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| | UFL1 | E3 UFM1-protein ligase 1. (792 aa) |
| | FBXO7 | F-box protein 7. (606 aa) |
| | KLHL42 | Kelch like family member 42. (505 aa) |
| | MYLIP | Myosin regulatory light chain interacting protein. (445 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | CUL7 | Cullin-7 isoform X6; Belongs to the cullin family. (1691 aa) |
| | BTBD1 | BTB/POZ domain-containing protein 1 isoform 1. (484 aa) |
| | HECTD1 | HECT domain E3 ubiquitin protein ligase 1. (2139 aa) |
| | PSME1 | Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). (284 aa) |
| | PSMB11 | Proteasome subunit beta. (291 aa) |
| | KLHL25 | Kelch like family member 25. (405 aa) |
| | PSMC1 | 26S proteasome regulatory subunit 4 isoform a; Belongs to the AAA ATPase family. (440 aa) |
| | FBXL8 | F-box domain-containing protein. (373 aa) |
| | UBR4 | Ubiquitin protein ligase E3 component n-recognin 4. (5180 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | RNF138 | Ring finger protein 138. (245 aa) |
| | LRRC41 | Leucine rich repeat containing 41. (812 aa) |
| | CDC20 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] (499 aa) |
| | FBXL4 | F-box and leucine-rich repeat protein 4. (621 aa) |
| | HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (912 aa) |
| | FBXO15 | F-box only protein 15 isoform 2. (514 aa) |
| | LRR1 | Leucine-rich repeat protein 1 isoform 1. (424 aa) |
| | TRIM9 | Tripartite motif containing 9. (710 aa) |
| | KLHL9 | Kelch like family member 9. (617 aa) |
| | TRIM32 | Tripartite motif containing 32. (652 aa) |
| | PSMB7 | Proteasome subunit beta type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...] (277 aa) |
| | LRSAM1 | Leucine rich repeat and sterile alpha motif containing 1. (737 aa) |
| | ASB6 | Ankyrin repeat and SOCS box containing 6. (425 aa) |
| | FBXW5 | F-box and WD repeat domain containing 5. (567 aa) |
| | UBE2Q1 | Ubiquitin conjugating enzyme E2 Q1. (511 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (380 aa) |
| | PSMA5 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (232 aa) |
| | LONRF1 | LON peptidase N-terminal domain and RING finger protein 1 isoform 1. (770 aa) |
| | RBCK1 | RanBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1. (510 aa) |
| | UBE2C | Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | TRIM4 | E3 ubiquitin-protein ligase TRIM4 isoform beta. (516 aa) |
| | FBXL16 | F-box and leucine rich repeat protein 16. (537 aa) |
| | TRAF7 | TNF receptor associated factor 7. (808 aa) |
| | ASB3 | Ankyrin repeat and SOCS box protein 3 isoform X1. (525 aa) |
| | FBXL5 | F-box and leucine rich repeat protein 5. (691 aa) |
| | KLHL2 | Kelch like family member 2. (593 aa) |
| | HERC3 | Uncharacterized protein. (1050 aa) |
| | SH3RF1 | E3 ubiquitin-protein ligase SH3RF1 isoform X1. (849 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5 isoform X1. (755 aa) |
| | FBXO21 | F-box protein 21. (613 aa) |
| | KLHL22 | Kelch like family member 22. (634 aa) |
| | FBXW4 | F-box and WD repeat domain containing 4. (630 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (450 aa) |
| | KBTBD8 | Kelch repeat and BTB domain-containing protein 8 isoform X1. (601 aa) |
| | VHL | Von Hippel-Lindau disease tumor suppressor isoform 1. (205 aa) |
| | FBXO40 | F-box only protein 40. (706 aa) |
| | ASB11 | Ankyrin repeat and SOCS box containing 11. (323 aa) |
| | UBA1 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1018 aa) |
| | HUWE1 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4415 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (458 aa) |
| | KXD1 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (305 aa) |
| | FBXL21P | F-box domain-containing protein. (420 aa) |
| | CDC23 | Cell division cycle protein 23 homolog. (594 aa) |
| | RNF14 | RBR-type E3 ubiquitin transferase. (474 aa) |
| | TRIM21 | Tripartite motif containing 21. (474 aa) |
| | ASB4 | Ankyrin repeat and SOCS box protein 4 isoform a. (426 aa) |
| | PSMC2 | AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa) |
| | HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4852 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | UBE3C | Ubiquitin protein ligase E3C. (1084 aa) |
| | UBE2D4 | Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (166 aa) |
| | SKP2 | S-phase kinase-associated protein 2 isoform 1. (436 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (534 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (421 aa) |
