STRINGSTRING
NDUFA6 NDUFA6 POLR2F POLR2F KIF5A KIF5A GPX6 GPX6 GPX5 GPX5 KLC4 KLC4 PSMB5 PSMB5 GPX2 GPX2 PSMC1 PSMC1 NDUFB1 NDUFB1 LOC100157935 LOC100157935 RCOR1 RCOR1 KLC1 KLC1 BAX BAX AP2A1 AP2A1 NDUFA3 NDUFA3 MTOR MTOR CASP9 CASP9 NDUFS5 NDUFS5 PSMA8 PSMA8 TAF4B TAF4B PIK3C3 PIK3C3 LOC100524873 LOC100524873 HDAC2 HDAC2 COX7A2 COX7A2 ATG14 ATG14 NDUFA8 NDUFA8 PSMB7 PSMB7 TRAF2 TRAF2 NDUFB8 NDUFB8 NDUFS2 NDUFS2 CREB3L4 CREB3L4 PSMD4 PSMD4 PSMA5 PSMA5 VDAC3 VDAC3 TUBB1 TUBB1 UQCRC2 UQCRC2 CREBBP CREBBP COX5B COX5B HTT HTT SLC25A31 SLC25A31 DNAH10 DNAH10 VDAC2 VDAC2 PPIF PPIF MAPK8 MAPK8 BECN2 BECN2 DCTN3 DCTN3 KIF5B KIF5B LOC100127131 LOC100127131 PSMD6 PSMD6 PPARG PPARG NDUFB5 NDUFB5 IFT57 IFT57 ATP5PO ATP5PO SLC25A5 SLC25A5 NDUFV1 NDUFV1 PLCB3 PLCB3 COX8A COX8A ATG13 ATG13 SLC1A2 SLC1A2 LOC100524239 LOC100524239 CREB3L3 CREB3L3 TUBB4A TUBB4A NDUFB7 NDUFB7 NDUFA13 NDUFA13 UQCRQ UQCRQ SDHD SDHD SEM1 SEM1 PSMC2 PSMC2 NDUFB3 NDUFB3 PSMD1 PSMD1 NDUFA10 NDUFA10 CREB3L2 CREB3L2 CREB5 CREB5 CYCS CYCS NDUFS6 NDUFS6 HAP1 HAP1 PSMD3 PSMD3 PSMD11 PSMD11 DNAH9 DNAH9 ND1 ND1 ND2 ND2 COX1 COX1 COX2 COX2 ATP8 ATP8 ATP6 ATP6 COX3 COX3 ND3 ND3 ND4L ND4L ND4 ND4 ND5 ND5 ND6 ND6 CYTB CYTB AP2B1 AP2B1 COX5A COX5A GRIA4 GRIA4 ATG2A ATG2A EP300 EP300 POLR2C POLR2C HDAC1 HDAC1 UQCRFS1 UQCRFS1 RB1CC1 RB1CC1 NDUFA11 NDUFA11 POLR2B POLR2B ACTR10 ACTR10 NDUFA4 NDUFA4 POLR2A POLR2A DCTN4 DCTN4 DNAI2 DNAI2 ATP5MC2 ATP5MC2 POLR2K POLR2K DNAH1 DNAH1 LOC100519295 LOC100519295 DNAH12 DNAH12 ECE2 ECE2 CASP8 CASP8 TBPL1 TBPL1 SDHA SDHA POLR2E POLR2E TAF4 TAF4 UQCR10 UQCR10 MAP3K10 MAP3K10 KIF5C KIF5C GRM5 GRM5 ATP5F1B ATP5F1B MAPK10 MAPK10 GRIA3 GRIA3 NDUFA1 NDUFA1 ATP5F1E ATP5F1E NDUFB9 NDUFB9 SLC25A4 SLC25A4 SLC1A3 SLC1A3 CREB3 CREB3 DCTN5 DCTN5 GRIN2B GRIN2B PPARGC1A PPARGC1A PSMD9 PSMD9 PSMB3 PSMB3 NDUFS3 NDUFS3 DNAI1 DNAI1 DNAH5 DNAH5 MAP3K5 MAP3K5 GRIA1 GRIA1 AP2M1 AP2M1 GNAQ GNAQ CREB1 CREB1 PSMD12 PSMD12 ATP5PB ATP5PB SP1 SP1 GPX7 GPX7 PLCB4 PLCB4 COX4I2 COX4I2 DCTN6 DCTN6 CLTA CLTA COX6B COX6B TBP TBP SIN3A SIN3A NDUFAB1 NDUFAB1 POLR2D POLR2D APAF1 APAF1 COX6A2 COX6A2 PSMD7 PSMD7 TFAM TFAM POLR2I POLR2I DNAH17 DNAH17 GPX1 GPX1 DNAH7 DNAH7 ATP5F1C ATP5F1C ATG101 ATG101 GPX3 GPX3 GRIA2 GRIA2 NDUFS4 NDUFS4 NRF1 NRF1 COX6B2 COX6B2 CACNA1B CACNA1B COX7A1 COX7A1 BDNF BDNF VDAC1 VDAC1 ATP5MC3 ATP5MC3 COX7C COX7C SLC25A6 SLC25A6 NDUFV3 NDUFV3 TUBB2B TUBB2B CASP3 CASP3 PSMB4 PSMB4 CYC1 CYC1 ATP5PD ATP5PD GRIN1 GRIN1 NRBF2 NRBF2 TP53 TP53 DNAH14 DNAH14 ATP5PF ATP5PF PSMC4 PSMC4 PSMD8 PSMD8 TUBA8 TUBA8 DNAL1 DNAL1 TUBB6 TUBB6 TUBA1A TUBA1A KCNJ10 KCNJ10 DCTN1 DCTN1 ADRM1 ADRM1 DNALI1 DNALI1 PSMC6 PSMC6 NDUFV2 NDUFV2 ATG2B ATG2B COX6A1 COX6A1 WIPI2 WIPI2 PIK3R4 PIK3R4 COX7B COX7B NDUFS8 NDUFS8 PSMD14 PSMD14 PSMB1 PSMB1 NDUFB4 NDUFB4 ATP5F1A ATP5F1A PSMA7 PSMA7 PLCB2 PLCB2 NDUFA12 NDUFA12 PSMA1 PSMA1 DNAH3-2 DNAH3-2 ATP5MC1 ATP5MC1 PSMA2 PSMA2 DNAH11 DNAH11 ITPR1 ITPR1 POLR2J POLR2J TGM2 TGM2 PSMA4 PSMA4 CLTC CLTC PSMB2 PSMB2 PLCB1 PLCB1 PSMD13 PSMD13 ACTR1B ACTR1B PSMC3 PSMC3 WIPI1 WIPI1 LOC100155138 LOC100155138 NDUFA2 NDUFA2 NDUFB2 NDUFB2 AP2S1 AP2S1 NDUFC2 NDUFC2 PSMB6 PSMB6 KLC3 KLC3 POLR2G POLR2G POLR2H POLR2H DNAH6 DNAH6 AP2A2 AP2A2 BBC3 BBC3 NDUFB11 NDUFB11 SDHB SDHB NDUFS1 NDUFS1 TUBA4A TUBA4A DLG4 DLG4 DCTN2 DCTN2 REST REST SDHC SDHC CREB3L1 CREB3L1 DNAH8 DNAH8 TUBAL3 TUBAL3 DNAH2 DNAH2 ATP5F1D ATP5F1D NDUFA5 NDUFA5 NDUFB6 NDUFB6
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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NDUFA6NADH:ubiquinone oxidoreductase subunit A6; Belongs to the complex I LYR family. (154 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1085 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (220 aa)
GPX5Epididymal secretory glutathione peroxidase; May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. (219 aa)
KLC4Kinesin light chain 4 isoform X1. (616 aa)
PSMB5Uncharacterized protein. (84 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
PSMC126S proteasome regulatory subunit 4 isoform a; Belongs to the AAA ATPase family. (440 aa)
NDUFB1Uncharacterized protein. (58 aa)
LOC100157935Uncharacterized protein. (70 aa)
RCOR1REST corepressor 1. (487 aa)
KLC1Uncharacterized protein. (677 aa)
BAXTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (480 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
