STRINGSTRING
LOC100152135 LOC100152135 LOC100152878 LOC100152878 CDKN1A CDKN1A SRF SRF NFKBIA NFKBIA GTF2A1 GTF2A1 PSMC1 PSMC1 VAC14 VAC14 CCNE1 CCNE1 BAX BAX UBR4 UBR4 CDC20 CDC20 HDAC2 HDAC2 CDKN2B CDKN2B TRAF1 TRAF1 TRAF2 TRAF2 YWHAZ YWHAZ CCNE2 CCNE2 ATP6V0D2 ATP6V0D2 LYN LYN CREB3L4 CREB3L4 VDAC3 VDAC3 USP7 USP7 CREBBP CREBBP REL REL CCNA1 CCNA1 RB1 RB1 YWHAH YWHAH RANBP1 RANBP1 EGR2 EGR2 NFKB2 NFKB2 DDX3X DDX3X IRF7 IRF7 RELA RELA DDB1 DDB1 CREB3L3 CREB3L3 C3 C3 CHEK1 CHEK1 GTF2E2 GTF2E2 CREB3L2 CREB3L2 CREB5 CREB5 SKP2 SKP2 LOC100519930 LOC100519930 GRB2 GRB2 HDAC5 HDAC5 STAT3 STAT3 STAT5A STAT5A STAT5B STAT5B KAT2A KAT2A SNW1 SNW1 EP300 EP300 HDAC1 HDAC1 LOC100624590 LOC100624590 CDK4 CDK4 HIST1H2BD HIST1H2BD CCR8 CCR8 HDAC10 HDAC10 MRPS18B MRPS18B HNRNPK HNRNPK CASP8 CASP8 TBPL1 TBPL1 KAT2B KAT2B HDAC11 HDAC11 PMAIP1 PMAIP1 LOC100621389 LOC100621389 TRAF5 TRAF5 CDC42 CDC42 SRC SRC IL6ST IL6ST JAK3 JAK3 ATF6B ATF6B DLG1 DLG1 CREB3 CREB3 JAK1 JAK1 BAK1 BAK1 RBL2 RBL2 POLB POLB SYK SYK CCR4 CCR4 PRKACA PRKACA CREB1 CREB1 RBPJ RBPJ MAD1L1 MAD1L1 ACTN4 ACTN4 GTF2H2 GTF2H2 TBP TBP UBE3A UBE3A CHD4 CHD4 RBL1 RBL1 SCIN SCIN BAD BAD TRAF3 TRAF3 CDK1 CDK1 CDKN1B CDKN1B RHOA RHOA NRAS NRAS H2BE1 H2BE1 NFKB1 NFKB1 GTF2A1L GTF2A1L IKBKG IKBKG H2BU1 H2BU1 CASP3 CASP3 TP53 TP53 HRAS HRAS PKM PKM ATF2 ATF2 PIK3CB PIK3CB PIK3CA PIK3CA LOC100511937 LOC100511937 CCND2 CCND2 EGR3 EGR3 LOC100517129 LOC100517129 MDM2 MDM2 H2BC21 H2BC21 EIF2AK2 EIF2AK2 MAPK3 MAPK3 RBPJL RBPJL TRADD TRADD YWHAB YWHAB HDAC6 HDAC6 PRKACB PRKACB YWHAG YWHAG CCND1 CCND1 LTBR LTBR IRF9 IRF9 HDAC8 HDAC8 PXN PXN YWHAQ YWHAQ SND1 SND1 HDAC9 HDAC9 RASA2 RASA2 GTF2A2 GTF2A2 CCR5 CCR5 CREB3L1 CREB3L1 MAPK1 MAPK1 HDAC4 HDAC4 HDAC7 HDAC7
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC100152135Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC100152878Histone H2B; Belongs to the histone H2B family. (127 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (163 aa)
SRFSerum response factor. (512 aa)
NFKBIANF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. (314 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
PSMC126S proteasome regulatory subunit 4 isoform a; Belongs to the AAA ATPase family. (440 aa)
VAC14Protein VAC14 homolog isoform 1. (783 aa)
CCNE1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (410 aa)
BAXTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (480 aa)
UBR4Ubiquitin protein ligase E3 component n-recognin 4. (5180 aa)
CDC20Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] (499 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (131 aa)
TRAF1TNF receptor-associated factor. (415 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (520 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (260 aa)
CCNE2G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
LYNTyrosine-protein kinase. (512 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (395 aa)
VDAC3Voltage-dependent anion-selective channel protein 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules; Belongs to the eukaryotic mitochondrial porin family. (284 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1109 aa)
CREBBPCREB-binding protein isoform a. (2440 aa)
RELREL proto-oncogene, NF-kB subunit. (586 aa)
CCNA1Cyclin-A1 isoform X1; Belongs to the cyclin family. (421 aa)
RB1RB transcriptional corepressor 1. (938 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
RANBP1RAN binding protein 1. (206 aa)
EGR2E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity); Belongs to the EGR C2H2-type zinc-finger protein family. (471 aa)
NFKB2Nuclear factor NF-kappa-B p100 subunit isoform X1. (901 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa)
IRF7Interferon regulatory factor 7. (481 aa)
RELATranscription factor p65 isoform 1. (573 aa)
DDB1Damage specific DNA binding protein 1. (1139 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (493 aa)
C3Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (By similarity). [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. (1661 aa)
CHEK1Serine/threonine-protein kinase Chk1 isoform X2; Belongs to the protein kinase superfamily. (476 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (290 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
CREB5cAMP responsive element binding protein 5. (510 aa)
SKP2S-phase kinase-associated protein 2 isoform 1. (436 aa)
LOC100519930Histone domain-containing protein; Belongs to the histone H2B family. (122 aa)
GRB2Growth factor receptor-bound protein 2 isoform 1. (217 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1131 aa)
STAT3Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa)
STAT5ASignal transducer and activator of transcription 5A; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation (By similarity). (799 aa)
