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CLPS | Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. (112 aa) | ||||
ABCA1 | Uncharacterized protein. (2261 aa) | ||||
FABP1 | Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (151 aa) | ||||
MTTP | Microsomal triglyceride transfer protein large subunit; Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B. (894 aa) | ||||
SCARB1 | Scavenger receptor class B member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB- containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. (509 aa) | ||||
PLA2G3 | Phospholipase A2 group III. (501 aa) | ||||
PLA2G12B | Phospholipase A2 group XIIB. (194 aa) | ||||
PNLIP | Pancreatic triacylglycerol lipase. (464 aa) | ||||
PNLIPRP1 | Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa) | ||||
CD36 | Platelet glycoprotein 4 isoform X1; Belongs to the CD36 family. (472 aa) | ||||
NPC1L1 | NPC1-like intracellular cholesterol transporter 1 isoform 2. (1332 aa) | ||||
PLPP1 | Phospholipid phosphatase 1; Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1- phosphate/C1P. Also acts on N- oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound (By similarity). Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these [...] (290 aa) | ||||
LOC100624333 | Uncharacterized protein. (361 aa) | ||||
ACAT1 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa) | ||||
CEL | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (585 aa) | ||||
AGPAT1 | PlsC domain-containing protein. (364 aa) | ||||
PLA2G2F | Phospholipase A(2). (302 aa) | ||||
ABCG5 | ATP binding cassette subfamily G member 5. (657 aa) | ||||
APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (279 aa) | ||||
PLA2G5 | Phospholipase A(2). (138 aa) | ||||
PLA2G2D | Phospholipase A(2). (161 aa) | ||||
FABP2 | Fatty acid-binding protein, intestinal; FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity). (132 aa) | ||||
ACAT2 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (447 aa) | ||||
PLA2G10 | Phospholipase A(2). (188 aa) | ||||
PLA2G2E | Phospholipase A(2). (142 aa) | ||||
SLC27A1 | Solute carrier family 27 (Fatty acid transporter), member 1. (646 aa) | ||||
PNLIPRP2 | Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (574 aa) | ||||
DGAT2 | Uncharacterized protein. (339 aa) | ||||
GOT2 | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). (442 aa) | ||||
APOA4 | Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. (392 aa) | ||||
ABCG8 | ATP binding cassette subfamily G member 8. (730 aa) | ||||
PLPP2 | Phospholipid phosphatase 2. (368 aa) | ||||
AGPAT2 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (291 aa) | ||||
SLC27A4 | Solute carrier family 27 member 4. (673 aa) | ||||
PLPP3 | acidPPc domain-containing protein. (369 aa) | ||||
PLA2G1B | Phospholipase A2, major isoenzyme; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Belongs to the phospholipase A2 family. (146 aa) | ||||
DGAT1 | Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (665 aa) |