NDUFA3Uncharacterized protein. (169 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (438 aa)
NDUFS5Uncharacterized protein. (106 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
TAF4BTATA-box binding protein associated factor 4b. (869 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Requ [...] (863 aa)
LOC100524873Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
COX7A2Uncharacterized protein. (115 aa)
ATG14Autophagy related 14. (510 aa)
NDUFA8CHCH domain-containing protein. (249 aa)
PSMB7Proteasome subunit beta type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...] (277 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (520 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
NDUFS2NADH dehydrogenase ubiquinone iron-sulfur protein 2, mitochondrial isoform 1; Belongs to the complex I 49 kDa subunit family. (473 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (395 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
PSMA5Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (232 aa)
VDAC3Voltage-dependent anion-selective channel protein 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules; Belongs to the eukaryotic mitochondrial porin family. (284 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
UQCRC2Cytochrome b-c1 complex subunit 2, mitochondrial; Belongs to the peptidase M16 family. (453 aa)
CREBBPCREB-binding protein isoform a. (2440 aa)
COX5BCytochrome c oxidase subunit 5B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (129 aa)
HTTHuntingtin. (3138 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
DNAH10Dynein axonemal heavy chain 10. (4592 aa)
VDAC2Voltage-dependent anion-selective channel protein 2; Forms a channel through the cell membrane that allows diffusion from small hydrophilic molecules. (294 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (237 aa)
MAPK8Mitogen-activated protein kinase. (411 aa)
BECN2Beclin 2. (444 aa)
DCTN3Dynactin subunit 3 isoform 1. (186 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
LOC100127131Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (474 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (450 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (528 aa)
NDUFB5NADH dehydrogenase ubiquinone 1 beta subcomplex subunit 5, mitochondrial isoform 1. (189 aa)
IFT57Intraflagellar transport 57. (428 aa)
ATP5POATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (213 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
COX8ACytochrome c oxidase subunit 8A, mitochondrial. (69 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
SLC1A2Amino acid transporter. (639 aa)
LOC100524239Cytochrome b-c1 complex subunit 10. (56 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (493 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Belongs to the tubulin family. (443 aa)
NDUFB7NADH dehydrogenase ubiquinone 1 beta subcomplex subunit 7. (137 aa)
NDUFA13Uncharacterized protein. (144 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (177 aa)
SEM1Uncharacterized protein. (57 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (114 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (357 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
CREB5cAMP responsive element binding protein 5. (510 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (123 aa)
HAP1Huntingtin associated protein 1. (637 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (421 aa)
DNAH9Dynein axonemal heavy chain 9. (4487 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (347 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (229 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (67 aa)
ATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (115 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (459 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (606 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (175 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
AP2B1AP complex subunit beta. (957 aa)
COX5ACytochrome c oxidase subunit 5A, mitochondrial. (152 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (884 aa)
ATG2AAutophagy related 2A. (1929 aa)
EP300E1A binding protein p300. (2420 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3. (275 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
