosine-protein kinase. (1154 aa)
	TYK2	Tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1226 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (612 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5G2QZT5_PIG	IFN-ALPHA-15	ENSSSCP00000067458	ENSSSCP00000047731	Uncharacterized protein.	Uncharacterized protein.	0.420
A0A5G2QZT5_PIG	IFN-ALPHA-8	ENSSSCP00000067458	ENSSSCP00000053795	Uncharacterized protein.	Uncharacterized protein.	0.420
A0A5G2QZT5_PIG	IFN-ALPHA-9	ENSSSCP00000067458	ENSSSCP00000063698	Uncharacterized protein.	Interferon-alpha-9.	0.420
A0A5G2QZT5_PIG	IFNA1	ENSSSCP00000067458	ENSSSCP00000063734	Uncharacterized protein.	Uncharacterized protein.	0.405
A0A5G2QZT5_PIG	IFNAR2	ENSSSCP00000067458	ENSSSCP00000031430	Uncharacterized protein.	Uncharacterized protein.	0.743
A0A5G2QZT5_PIG	IFNB1	ENSSSCP00000067458	ENSSSCP00000005550	Uncharacterized protein.	Interferon-beta-1.	0.454
A0A5G2QZT5_PIG	JAK1	ENSSSCP00000067458	ENSSSCP00000032415	Uncharacterized protein.	Tyrosine-protein kinase.	0.503
A0A5G2QZT5_PIG	PTPN1	ENSSSCP00000067458	ENSSSCP00000037956	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type.	0.400
A0A5G2QZT5_PIG	PTPN11	ENSSSCP00000067458	ENSSSCP00000064345	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.400
A0A5G2QZT5_PIG	PTPN6	ENSSSCP00000067458	ENSSSCP00000036336	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.400
A0A5G2QZT5_PIG	STAT2	ENSSSCP00000067458	ENSSSCP00000069374	Uncharacterized protein.	Signal transducer and activator of transcription 2; Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive [...]	0.501
A0A5G2QZT5_PIG	TYK2	ENSSSCP00000067458	ENSSSCP00000035640	Uncharacterized protein.	Tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.503
IFN-ALPHA-15	A0A5G2QZT5_PIG	ENSSSCP00000047731	ENSSSCP00000067458	Uncharacterized protein.	Uncharacterized protein.	0.420
IFN-ALPHA-15	IFN-ALPHA-8	ENSSSCP00000047731	ENSSSCP00000053795	Uncharacterized protein.	Uncharacterized protein.	0.404
IFN-ALPHA-15	IFN-ALPHA-9	ENSSSCP00000047731	ENSSSCP00000063698	Uncharacterized protein.	Interferon-alpha-9.	0.405
IFN-ALPHA-15	IFNA1	ENSSSCP00000047731	ENSSSCP00000063734	Uncharacterized protein.	Uncharacterized protein.	0.422
IFN-ALPHA-15	IFNAR2	ENSSSCP00000047731	ENSSSCP00000031430	Uncharacterized protein.	Uncharacterized protein.	0.637
IFN-ALPHA-15	IFNB1	ENSSSCP00000047731	ENSSSCP00000005550	Uncharacterized protein.	Interferon-beta-1.	0.551
IFN-ALPHA-15	JAK1	ENSSSCP00000047731	ENSSSCP00000032415	Uncharacterized protein.	Tyrosine-protein kinase.	0.688
IFN-ALPHA-15	PTPN1	ENSSSCP00000047731	ENSSSCP00000037956	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type.	0.400