STRINGSTRING
ALG12 ALG12 FUT8 FUT8 MAN1A1 MAN1A1 ALG2 ALG2 DOLK DOLK B4GALT3 B4GALT3 ALG1 ALG1 MGAT4A MGAT4A MOGS MOGS ALG5 ALG5 ALG11 ALG11 STT3B STT3B MGAT1 MGAT1 DPAGT1 DPAGT1 MGAT5B MGAT5B LOC100525350 LOC100525350 MAN1C1 MAN1C1 ALG10 ALG10 ALG3 ALG3 RPN2 RPN2 ST6GAL1 ST6GAL1 ALG6 ALG6 MGAT5 MGAT5 MAN1B1 MAN1B1 DDOST DDOST LOC100514465 LOC100514465 MGAT4C MGAT4C GANAB GANAB DPM2 DPM2 MGAT4D MGAT4D TUSC3 TUSC3 B4GALT1 B4GALT1 ALG14 ALG14 DPM1 DPM1 B4GALT2 B4GALT2 RPN1 RPN1 STT3A STT3A MGAT3 MGAT3 ALG8 ALG8 MGAT2 MGAT2 DOLPP1 DOLPP1 DAD1 DAD1 MGAT4B MGAT4B MAN2A1 MAN2A1 ST6GAL2 ST6GAL2 ALG9 ALG9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALG12Mannosyltransferase. (505 aa)
FUT8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. (581 aa)
MAN1A1Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). (837 aa)
ALG2ALG2 alpha-1,3/1,6-mannosyltransferase. (416 aa)
DOLKDolichol kinase. (531 aa)
B4GALT3Beta-1,4-galactosyltransferase 3. (402 aa)
ALG1Chitobiosyldiphosphodolichol beta-mannosyltransferase isoform 1. (468 aa)
MGAT4AAlpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A. (568 aa)
MOGSMannosyl-oligosaccharide glucosidase isoform 1. (839 aa)
ALG5Glyco_trans_2-like domain-containing protein. (323 aa)
ALG11ALG11 alpha-1,2-mannosyltransferase. (492 aa)
STT3BSTT3 oligosaccharyltransferase complex catalytic subunit B. (825 aa)
MGAT1Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (447 aa)
DPAGT1UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase. (408 aa)
MGAT5BAlpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform 3. (792 aa)
LOC100525350S5A_REDUCTASE domain-containing protein. (318 aa)
MAN1C1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (627 aa)
ALG10Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase. (478 aa)
ALG3Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol. (438 aa)
RPN2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (654 aa)
ST6GAL1ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (408 aa)
ALG6Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (679 aa)
MGAT5Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (741 aa)
MAN1B1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (652 aa)
DDOSTDolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (437 aa)
LOC100514465Uncharacterized protein. (371 aa)
MGAT4CAlpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; Glycosyltransferase that participates in the transfer of N- acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity) (By similarity). (477 aa)
GANABNeutral alpha-glucosidase AB; Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia. (978 aa)
DPM2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (84 aa)
MGAT4DMGAT4 family member D. (379 aa)
TUSC3Tumor suppressor candidate 3. (348 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (401 aa)
ALG14UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform 1. (216 aa)
DPM1Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex. (259 aa)
B4GALT2Beta-1,4-galactosyltransferase 2. (397 aa)
RPN1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (Probable). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation ac [...] (677 aa)
STT3ASTT3 oligosaccharyltransferase complex catalytic subunit A. (786 aa)
MGAT3Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase. (622 aa)
ALG8Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (574 aa)
MGAT2Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Plays an essential role in protein N-glycosylation. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) onto the free terminal mannose moiety in the core structure of the nascent N-linked glycan chain, giving rise to the second branch in complex glycans. Belongs to the glycosyltransferase 16 (GT16) protein family. (487 aa)
DOLPP1Dolichyldiphosphatase 1. (240 aa)
DAD1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
MGAT4BAlpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B. (554 aa)
MAN2A1Alpha-mannosidase. (1164 aa)
ST6GAL2Beta-galactoside alpha-2,6-sialyltransferase 2 isoform a; Belongs to the glycosyltransferase 29 family. (503 aa)
ALG9Mannosyltransferase. (641 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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