UQCRFS1Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1. (295 aa)
RB1CC1RB1 inducible coiled-coil 1. (1608 aa)
NDUFA11NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 11 isoform 1. (141 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1251 aa)
ACTR10Actin-related protein 10; Belongs to the actin family. (417 aa)
NDUFA4Cytochrome c oxidase subunit NDUFA4. (137 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1942 aa)
DCTN4Dynactin subunit 4. (501 aa)
DNAI2Dynein intermediate chain 2, axonemal isoform X2. (607 aa)
ATP5MC2ATP synthase F(0) complex subunit C2, mitochondrial isoform X1. (225 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
DNAH1Dynein axonemal heavy chain 1. (4266 aa)
LOC100519295Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
DNAH12Uncharacterized protein. (3945 aa)
ECE2Uncharacterized protein. (1628 aa)
CASP8Caspase-8 isoform X2; Belongs to the peptidase C14A family. (486 aa)
TBPL1TATA-box binding protein like 1. (206 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (Probable). Can act as a tumor suppressor (By similarity); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (664 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
TAF4TATA-box binding protein associated factor 4. (1031 aa)
UQCR10Ubiquinol-cytochrome c reductase complex. (64 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (951 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (956 aa)
GRM5Glutamate metabotropic receptor 5. (1212 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (570 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (70 aa)
ATP5F1EUncharacterized protein. (136 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (221 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
SLC1A3Amino acid transporter. (498 aa)
CREB3cAMP responsive element binding protein 3. (373 aa)
DCTN5Dynactin subunit 5. (182 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] (796 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PSMB3Proteasome subunit beta. (205 aa)
NDUFS3NADH dehydrogenase ubiquinone iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (264 aa)
DNAI1Dynein axonemal intermediate chain 1. (704 aa)
DNAH5Dynein axonemal heavy chain 5. (4586 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1425 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (435 aa)
GNAQGuanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. (359 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12 isoform 1. (456 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
SP1Transcription factor Sp1 isoform a. (786 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (317 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (171 aa)
DCTN6Dynactin 6. (190 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
COX6BCytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
TBPUncharacterized protein. (153 aa)
SIN3ASIN3 transcription regulator family member A. (1274 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
POLR2DRNA polymerase II subunit D. (184 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
TFAMTranscription factor A, mitochondrial; Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymeras [...] (246 aa)
POLR2IDNA-directed RNA polymerase II subunit RPB9; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity). (125 aa)
DNAH17Dynein axonemal heavy chain 17. (4459 aa)
GPX1Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. (205 aa)
DNAH7Dynein axonemal heavy chain 7. (4022 aa)
ATP5F1CATP synthase subunit gamma. (297 aa)
ATG101Autophagy-related protein 101 isoform X1. (218 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
NRF1Nuclear respiratory factor 1 isoform 1. (503 aa)
COX6B2Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (88 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2329 aa)
COX7A1Cytochrome c oxidase subunit 7A1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembran [...] (80 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (260 aa)
VDAC1Voltage-dependent anion-selective channel protein 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition p [...] (302 aa)
ATP5MC3ATP-synt_C domain-containing protein. (312 aa)
COX7CCytochrome c oxidase subunit 7C, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (63 aa)
