STRINGSTRING
PGAM5 PGAM5 MAP1LC3B MAP1LC3B PARK7 PARK7 PINK1 PINK1 TOMM5 TOMM5 MAP1LC3A MAP1LC3A TUBB1 TUBB1 DYNLL1 DYNLL1 LOC100127131 LOC100127131 KXD1 KXD1 TOMM7 TOMM7 CETN1 CETN1 LOC100510930 LOC100510930 CSNK2B CSNK2B FUNDC1 FUNDC1 SRC SRC VIM VIM DYNC1I2 DYNC1I2 TUBB6 TUBB6 TUBA1A TUBA1A USP30 USP30 ATG12 ATG12 TOMM6 TOMM6 SQSTM1 SQSTM1 MFN2 MFN2 MTERF3 MTERF3 HDAC6 HDAC6 DYNC1LI2 DYNC1LI2 UBC UBC UBE2V1 UBE2V1 TOMM70 TOMM70 CSNK2A1 CSNK2A1 TOMM40 TOMM40 ARL13B ARL13B TOMM20 TOMM20 UBE2N UBE2N DYNLL2 DYNLL2 TOMM22 TOMM22 TUBA4A TUBA4A A0A5G2R693_PIG A0A5G2R693_PIG TUBAL3 TUBAL3 IFT88 IFT88 TUBB4B TUBB4B MFN1 MFN1 PEX5 PEX5 CSNK2A2 CSNK2A2 DYNC1LI1 DYNC1LI1 NBR1 NBR1 VDAC1 VDAC1 DYNC1I1 DYNC1I1 RPS27A RPS27A TUBA8 TUBA8 ULK1 ULK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (288 aa)
MAP1LC3BMicrotubule-associated protein 1 light chain 3 beta. (125 aa)
PARK7DJ-1 protein. (189 aa)
PINK1PTEN induced kinase 1. (588 aa)
TOMM5Mitochondrial import receptor subunit TOM5. (51 aa)
MAP1LC3AMicrotubule-associated protein 1 light chain 3 alpha. (121 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
DYNLL1Dynein light chain. (89 aa)
LOC100127131Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (474 aa)
KXD1Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (305 aa)
TOMM7Mitochondrial import receptor subunit TOM7 homolog; Required for assembly and stability of the TOM complex (By similarity). Positive regulator of PRKN translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria (By similarity). (55 aa)
CETN1Centrin 1. (168 aa)
LOC100510930Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (469 aa)
CSNK2BCasein kinase II subunit beta; Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). (298 aa)
FUNDC1FUN14 domain containing 1. (158 aa)
SRCTyrosine-protein kinase. (559 aa)
VIMVimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (469 aa)
DYNC1I2WD_REPEATS_REGION domain-containing protein. (581 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (411 aa)
TUBA1ADetyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (516 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
TOMM6Translocase of outer mitochondrial membrane 6. (74 aa)
SQSTM1Sequestosome 1. (451 aa)
MFN2Mitofusin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
MTERF3Transcription termination factor 3, mitochondrial isoform 1. (445 aa)
HDAC6Histone deacetylase 6. (1159 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
UBCUbiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (837 aa)
UBE2V1UBIQUITIN_CONJUGAT_2 domain-containing protein. (170 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (609 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (398 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (400 aa)
ARL13BADP ribosylation factor like GTPase 13B. (469 aa)
TOMM20Translocase of outer mitochondrial membrane 20. (152 aa)
UBE2NUbiquitin conjugating enzyme E2 N like (gene/pseudogene). (147 aa)
DYNLL2Dynein light chain. (133 aa)
TOMM22Uncharacterized protein. (207 aa)
TUBA4ATubulin alpha 4a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (618 aa)
A0A5G2R693_PIGTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (517 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
IFT88Intraflagellar transport 88. (817 aa)
TUBB4BTubulin beta 4B class IVb; Belongs to the tubulin family. (561 aa)
MFN1Mitochondrial mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (741 aa)
PEX5Peroxisomal biogenesis factor 5. (660 aa)
CSNK2A2Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. (350 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
NBR1Next to BRCA1 gene 1 protein isoform X1. (960 aa)
VDAC1Voltage-dependent anion-selective channel protein 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition p [...] (302 aa)
DYNC1I1Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (645 aa)
RPS27AUbiquitin-like domain-containing protein. (204 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (497 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1176 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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