| | BLMH | Bleomycin hydrolase; Belongs to the peptidase C1 family. (454 aa) |
| | TRIM63 | Uncharacterized protein. (356 aa) |
| | ASB10 | Ankyrin repeat and SOCS box protein 10 isoform 1. (465 aa) |
| | PJA2 | Praja ring finger ubiquitin ligase 2. (720 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (597 aa) |
| | LTN1 | Listerin E3 ubiquitin protein ligase 1. (1731 aa) |
| | RNF217 | RBR-type E3 ubiquitin transferase. (541 aa) |
| | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5. (968 aa) |
| | PJA1 | E3 ubiquitin-protein ligase Praja-1 isoform X1. (635 aa) |
| | RNF25 | Ring finger protein 25. (459 aa) |
| | ASB5 | Ankyrin repeat and SOCS box containing 5. (347 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) |
| | CUL5 | Cullin-5; Belongs to the cullin family. (780 aa) |
| | PSMF1 | Uncharacterized protein. (351 aa) |
| | RNF6 | Ring finger protein 6. (663 aa) |
| | HECTD2 | HECT domain E3 ubiquitin protein ligase 2. (776 aa) |
| | FBXO10 | F-box protein 10. (952 aa) |
| | UBE2G2 | Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (202 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (220 aa) |
| | TRAIP | E3 ubiquitin-protein ligase TRAIP. (471 aa) |
| | CBLL1 | Cbl proto-oncogene like 1. (529 aa) |
| | KCTD6 | Potassium channel tetramerization domain containing 6. (261 aa) |
| | UBE2L6 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (168 aa) |
| | FBXL19 | F-box and leucine rich repeat protein 19. (694 aa) |
| | RNF7 | Ring finger protein 7. (113 aa) |
| | ASB8 | Ankyrin repeat and SOCS box protein 8 isoform a. (288 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (737 aa) |
| | UBE2Z | Ubiquitin-conjugating enzyme E2 Z. (356 aa) |
| | FBXL7 | F-box and leucine rich repeat protein 7. (491 aa) |
| | DET1 | Uncharacterized protein. (550 aa) |
| | ASB9 | Ankyrin repeat and SOCS box protein 9 isoform 2. (263 aa) |
| | UBE2E2 | Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa) |
| | TRIM37 | Tripartite motif containing 37. (992 aa) |
| | RNF123 | Ring finger protein 123. (1343 aa) |
| | ASB15 | Ankyrin repeat and SOCS box containing 15. (613 aa) |
| | SPSB1 | SplA/ryanodine receptor domain and SOCS box containing 1. (273 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | FBXL3 | F-box and leucine rich repeat protein 3. (429 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (802 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | RBBP6 | RB binding protein 6, ubiquitin ligase. (1794 aa) |
| | MEX3C | RNA-binding E3 ubiquitin-protein ligase MEX3C. (655 aa) |
| | UBE2D2 | Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (146 aa) |
| | UBR1 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1753 aa) |
| | RNF19A | E3 ubiquitin-protein ligase RNF19A; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR; Belongs to the RBR family. RNF19 subfamily. (838 aa) |
| | A0A286ZS34_PIG | Uncharacterized protein. (179 aa) |
| | FBXW2 | F-box domain-containing protein. (234 aa) |
| | ASB17 | Ankyrin repeat and SOCS box containing 17. (295 aa) |
| | RNF34 | E3 ubiquitin-protein ligase RNF34 isoform 2. (383 aa) |
| | WSB1 | WD repeat and SOCS box-containing protein 1 isoform 1. (421 aa) |
| | SIAH1 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa) |
| | LMO7 | LIM domain 7. (1598 aa) |
| | KLHL11 | Kelch like family member 11. (744 aa) |
| | A0A286ZW56_PIG | Uncharacterized protein. (277 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1944 aa) |
| | CDC26 | Cell division cycle 26. (107 aa) |
| | RNF144B | RBR-type E3 ubiquitin transferase. (333 aa) |
| | FBXL12 | F-box and leucine rich repeat protein 12. (411 aa) |
| | RNF4 | E3 ubiquitin-protein ligase RNF4 isoform 1. (190 aa) |
| | ANAPC13 | Anaphase-promoting complex subunit 13. (74 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 isoform 1. (456 aa) |
| | RNF41 | E3 ubiquitin-protein ligase NRDP1 isoform 1. (317 aa) |
| | KBTBD7 | Kelch repeat and BTB domain containing 7. (641 aa) |
| | ASB2 | Ankyrin repeat and SOCS box containing 2. (607 aa) |
| | FBXL14 | F-box and leucine rich repeat protein 14. (375 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (773 aa) |
| | UBR2 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa) |
| | FBXL13 | F-box and leucine rich repeat protein 13. (737 aa) |
| | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 isoform 1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | UBE2U | Ubiquitin conjugating enzyme E2 U; Belongs to the ubiquitin-conjugating enzyme family. (309 aa) |
| | BTBD6 | BTB domain containing 6. (538 aa) |
| | FBXO41 | F-box protein 41. (874 aa) |
| | HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1095 aa) |
| | UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (876 aa) |
| | FBXO2 | F-box protein 2. (322 aa) |
| | TRIM36 | Tripartite motif containing 36. (729 aa) |
| | KLHL20 | Kelch like family member 20. (788 aa) |
| | UBE2H | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa) |
| | RNF19B | RBR-type E3 ubiquitin transferase. (732 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (873 aa) |
| | UBE2J1 | Ubiquitin-conjugating enzyme E2 J1. (318 aa) |
| | KLHL13 | Kelch like family member 13. (692 aa) |
| | KLHL41 | Kelch like family member 41. (601 aa) |
| | TRIM41 | E3 ubiquitin-protein ligase TRIM41 isoform 1. (629 aa) |
| | KBTBD13 | Kelch repeat and BTB domain containing 13. (455 aa) |
| | CCNF | Cyclin F; Belongs to the cyclin family. (788 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (710 aa) |
| | TPP2 | Tripeptidyl peptidase 2. (1263 aa) |
| | UBE2B | Ubiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | SPSB2 | Uncharacterized protein. (263 aa) |
| | UBE3B | Ubiquitin protein ligase E3B. (1088 aa) |
| | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6. (1021 aa) |
| | TRIM11 | E3 ubiquitin-protein ligase TRIM11. (468 aa) |
| | PSME4 | Proteasome activator complex subunit 4. (1843 aa) |
| | AREL1 | Apoptosis resistant E3 ubiquitin protein ligase 1. (827 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa) |
| | MKRN1 | E3 ubiquitin-protein ligase makorin-1 isoform X1. (482 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (748 aa) |
| | UBE2K | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (157 aa) |
| | CBLB | E3 ubiquitin-protein ligase CBL-B isoform X1. (1047 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1511 aa) |
| | UNKL | Uncharacterized protein. (758 aa) |
| | UBA7 | Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1012 aa) |
| | FBXW8 | F-box and WD repeat domain containing 8. (596 aa) |
| | RLIM | Ring finger protein, LIM domain interacting. (623 aa) |
| | RNF114 | E3 ubiquitin-protein ligase RNF114; E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates. In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity. Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3. May promote the ubiquitination of TRAF6 as well. Acts also as a negative regulator of T-cell activation. Inhibits cellular dsRNA responses and interferon produ [...] (228 aa) |
| | CDRT1 | WD_REPEATS_REGION domain-containing protein. (1077 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (204 aa) |
| | UBE3D | Ubiquitin protein ligase E3D. (395 aa) |
| | ZNRF2 | Zinc and ring finger 2. (240 aa) |
| | RNF115 | E3 ubiquitin-protein ligase RNF115. (293 aa) |
| | UBE2R2 | Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa) |
| | TRIM71 | E3 ubiquitin-protein ligase TRIM71. (869 aa) |
| | MGRN1 | Mahogunin ring finger 1. (571 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (493 aa) |
| | RNF126 | Ring finger protein 126. (312 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | ASB13 | Ankyrin repeat and SOCS box containing 13. (331 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (108 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (351 aa) |
| | KLHL3 | Kelch like family member 3. (601 aa) |
| | RNF111 | Ring finger protein 111. (992 aa) |
| | UBE2E3 | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (229 aa) |
| | A0A287B6X8_PIG | RING-type domain-containing protein. (509 aa) |
| | ARIH2 | RBR-type E3 ubiquitin transferase. (491 aa) |
| | UBE2O | Ubiquitin conjugating enzyme E2 O. (1296 aa) |
| | SPSB4 | SplA/ryanodine receptor domain and SOCS box containing 4. (272 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (882 aa) |
| | ASB14 | Ankyrin repeat and SOCS box protein 14 isoform 1. (584 aa) |
| | FBXO30 | F-box protein 30. (949 aa) |
| | UBE2W | UBIQUITIN_CONJUGAT_2 domain-containing protein. (180 aa) |
| | FBXO17 | F-box protein 17. (295 aa) |
| | TRIP12 | Thyroid hormone receptor interactor 12. (2026 aa) |
| | KBTBD6 | Kelch repeat and BTB domain-containing protein 6. (695 aa) |
| | LOC102160336 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (206 aa) |
