(51 nodes) Regulation of calcium-mediated signaling network (Camelus dromedarius)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	PRNP	Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (255 aa)
	HOMER3	Homer protein-like protein 3. (359 aa)
	ADA	Adenosine deaminase. (363 aa)
	MYH7B	Myosin-7B. (1984 aa)
	MYOZ1	Myozenin-1. (300 aa)
	ACTN3	Alpha-actinin-3. (944 aa)
	HOMER2	Homer protein-like protein 2. (354 aa)
	C10orf71	Cardiac-enriched FHL2-interacting protein. (1428 aa)
	P2RX4	P2X purinoceptor 4. (448 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (231 aa)
	MTOR	Serine/threonine-protein kinase mTOR. (2546 aa)
	SLA2	Src-like-adapter 2. (262 aa)
	MAPK7	Mitogen-activated protein kinase 7. (763 aa)
	CMYA5	Cardiomyopathy-associated protein 5. (4067 aa)
	SPPL3	Signal peptide peptidase-like 3. (384 aa)
	PTK2B	Protein-tyrosine kinase 2-beta. (1008 aa)
	GPR143	G protein-coupled receptor 143. (440 aa)
	TNF	Tumor necrosis factor. (233 aa)
	BST1	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2. (320 aa)
	CMKLR1	Chemokine-like receptor 1. (365 aa)
	CHERP	Calcium homeostasis endoplasmic reticulum protein. (947 aa)
	ATP2B4	Plasma membrane calcium-transporting ATPase 4. (1214 aa)
	TMEM100	Transmembrane protein 100. (134 aa)
	Cadr_000012111	Sialic acid-binding Ig-like lectin 10. (737 aa)
	TRAT1	T-cell receptor-associated transmembrane adapter 1. (187 aa)
	SLC24A4	Sodium/potassium/calcium exchanger 4. (622 aa)
	PLCG2	1-phosphatidylinositol 4. (1265 aa)
	SLC8A2	Sodium/calcium exchanger 2. (922 aa)
	CDH13	Cadherin-13. (713 aa)
	EFHB	EF-hand domain-containing family member B isoform X1. (830 aa)
	RCAN1	Calcipressin-1. (197 aa)
	HTT	Huntingtin. (3088 aa)
	FHL2	Four and a half LIM domains protein 2. (279 aa)
	MYOZ2	Myozenin-2. (267 aa)
	CHP2	Calcineurin B homologous protein 2. (196 aa)
	NEUROD2	Neurogenic differentiation factor 2. (382 aa)
	LRRK2	Leucine-rich repeat serine/threonine-protein kinase 2. (2558 aa)
	ERBB3	Receptor tyrosine-protein kinase erbB-3 isoform X1. (1338 aa)
	SLC9A1	Sodium/hydrogen exchanger 1. (814 aa)
	ITPR1	Inositol 1. (2759 aa)
	LMCD1	LIM and cysteine-rich domains protein 1. (363 aa)
	CIB1	Calcium and integrin-binding protein 1. (191 aa)
	IGF1	Insulin-like growth factor I. (194 aa)
	GSK3B	Glycogen synthase kinase-3 beta isoform X1. (433 aa)
	LOC105097864	C-C motif chemokine 3. (92 aa)
	JPT2	Jupiter microtubule associated-like protein 2. (188 aa)
	TBC1D10C	Carabin. (446 aa)
	PDK2	[Pyruvate dehydrogenase ] kinase isozyme 2. (407 aa)
	TMBIM4	Protein lifeguard 4. (238 aa)
	LOC105093287	Store-operated calcium entry regulator STIMATE. (294 aa)
	DYRK2	Dual specificity tyrosine-phosphorylation-regulated kinase 2. (599 aa)

Your Current Organism:

Camelus dromedarius

NCBI taxonomy Id: 9838
Other names: Arabian camel, C. dromedarius, camel, dromedaries, dromedary, dromedary camel, one-humped camel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN3	MYH7B	ENSCDRP00005022104	ENSCDRP00005020869	Alpha-actinin-3.	Myosin-7B.	0.404
ACTN3	MYOZ1	ENSCDRP00005022104	ENSCDRP00005021364	Alpha-actinin-3.	Myozenin-1.	0.875
ACTN3	MYOZ2	ENSCDRP00005022104	ENSCDRP00005005784	Alpha-actinin-3.	Myozenin-2.	0.551
CHP2	SLC9A1	ENSCDRP00005006239	ENSCDRP00005010067	Calcineurin B homologous protein 2.	Sodium/hydrogen exchanger 1.	0.663
CIB1	SLC9A1	ENSCDRP00005013502	ENSCDRP00005010067	Calcium and integrin-binding protein 1.	Sodium/hydrogen exchanger 1.	0.411
CMYA5	MYOZ2	ENSCDRP00005027230	ENSCDRP00005005784	Cardiomyopathy-associated protein 5.	Myozenin-2.	0.538
ERBB3	IGF1	ENSCDRP00005007491	ENSCDRP00005014415	Receptor tyrosine-protein kinase erbB-3 isoform X1.	Insulin-like growth factor I.	0.729
ERBB3	PLCG2	ENSCDRP00005007491	ENSCDRP00005001396	Receptor tyrosine-protein kinase erbB-3 isoform X1.	1-phosphatidylinositol 4.	0.958
ERBB3	PTK2B	ENSCDRP00005007491	ENSCDRP00005028080	Receptor tyrosine-protein kinase erbB-3 isoform X1.	Protein-tyrosine kinase 2-beta.	0.512
GSK3B	IGF1	ENSCDRP00005015134	ENSCDRP00005014415	Glycogen synthase kinase-3 beta isoform X1.	Insulin-like growth factor I.	0.593
GSK3B	MTOR	ENSCDRP00005015134	ENSCDRP00005023956	Glycogen synthase kinase-3 beta isoform X1.	Serine/threonine-protein kinase mTOR.	0.403
GSK3B	PRNP	ENSCDRP00005015134	ENSCDRP00005012935	Glycogen synthase kinase-3 beta isoform X1.	Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...]	0.918
GSK3B	RCAN1	ENSCDRP00005015134	ENSCDRP00005004098	Glycogen synthase kinase-3 beta isoform X1.	Calcipressin-1.	0.433
HOMER2	HOMER3	ENSCDRP00005023065	ENSCDRP00005019103	Homer protein-like protein 2.	Homer protein-like protein 3.	0.923
HOMER3	HOMER2	ENSCDRP00005019103	ENSCDRP00005023065	Homer protein-like protein 3.	Homer protein-like protein 2.	0.923
HOMER3	ITPR1	ENSCDRP00005019103	ENSCDRP00005010261	Homer protein-like protein 3.	Inositol 1.	0.635
HTT	ITPR1	ENSCDRP00005004925	ENSCDRP00005010261	Huntingtin.	Inositol 1.	0.952
HTT	PRNP	ENSCDRP00005004925	ENSCDRP00005012935	Huntingtin.	Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...]	0.599
IGF1	ERBB3	ENSCDRP00005014415	ENSCDRP00005007491	Insulin-like growth factor I.	Receptor tyrosine-protein kinase erbB-3 isoform X1.	0.729
IGF1	GSK3B	ENSCDRP00005014415	ENSCDRP00005015134	Insulin-like growth factor I.	Glycogen synthase kinase-3 beta isoform X1.	0.593