(99 nodes) Synaptic vesicle cycle network (Camelus dromedarius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYNJ1	Synaptojanin-1. (1611 aa)
	RIMS1	Regulating synaptic membrane exocytosis protein 1. (1012 aa)
	RAP1A	Ras-related protein Rap-1A. (183 aa)
	SH3GL2	Endophilin-A1. (317 aa)
	AP3B1	AP-3 complex subunit beta-1. (1089 aa)
	NLGN1	Neuroligin-1. (823 aa)
	STX3	Syntaxin-3. (289 aa)
	SNCG	Synuclein gamma. (116 aa)
	STX4	Syntaxin-4. (320 aa)
	LRRC1	Leucine-rich repeat-containing protein 1. (573 aa)
	SYT9	Synaptotagmin-9. (501 aa)
	STXBP1	Syntaxin-binding protein 1. (603 aa)
	UNC13A	Protein unc-13-like protein A. (1723 aa)
	Cadr_000018633	Vesicle-associated membrane protein 2. (162 aa)
	OPHN1	Oligophrenin-1. (802 aa)
	RIMS3	Regulating synaptic membrane exocytosis protein 3. (308 aa)
	SYT1	Synaptotagmin-1. (422 aa)
	Cadr_000017046	Alpha-synuclein. (109 aa)
	SV2A	Synaptic vesicle glycoprotein 2A. (742 aa)
	P2RX7	P2X purinoceptor 7. (595 aa)
	SYN1	Synapsin-2. (706 aa)
	ERC2	ELKS/RAB6-interacting/CAST family member 2. (1066 aa)
	UNC13C	Protein unc-13-like protein C. (2217 aa)
	TBC1D24	TBC1 domain family member 24. (559 aa)
	SH3GL3	Endophilin-A3. (347 aa)
	SNAPIN	SNARE-associated protein Snapin. (136 aa)
	NLGN3	Neuroligin-3. (848 aa)
	SLC18A2	Synaptic vesicular amine transporter. (518 aa)
	SNAP23	Synaptosomal-associated protein 23. (211 aa)
	SLC17A8	Vesicular glutamate transporter 3. (589 aa)
	SYNJ2	Synaptojanin-2. (1475 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa)
	SYP	Synaptophysin. (312 aa)
	NLGN4X	Neuroligin-4. (816 aa)
	CPLX4	Complexin-3/4. (160 aa)
	SYNDIG1	Synapse differentiation-inducing gene protein 1. (295 aa)
	PCLO	Protein piccolo. (2627 aa)
	ENSCDRP00005028826	annotation not available (639 aa)
	SYT2	Synaptotagmin-2. (423 aa)
	CTNNB1	Catenin beta-1. (783 aa)
	CADPS	Calcium-dependent secretion activator 1. (1298 aa)
	SYNPR	Synaptoporin. (285 aa)
	SYT8	Synaptotagmin-8. (388 aa)
	RIMS2	Regulating synaptic membrane exocytosis protein 2. (1587 aa)
	STON1	Stonin-1. (728 aa)
	AMPH	Amphiphysin. (679 aa)
	DOC2B	Double C2-like domain-containing protein beta. (374 aa)
	Syntaxin-4	Syntaxin-4. (61 aa)
	CLCN3	H exchange transporter 3. (866 aa)
	GIT2	ARF GTPase-activating protein GIT2. (758 aa)
	OTOF	Otoferlin. (1997 aa)
	STX1B	Syntaxin-1B. (341 aa)
	DNM3	Dynamin-3 isoform X2. (869 aa)
	SNCB	Beta-synuclein. (134 aa)
	PRRT2	Proline-rich transmembrane protein 2 isoform X2. (348 aa)
	RAB3A	Ras-related protein Rab-3A. (302 aa)
	SNAP29	Synaptosomal-associated protein 29. (240 aa)
	ENSCDRP00005016077	annotation not available (180 aa)
	Cadr_000025108	AP-3 complex subunit delta-1. (279 aa)
	ENSCDRP00005015466	annotation not available (70 aa)
	SNCA	Alpha-synuclein. (140 aa)
	DNM1	Dynamin-1. (864 aa)
	GIT1	ARF GTPase-activating protein GIT1. (757 aa)
	DNM2	Dynamin-1. (895 aa)
	STX11	Syntaxin-11. (304 aa)
	NOSTRIN	Nostrin. (506 aa)
	SLC17A6	Vesicular glutamate transporter 2. (582 aa)
	SLC32A1	Vesicular inhibitory amino acid transporter. (526 aa)
	Cadr_000015837	Protein unc-13-like protein B. (4266 aa)
	SLC18A1	Chromaffin granule amine transporter. (512 aa)
	SNAP47	Synaptosomal-associated protein 47. (420 aa)
	STX2	Syntaxin-2. (260 aa)
	SCRIB	Protein scribble-like protein. (1691 aa)
	DENND1A	DENN domain-containing protein 1A. (1072 aa)
	SLC17A7	Vesicular glutamate transporter 1. (560 aa)
	PICALM	Phosphatidylinositol-binding clathrin assembly protein. (713 aa)
	CTBP2	Uncharacterized protein. (983 aa)
	SNAP25	Synaptosomal-associated protein 25. (206 aa)
	SYT5	Synaptotagmin-5. (386 aa)
	PSEN1	Presenilin-1. (468 aa)
	CANX	Calnexin. (593 aa)
	LRRK2	Leucine-rich repeat serine/threonine-protein kinase 2. (2558 aa)
	DNAJC6	Putative tyrosine-protein phosphatase auxilin. (973 aa)
	SNAP91	Clathrin coat assembly protein AP180. (869 aa)
	CPLX3	Complexin-3. (195 aa)
	Cadr_000018349	Actin. (626 aa)
	CADPS2	Calcium-dependent secretion activator 2 isoform X1. (1157 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (801 aa)
	PACSIN1	Protein kinase C and casein kinase substrate in neurons protein 1. (444 aa)
	SH3GL1	Endophilin-A2. (414 aa)
	CPLX2	Complexin-2. (134 aa)
	STX1A	Syntaxin-1A. (335 aa)
	PPFIA3	Liprin-alpha-3. (1194 aa)
	FCHO2	F-BAR domain only protein 2. (810 aa)
	STX19	Syntaxin 11. (294 aa)
	STON2	Stonin-2. (895 aa)
	BTBD8	AP2-interacting clathrin-endocytosis protein. (1784 aa)
	ITSN1	Intersectin-1. (1721 aa)
	RAB5A	Ras-related protein Rab-5A. (215 aa)

