STRINGSTRING
PIK3CA PIK3CA EREG EREG AREG AREG AKT1 AKT1 SOS2 SOS2 LOC105095080 LOC105095080 FOS FOS POLK POLK TGFB3 TGFB3 MAP2K1 MAP2K1 BAX BAX TCF7 TCF7 MAP2K2 MAP2K2 NRAS NRAS PIK3R1 PIK3R1 MAPK9 MAPK9 MYC MYC RPS6KB1 RPS6KB1 RHOA RHOA MAPK10 MAPK10 APC APC GRB2 GRB2 GADD45A GADD45A HRAS HRAS PIK3CB PIK3CB RAC2 RAC2 RAC3 RAC3 GADD45B GADD45B EGF EGF SMAD4 SMAD4 MAPK3 MAPK3 TP53 TP53 AXIN1 AXIN1 AKT2 AKT2 TGFBR2 TGFBR2 TGFA TGFA GSK3B GSK3B RPS6KB2 RPS6KB2 CDKN1A CDKN1A PIK3R2 PIK3R2 PIK3CD PIK3CD RALB RALB SMAD2 SMAD2 LEF1 LEF1 RALA RALA AKT3 AKT3 SOS1 SOS1 MLH1 MLH1 MAPK8 MAPK8 TGFBR1 TGFBR1 CASP3 CASP3 EGFR EGFR ARAF ARAF TGFB1 TGFB1 MTOR MTOR TCF7L1 TCF7L1 TGFB2 TGFB2 GADD45G GADD45G APPL1 APPL1 RAF1 RAF1 BAD BAD MSH3 MSH3 PIK3R3 PIK3R3 PMAIP1 PMAIP1 CASP9 CASP9 KRAS KRAS CTNNB1 CTNNB1 AXIN2 AXIN2 BCL2L11 BCL2L11 BIRC5 BIRC5 TCF7L2 TCF7L2 DCC DCC BAK1 BAK1 MAPK1 MAPK1 MSH2 MSH2 MSH6 MSH6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CAPhosphatidylinositol 4. (1068 aa)
EREGProepiregulin. (166 aa)
AREGAmphiregulin. (253 aa)
AKT1RAC-alpha serine/threonine-protein kinase isoform X1. (480 aa)
SOS2Son of sevenless-like protein 2. (1332 aa)
LOC105095080Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
FOSProto-oncogene c-Fos. (380 aa)
POLKDNA polymerase kappa. (878 aa)
TGFB3Transforming growth factor beta-3 proprotein. (456 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
BAXApoptosis regulator BAX. (205 aa)
TCF7Transcription factor 7. (354 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (401 aa)
NRASGTPase NRas. (230 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
MAPK9Mitogen-activated protein kinase 9. (424 aa)
MYCMyc proto-oncogene protein. (438 aa)
RPS6KB1Ribosomal protein S6 kinase beta-1. (525 aa)
RHOATransforming protein RhoA. (193 aa)
MAPK10Mitogen-activated protein kinase 10. (474 aa)
APCAdenomatous polyposis coli protein. (2873 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa)
HRASGTPase HRas. (265 aa)
PIK3CBPhosphatidylinositol 4. (1070 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (271 aa)
GADD45BGrowth arrest and DNA damage-inducible protein GADD45 beta. (160 aa)
EGFPro-epidermal growth factor isoform X1. (1206 aa)
SMAD4Mothers against decapentaplegic-like protein 4. (552 aa)
MAPK3Mitogen-activated protein kinase 3. (377 aa)
TP53Cellular tumor antigen p53. (381 aa)
AXIN1Axin-1. (867 aa)
AKT2Cyclin N-terminal domain-containing protein 2. (481 aa)
TGFBR2TGF-beta receptor type-2. (532 aa)
TGFAProtransforming growth factor alpha. (159 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1. (433 aa)
RPS6KB2Ribosomal protein S6 kinase beta-2. (485 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
PIK3CDPhosphatidylinositol 4. (1044 aa)
RALBRas-related protein Ral-B. (206 aa)
SMAD2Mothers against decapentaplegic-like protein 2. (467 aa)
LEF1Lymphoid enhancer-binding factor 1. (414 aa)
RALARas-related protein Ral-A. (206 aa)
AKT3RAC-gamma serine/threonine-protein kinase isoform X3. (479 aa)
SOS1Son of sevenless-like protein 1. (1333 aa)
MLH1DNA mismatch repair protein Mlh1. (758 aa)
MAPK8Mitogen-activated protein kinase 8. (384 aa)
TGFBR1TGF-beta receptor type-1. (503 aa)
CASP3Caspase-3. (275 aa)
EGFREpidermal growth factor receptor. (1137 aa)
ARAFSerine/threonine-protein kinase A-Raf. (606 aa)
TGFB1Transforming growth factor beta-1 proprotein. (390 aa)
MTORSerine/threonine-protein kinase mTOR. (2546 aa)
TCF7L1Transcription factor 7-like 1. (547 aa)
TGFB2Transforming growth factor beta-2 proprotein. (442 aa)
GADD45GGrowth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa)
APPL1DCC-interacting protein 13-alpha. (708 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (668 aa)
BADBcl2-associated agonist of cell death isoform X1. (179 aa)
MSH3DNA mismatch repair protein Msh3 isoform X1. (1124 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (123 aa)
CASP9Caspase-9. (414 aa)
KRASGTPase KRas. (189 aa)
CTNNB1Catenin beta-1. (783 aa)
AXIN2Axin-2. (843 aa)
BCL2L11Bcl-2-like protein 11 isoform X6. (196 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (143 aa)
TCF7L2Transcription factor 7-like 2. (377 aa)
DCCDeleted in colorectal carcinoma. (1447 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
MAPK1Mitogen-activated protein kinase 1. (359 aa)
MSH2DNA mismatch repair protein Msh2. (937 aa)
MSH6DNA mismatch repair protein Msh6. (1363 aa)
Your Current Organism:
Camelus dromedarius
NCBI taxonomy Id: 9838
Other names: Arabian camel, C. dromedarius, camel, dromedaries, dromedary, dromedary camel, one-humped camel
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