STRINGSTRING
SKIV2L SKIV2L WDR61 WDR61 EDC3 EDC3 EXOSC6 EXOSC6 EDC4 EDC4 EXOSC5 EXOSC5 EXOSC10 EXOSC10 PNLDC1 PNLDC1 DIS3L DIS3L ZCCHC7 ZCCHC7 EXOSC3 EXOSC3 EXOSC4 EXOSC4 PABPC1L PABPC1L PAN3 PAN3 ENO4 ENO4 EXOSC7 EXOSC7 DCP2 DCP2 BTG4 BTG4 DCPS DCPS MTREX MTREX TENT4A TENT4A PABPC1L2A-2 PABPC1L2A-2 ENO2 ENO2 DCP1B DCP1B DCP1A DCP1A CNOT1 CNOT1 DHX36 DHX36 PABPC1 PABPC1 PFKM PFKM LSM6 LSM6 A0A286ZMZ7_PIG A0A286ZMZ7_PIG XRN2 XRN2 EXOSC9 EXOSC9 ENO3 ENO3 BTG1 BTG1 CNOT7 CNOT7 PAN2 PAN2 HSPA9 HSPA9 CNOT3 CNOT3 MPHOSPH6 MPHOSPH6 PFKL PFKL PNPT1 PNPT1 NUDT16 NUDT16 DDX6 DDX6 ENO1 ENO1 HSPD1 HSPD1 PATL1 PATL1 CNOT2 CNOT2 PABPC5 PABPC5 CNOT4 CNOT4 LSM2 LSM2 TTC37 TTC37 TOB2 TOB2 C1D C1D PABPC4 PABPC4 EXOSC8 EXOSC8 DIS3 DIS3 CNOT6 CNOT6 LSM4 LSM4 CNOT8 CNOT8 XRN1 XRN1 LSM8 LSM8 BTG3 BTG3 LSM7 LSM7 LSM5 LSM5 PARN PARN CNOT10 CNOT10 CNOT9 CNOT9 LSM3 LSM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SKIV2LSki2 like RNA helicase. (1246 aa)
WDR61WD repeat-containing protein 61 isoform a. (305 aa)
EDC3Enhancer of mRNA decapping 3. (508 aa)
EXOSC6Exosome component 6. (272 aa)
EDC4Enhancer of mRNA decapping 4. (1402 aa)
EXOSC5Exosome component 5. (299 aa)
EXOSC10Exosome component 10. (869 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (531 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1054 aa)
ZCCHC7Zinc finger CCHC-type containing 7. (545 aa)
EXOSC3Exosome complex component RRP40 isoform 1. (275 aa)
EXOSC4Exosome complex component RRP41. (245 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (610 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (906 aa)
ENO4Enolase 4. (617 aa)
EXOSC7Uncharacterized protein. (349 aa)
DCP2Decapping mRNA 2. (478 aa)
BTG4BTG anti-proliferation factor 4. (225 aa)
DCPSm7GpppX diphosphatase; Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7- methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not h [...] (337 aa)
MTREXExosome RNA helicase MTR4. (1042 aa)
TENT4ATerminal nucleotidyltransferase 4A. (796 aa)
PABPC1L2A-2Uncharacterized protein. (457 aa)
ENO2Enolase 2. (434 aa)
DCP1BDecapping mRNA 1B. (559 aa)
DCP1AmRNA-decapping enzyme 1A; Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1; Belongs to the DCP1 family. (580 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2343 aa)
DHX36DEAH (Asp-Glu-Ala-His) box polypeptide 36 tv1. (1012 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
PFKMATP-dependent 6-phosphofructokinase, muscle type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (810 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (124 aa)
A0A286ZMZ7_PIGUncharacterized protein. (142 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (930 aa)
EXOSC9Exosome component 9. (455 aa)
ENO3Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. (476 aa)
BTG1B-cell translocation protein 1. (171 aa)
CNOT7CCR4-NOT transcription complex subunit 7 isoform 1. (285 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1198 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (774 aa)
MPHOSPH6M-phase phosphoprotein 6. (176 aa)
PFKL6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (782 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (784 aa)
NUDT16Nudix hydrolase 16. (211 aa)
DDX6Putative ATP-dependent RNA helicase DDX6 isoform X1; Belongs to the DEAD box helicase family. (483 aa)
ENO1Alpha-enolase isoform X1. (434 aa)
HSPD1Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (468 aa)
PATL1PAT1 homolog 1, processing body mRNA decay factor. (786 aa)
CNOT2NOT2_3_5 domain-containing protein. (578 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (710 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
TTC37Tetratricopeptide repeat protein 37 isoform X1. (1563 aa)
TOB2Protein Tob2 isoform X1. (353 aa)
C1DUncharacterized protein. (141 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
EXOSC8Exosome component 8. (281 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (590 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (234 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (312 aa)
XRN15'-3' exoribonuclease 1. (1703 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (127 aa)
BTG3Protein BTG3; Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase. (252 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (150 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (92 aa)
PARNPoly(A)-specific ribonuclease. (715 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (803 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (300 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (105 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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