| | ASB12 | Ankyrin repeat and SOCS box containing 12. (318 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (481 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (303 aa) |
| | LNX1 | E3 ubiquitin-protein ligase LNX isoform X1. (733 aa) |
| | CDC27 | Cell division cycle 27. (825 aa) |
| | NEDD4 | E3 ubiquitin-protein ligase NEDD4 isoform 3. (1323 aa) |
| | KEAP1 | Kelch-like ECH-associated protein 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination. KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine [...] (624 aa) |
| | FBXO32 | F-box only protein 32; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity). (425 aa) |
| | UBOX5 | U-box domain containing 5. (541 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) |
| | HECTD3 | HECT domain E3 ubiquitin protein ligase 3. (853 aa) |
| | UBE2M | Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (215 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | CDC34 | Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (234 aa) |
| | FBXO22 | F-box only protein 22 isoform a. (404 aa) |
| | PSMB10 | Proteasome subunit beta. (296 aa) |
| | PSMA7 | Proteasome subunit alpha type. (267 aa) |
| | FBXO6 | Uncharacterized protein. (282 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | WWP1 | E3 ubiquitin-protein ligase. (923 aa) |
| | RNF182 | E3 ubiquitin-protein ligase RNF182. (247 aa) |
| | GAN | Gigaxonin. (597 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 isoform 1. (504 aa) |
| | UBE2F | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (250 aa) |
| | KLHL21 | Kelch like family member 21. (598 aa) |
| | UBA3 | Ubiquitin like modifier activating enzyme 3. (514 aa) |
| | UBC | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (837 aa) |
| | UBA5 | Ubiquitin like modifier activating enzyme 5. (447 aa) |
| | UBE2J2 | Ubiquitin-conjugating enzyme E2 J2. (259 aa) |
| | UBE4A | U-box domain-containing protein. (1074 aa) |
| | PSMA2 | Proteasome endopeptidase complex. (243 aa) |
| | UBE2V2 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (159 aa) |
| | UBE2V1 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (170 aa) |
| | GLMN | Glomulin, FKBP associated protein. (613 aa) |
| | PSMC5 | 26S proteasome regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (435 aa) |
| | FBXL20 | F-box and leucine rich repeat protein 20. (456 aa) |
| | ANAPC11 | RING-type domain-containing protein. (411 aa) |
| | LNPEP | Uncharacterized protein. (1120 aa) |
| | PSMA4 | Proteasome subunit alpha type. (281 aa) |
| | UBE2L3 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (227 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PSMA3 | Proteasome subunit alpha type. (275 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (419 aa) |
| | TRIM39 | E3 ubiquitin-protein ligase TRIM39 isoform 2. (488 aa) |
| | FBXO31 | F-box only protein 31 isoform X1. (566 aa) |
| | NEDD4L | NEDD4 like E3 ubiquitin protein ligase. (1265 aa) |
| | RNF220 | Ring finger protein 220. (565 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (629 aa) |
| | FBXO11 | F-box protein 11. (946 aa) |
| | UBE2A | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (224 aa) |
| | FBXL18 | F-box and leucine rich repeat protein 18. (735 aa) |
| | MIB2 | Mindbomb E3 ubiquitin protein ligase 2. (1065 aa) |
| | ASB7 | Ankyrin repeat and SOCS box containing 7. (360 aa) |
| | FBXO4 | F-box only protein 4. (387 aa) |
| | ELOC | Elongin C; Belongs to the SKP1 family. (139 aa) |
| | KCTD7 | Potassium channel tetramerization domain containing 7. (305 aa) |
| | PSMB6 | Uncharacterized protein. (334 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (859 aa) |
| | RCHY1 | Ring finger and CHY zinc finger domain containing 1. (299 aa) |
| | NPEPPS | Aminopeptidase. (944 aa) |
| | ASB18 | Ankyrin repeat and SOCS box containing 18. (437 aa) |
| | UBAC1 | UBA domain containing 1. (497 aa) |
| | UBE2N | Ubiquitin conjugating enzyme E2 N like (gene/pseudogene). (147 aa) |
| | KLHL5 | Kelch like family member 5. (754 aa) |
| | DZIP3 | DAZ interacting zinc finger protein 3. (1245 aa) |
| | FBXO9 | F-box domain-containing protein. (448 aa) |
| | CDC16 | TPR_REGION domain-containing protein. (680 aa) |
| | ELOB | Elongin B. (140 aa) |
| | PSME3 | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (265 aa) |
| | ASB1 | Ankyrin repeat and SOCS box containing 1. (463 aa) |
| | TRIM69 | Tripartite motif containing 69. (500 aa) |
| | CUL2 | Cullin 2; Belongs to the cullin family. (746 aa) |
