STRINGSTRING
RCOR1 RCOR1 KLC1 KLC1 KDM1A KDM1A KIF2C KIF2C F1SBY7_PIG F1SBY7_PIG MICAL1 MICAL1 HDAC2 HDAC2 KIF23 KIF23 ZFPM2 ZFPM2 VPS45 VPS45 CAPZA1 CAPZA1 TUBB1 TUBB1 GATA5 GATA5 MAFK MAFK SH2B1 SH2B1 DOCK5 DOCK5 KIF13B KIF13B SH2B3 SH2B3 JMJD1C JMJD1C KIF11 KIF11 KIF5B KIF5B LOC100127131 LOC100127131 GATA2 GATA2 DOCK11 DOCK11 EHD1 EHD1 KIF18A KIF18A DOCK10 DOCK10 DOCK2 DOCK2 LOC100521680 LOC100521680 KIF2B KIF2B KIF1C KIF1C HDAC1 HDAC1 EHD2 EHD2 LOC100510930 LOC100510930 GATA1 GATA1 KIF19 KIF19 KIF16B KIF16B KIF2A KIF2A RAD51C RAD51C MAFF MAFF KIF22 KIF22 KIF27 KIF27 KIF26B KIF26B GATA4 GATA4 JAK2 JAK2 SH2B2 SH2B2 CDC42 CDC42 DOCK7 DOCK7 PRKAR2B PRKAR2B A0A286ZRB3_PIG A0A286ZRB3_PIG RAB5A RAB5A NFE2 NFE2 CARMIL1 CARMIL1 DOCK8 DOCK8 TUBB4B TUBB4B DOCK1 DOCK1 MFN1 MFN1 GATA3 GATA3 PHF21A PHF21A CBX5 CBX5 KIFC2 KIFC2 DOCK3 DOCK3 KIF3B KIF3B HMG20B HMG20B KIF12 KIF12 KIF4A KIF4A DOCK9 DOCK9 RBSN RBSN KIF20B KIF20B ZFPM1 ZFPM1 EHD3 EHD3 ITPK1 ITPK1 TUBA8 TUBA8 DOCK6 DOCK6 TUBB6 TUBB6 TUBA1A TUBA1A KIFAP3 KIFAP3 CENPE CENPE KIF3C KIF3C MAFG MAFG HIST1H3E HIST1H3E KIF1B KIF1B KIF20A KIF20A KIF15 KIF15 DOCK4 DOCK4 MFN2 MFN2 AKAP1 AKAP1 PRKAR1B PRKAR1B RAC1 RAC1 KIF9 KIF9 CAPZA2 CAPZA2 AK3 AK3 KIF1A KIF1A KIF26A KIF26A KIF18B KIF18B KLC3 KLC3 KIF3A KIF3A TUBA4A TUBA4A A0A5G2R693_PIG A0A5G2R693_PIG RAD51B RAD51B KIF21A KIF21A TUBAL3 TUBAL3 KLC2 KLC2 KLC4 KLC4 KIF6 KIF6 KIFC1 KIFC1 KIF5A KIF5A RACGAP1 RACGAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RCOR1REST corepressor 1. (487 aa)
KLC1Uncharacterized protein. (677 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (875 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
F1SBY7_PIGKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (442 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1122 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (967 aa)
ZFPM2Uncharacterized protein. (1153 aa)
VPS45Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (570 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (294 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
GATA5GATA binding protein 5. (393 aa)
MAFKMAF bZIP transcription factor K. (156 aa)
SH2B1SH2B adaptor protein 1. (757 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1867 aa)
KIF13BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (741 aa)
SH2B3SH2B adaptor protein 3. (600 aa)
JMJD1CJumonji domain containing 1C. (2591 aa)
KIF11Kinesin-like protein KIF11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1059 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
LOC100127131Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (474 aa)
GATA2GATA binding protein 2. (502 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2056 aa)
EHD1EH domain containing 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (564 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (904 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2201 aa)
DOCK2Dedicator of cytokinesis protein 2; Belongs to the DOCK family. (1827 aa)
LOC100521680Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (684 aa)
KIF1CKinesin family member 1C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1101 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
LOC100510930Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (469 aa)
GATA1Erythroid transcription factor. (412 aa)
KIF19Kinesin-like protein KIF19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1001 aa)
KIF16BKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1879 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
RAD51CRAD51 paralog C. (371 aa)
MAFFMAF bZIP transcription factor F. (166 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (753 aa)
KIF27Kinesin family member 27; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1401 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2109 aa)
GATA4Transcription factor GATA-4 isoform 2. (442 aa)
JAK2Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN- beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors [...] (1131 aa)
SH2B2SH2B adaptor protein 2. (695 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2312 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (468 aa)
A0A286ZRB3_PIGHistone domain-containing protein. (130 aa)
RAB5ARas-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] (215 aa)
NFE2Nuclear factor, erythroid 2. (373 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1429 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (1998 aa)
TUBB4BTubulin beta 4B class IVb; Belongs to the tubulin family. (561 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1828 aa)
MFN1Mitochondrial mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (741 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (444 aa)
PHF21APHD finger protein 21A. (689 aa)
CBX5Chromobox protein homolog 5. (191 aa)
KIFC2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (873 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2071 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
HMG20BHigh mobility group 20B. (357 aa)
KIF12Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (651 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1195 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2290 aa)
RBSNRabenosyn, RAB effector. (761 aa)
KIF20BKinesin-like protein KIF20B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1787 aa)
ZFPM1Zinc finger protein, FOG family member 1. (965 aa)
EHD3EH domain-containing protein 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (460 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (497 aa)
DOCK6Dedicator of cytokinesis 6; Belongs to the DOCK family. (2123 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (411 aa)
TUBA1ADetyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
KIFAP3Kinesin-associated protein 3 isoform X1. (809 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2733 aa)
KIF3CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (798 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
HIST1H3EHistone H3; Belongs to the histone H3 family. (136 aa)
KIF1BKinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1816 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
KIF15Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1395 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1977 aa)
MFN2Mitofusin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
AKAP1Tudor domain-containing protein. (871 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (454 aa)
RAC1Rac family small GTPase 1. (186 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (885 aa)
CAPZA2F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (286 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa)
KIF1AKinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1793 aa)
KIF26AKinesin family member 26A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1867 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (859 aa)
KLC3Kinesin light chain 3. (549 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (754 aa)
TUBA4ATubulin alpha 4a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (618 aa)
A0A5G2R693_PIGTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (517 aa)
RAD51BRAD51 paralog B. (365 aa)
KIF21AKinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1673 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
KLC2Ras-related protein Rab-1B. (865 aa)
KLC4Kinesin light chain 4 isoform X1. (616 aa)
KIF6Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (483 aa)
KIFC1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (704 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1085 aa)
RACGAP1Rac GTPase activating protein 1. (634 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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