Your Current Organism:

Camelus dromedarius

NCBI taxonomy Id: 9838
Other names: Arabian camel, C. dromedarius, camel, dromedaries, dromedary, dromedary camel, one-humped camel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	BRAF	ENSCDRP00005026436	ENSCDRP00005005836	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	B-Raf proto-oncogene, serine/threonine kinase.	0.495
ACTB	CANX	ENSCDRP00005026436	ENSCDRP00005008002	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Calnexin.	0.576
ACTB	CTNNB1	ENSCDRP00005026436	ENSCDRP00005029436	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Catenin beta-1.	0.663
ACTB	ITSN1	ENSCDRP00005026436	ENSCDRP00005003909	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Intersectin-1.	0.480
ACTB	PSEN1	ENSCDRP00005026436	ENSCDRP00005008932	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Presenilin-1.	0.432
ACTB	SNAP25	ENSCDRP00005026436	ENSCDRP00005009329	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Synaptosomal-associated protein 25.	0.480
ACTB	SNCA	ENSCDRP00005026436	ENSCDRP00005015017	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Alpha-synuclein.	0.515
ACTB	SYP	ENSCDRP00005026436	ENSCDRP00005027341	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Synaptophysin.	0.591
AMPH	DNM1	ENSCDRP00005018508	ENSCDRP00005014169	Amphiphysin.	Dynamin-1.	0.870
AMPH	DNM2	ENSCDRP00005018508	ENSCDRP00005012634	Amphiphysin.	Dynamin-1.	0.949
AMPH	DNM3	ENSCDRP00005018508	ENSCDRP00005017690	Amphiphysin.	Dynamin-3 isoform X2.	0.442
AMPH	FCHO2	ENSCDRP00005018508	ENSCDRP00005004476	Amphiphysin.	F-BAR domain only protein 2.	0.746
AMPH	ITSN1	ENSCDRP00005018508	ENSCDRP00005003909	Amphiphysin.	Intersectin-1.	0.663
AMPH	PICALM	ENSCDRP00005018508	ENSCDRP00005009638	Amphiphysin.	Phosphatidylinositol-binding clathrin assembly protein.	0.425
AMPH	SH3GL1	ENSCDRP00005018508	ENSCDRP00005005743	Amphiphysin.	Endophilin-A2.	0.559
AMPH	SH3GL2	ENSCDRP00005018508	ENSCDRP00005000708	Amphiphysin.	Endophilin-A1.	0.609
AMPH	SH3GL3	ENSCDRP00005018508	ENSCDRP00005023913	Amphiphysin.	Endophilin-A3.	0.459
AMPH	STON2	ENSCDRP00005018508	ENSCDRP00005004269	Amphiphysin.	Stonin-2.	0.434
AMPH	SYNJ1	ENSCDRP00005018508	ENSCDRP00005002974	Amphiphysin.	Synaptojanin-1.	0.767
AMPH	SYNJ2	ENSCDRP00005018508	ENSCDRP00005025530	Amphiphysin.	Synaptojanin-2.	0.720