STAT5BSignal transducer and activator of transcription 5B; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation. (787 aa)
KAT2ALysine acetyltransferase 2A. (857 aa)
SNW1SNW domain-containing protein 1 isoform 2. (536 aa)
EP300E1A binding protein p300. (2420 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
LOC100624590ATP-dependent RNA helicase DDX3X isoform 2; Belongs to the DEAD box helicase family. (670 aa)
CDK4Cyclin-dependent kinase 4; Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. [...] (303 aa)
HIST1H2BDHistone H2B; Belongs to the histone H2B family. (126 aa)
CCR8C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (379 aa)
HDAC10Histone deacetylase 10. (671 aa)
MRPS18B28S ribosomal protein S18b, mitochondrial; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily. (258 aa)
HNRNPKUncharacterized protein. (464 aa)
CASP8Caspase-8 isoform X2; Belongs to the peptidase C14A family. (486 aa)
TBPL1TATA-box binding protein like 1. (206 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (831 aa)
HDAC11Histone deacetylase 11 isoform 1. (347 aa)
PMAIP1Uncharacterized protein. (121 aa)
LOC100621389Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
SRCTyrosine-protein kinase. (559 aa)
IL6STInterleukin 6 signal transducer. (938 aa)
JAK3Tyrosine-protein kinase. (1103 aa)
ATF6BActivating transcription factor 6 beta. (717 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
CREB3cAMP responsive element binding protein 3. (373 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
BAK1Uncharacterized protein. (266 aa)
RBL2RB transcriptional corepressor like 2. (1140 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (334 aa)
SYK40 kDa tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the recepto [...] (628 aa)
CCR4C-C chemokine receptor type 4 isoform X1; Belongs to the G-protein coupled receptor 1 family. (360 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...] (357 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (491 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (737 aa)
ACTN4Actinin alpha 4. (1160 aa)
GTF2H2VWFA domain-containing protein. (613 aa)
TBPUncharacterized protein. (153 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (876 aa)
CHD4Uncharacterized protein. (1863 aa)
RBL1RB transcriptional corepressor like 1. (1044 aa)
SCINAdseverin; Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Severing activity is inhibited by phosphatidylinositol 4,5-bis- phosphate (PIP2) (By similarity). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (By similarity). Plays a role in osteoclastogenesis (OCG) and actin cytoskel [...] (715 aa)
BADBCL2 associated agonist of cell death. (209 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
CDK1Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily. (297 aa)
CDKN1Bp27Kip1. (198 aa)
RHOATransforming protein RhoA isoform 1. (193 aa)
NRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
NFKB1Uncharacterized protein. (898 aa)
GTF2A1LGeneral transcription factor IIA subunit 1 like. (478 aa)
IKBKGNF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activati [...] (451 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). (266 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (442 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PKMMultifunctional fusion protein; Belongs to the pyruvate kinase family. (1202 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC100511937Uncharacterized protein. (532 aa)
CCND2G1/S-specific cyclin-D2; Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...] (288 aa)
EGR3Early growth response protein 3 isoform 1. (387 aa)
LOC100517129Uncharacterized protein. (680 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (496 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (546 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (516 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (304 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (264 aa)
HDAC6Histone deacetylase 6. (1159 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subu [...] (394 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
LTBRUncharacterized protein. (432 aa)
IRF9IRF tryptophan pentad repeat domain-containing protein. (418 aa)
HDAC8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (441 aa)
PXNUncharacterized protein. (1072 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (246 aa)
SND1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (910 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1137 aa)
RASA2RAS p21 protein activator 2. (854 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (361 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (568 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1160 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (980 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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