(20 nodes) Terpenoid backbone biosynthesis network (Sus scrofa)

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	FNTB	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. (437 aa)
	FDPS	Farnesyl pyrophosphate synthase isoform X1; Belongs to the FPP/GGPP synthase family. (421 aa)
	PMVK	Phosphomevalonate kinase. (192 aa)
	HMGCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (576 aa)
	PCYOX1	Prenylcysteine oxidase 1. (513 aa)
	NUS1	NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa)
	IDI1	Isopentenyl-diphosphate delta isomerase 1. (227 aa)
	ACAT1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	HMGCS2	Hydroxymethylglutaryl-CoA synthase, mitochondrial; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase; Belongs to the thiolase-like superfamily. HMG-CoA synthase family. (508 aa)
	ICMT	Protein-S-isoprenylcysteine O-methyltransferase. (481 aa)
	MVD	Mevalonate diphosphate decarboxylase. (474 aa)
	RCE1	Ras converting CAAX endopeptidase 1. (482 aa)
	DHDDS	Alkyl transferase; Belongs to the UPP synthase family. (333 aa)
	FNTA	Farnesyltransferase, CAAX box, alpha. (368 aa)
	GGPS1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (300 aa)
	ACAT2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (447 aa)
	PDSS2	Decaprenyl-diphosphate synthase subunit 2 isoform X1; Belongs to the FPP/GGPP synthase family. (394 aa)
	PDSS1	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (409 aa)
	HMGCR	3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins. (887 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAT1	ACAT2	ENSSSCP00000025827	ENSSSCP00000047700	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.919
ACAT1	HMGCS1	ENSSSCP00000025827	ENSSSCP00000017880	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.991
ACAT1	HMGCS2	ENSSSCP00000025827	ENSSSCP00000034427	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxymethylglutaryl-CoA synthase, mitochondrial; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase; Belongs to the thiolase-like superfamily. HMG-CoA synthase family.	0.991
ACAT1	MVD	ENSSSCP00000025827	ENSSSCP00000037983	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Mevalonate diphosphate decarboxylase.	0.543
ACAT2	ACAT1	ENSSSCP00000047700	ENSSSCP00000025827	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.919
ACAT2	FDPS	ENSSSCP00000047700	ENSSSCP00000006940	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Farnesyl pyrophosphate synthase isoform X1; Belongs to the FPP/GGPP synthase family.	0.578
ACAT2	HMGCR	ENSSSCP00000047700	ENSSSCP00000053515	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.	0.528
ACAT2	HMGCS1	ENSSSCP00000047700	ENSSSCP00000017880	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.992
ACAT2	HMGCS2	ENSSSCP00000047700	ENSSSCP00000034427	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxymethylglutaryl-CoA synthase, mitochondrial; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase; Belongs to the thiolase-like superfamily. HMG-CoA synthase family.	0.987
ACAT2	IDI1	ENSSSCP00000047700	ENSSSCP00000025683	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Isopentenyl-diphosphate delta isomerase 1.	0.493
ACAT2	MVD	ENSSSCP00000047700	ENSSSCP00000037983	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Mevalonate diphosphate decarboxylase.	0.555
DHDDS	FDPS	ENSSSCP00000040853	ENSSSCP00000006940	Alkyl transferase; Belongs to the UPP synthase family.	Farnesyl pyrophosphate synthase isoform X1; Belongs to the FPP/GGPP synthase family.	0.954
DHDDS	FNTA	ENSSSCP00000040853	ENSSSCP00000044084	Alkyl transferase; Belongs to the UPP synthase family.	Farnesyltransferase, CAAX box, alpha.	0.987
DHDDS	FNTB	ENSSSCP00000040853	ENSSSCP00000002475	Alkyl transferase; Belongs to the UPP synthase family.	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.	0.931
DHDDS	GGPS1	ENSSSCP00000040853	ENSSSCP00000046619	Alkyl transferase; Belongs to the UPP synthase family.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.951
DHDDS	HMGCR	ENSSSCP00000040853	ENSSSCP00000053515	Alkyl transferase; Belongs to the UPP synthase family.	3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.	0.413
DHDDS	IDI1	ENSSSCP00000040853	ENSSSCP00000025683	Alkyl transferase; Belongs to the UPP synthase family.	Isopentenyl-diphosphate delta isomerase 1.	0.857
DHDDS	MVD	ENSSSCP00000040853	ENSSSCP00000037983	Alkyl transferase; Belongs to the UPP synthase family.	Mevalonate diphosphate decarboxylase.	0.409
DHDDS	NUS1	ENSSSCP00000040853	ENSSSCP00000025095	Alkyl transferase; Belongs to the UPP synthase family.	NUS1 dehydrodolichyl diphosphate synthase subunit.	0.991
DHDDS	PDSS1	ENSSSCP00000040853	ENSSSCP00000051289	Alkyl transferase; Belongs to the UPP synthase family.	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.	0.950