SLC25A6ADP/ATP translocase 3, N-terminally processed; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (By similarity). (355 aa)
NDUFV3Uncharacterized protein. (456 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. (465 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). (266 aa)
PSMB4Proteasome subunit beta type-4; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...] (264 aa)
CYC1Cytochrome c1, heme protein, mitochondrial. (326 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (170 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
NRBF2Nuclear receptor binding factor 2. (288 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (442 aa)
DNAH14Uncharacterized protein. (592 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of t [...] (116 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (497 aa)
DNAL1Dynein axonemal light chain 1. (151 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (411 aa)
TUBA1ADetyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
DCTN1CAP-Gly domain-containing protein. (1281 aa)
ADRM1Adhesion regulating molecule 1. (423 aa)
DNALI1Dynein axonemal light intermediate chain 1. (317 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (481 aa)
NDUFV2NADH dehydrogenase ubiquinone flavoprotein 2, mitochondrial. (249 aa)
ATG2BAutophagy related 2B. (2077 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (559 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1302 aa)
COX7BCytochrome c oxidase subunit 7B, mitochondrial. (80 aa)
NDUFS8NADH dehydrogenase ubiquinone iron-sulfur protein 8, mitochondrial. (239 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
PSMB1Proteasome subunit beta. (241 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (129 aa)
ATP5F1AATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (737 aa)
PSMA7Proteasome subunit alpha type. (267 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (185 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
DNAH3-2Uncharacterized protein. (668 aa)
ATP5MC1ATP synthase F(0) complex subunit C1, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanis [...] (136 aa)
PSMA2Proteasome endopeptidase complex. (243 aa)
DNAH11Dynein axonemal heavy chain 11. (4525 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2759 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (164 aa)
TGM2Transglutaminase 2. (696 aa)
PSMA4Proteasome subunit alpha type. (281 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1702 aa)
PSMB2Proteasome subunit beta. (201 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (419 aa)
ACTR1BActin related protein 1B; Belongs to the actin family. (375 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (629 aa)
WIPI1Uncharacterized protein. (477 aa)
LOC100155138Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (465 aa)
NDUFA2NADH:ubiquinone oxidoreductase subunit A2. (105 aa)
NDUFB2Uncharacterized protein. (119 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (122 aa)
PSMB6Uncharacterized protein. (334 aa)
KLC3Kinesin light chain 3. (549 aa)
POLR2GRNA polymerase II subunit G. (231 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (153 aa)
DNAH6Dynein axonemal heavy chain 6. (4155 aa)
AP2A2Adaptor related protein complex 2 subunit alpha 2. (1108 aa)
BBC3Uncharacterized protein. (361 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (176 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (328 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (749 aa)
TUBA4ATubulin alpha 4a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (618 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (764 aa)
DCTN2Dynactin subunit 2. (408 aa)
RESTRE1 silencing transcription factor. (1108 aa)
SDHCSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the cytochrome b560 family. (176 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
DNAH8DHC_N1 domain-containing protein. (592 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
DNAH2AAA_6 domain-containing protein. (202 aa)
ATP5F1DATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (179 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (117 aa)
NDUFB6NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (188 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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