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| | RGE_00660 | Putative oxidoreductase. (469 aa) |
| | garR | 2-hydroxy-3-oxopropionate reductase GarR. (296 aa) |
| | gdhA | Glutamate dehydrogenase GdhA; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (424 aa) |
| | mmsA | Methylmalonate-semialdehyde dehydrogenase MmsA. (506 aa) |
| | RGE_01420 | Phosphate acetyl/butyryl transferase family protein. (483 aa) |
| | ackA | Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (438 aa) |
| | RGE_01440 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | paaH | 3-hydroxyacyl-CoA dehydrogenase PaaH. (304 aa) |
| | ilvE | Branched-chain amino acid aminotransferase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa) |
| | RGE_02820 | Pyruvate ferredoxin/flavodoxin oxidoreductase. (1188 aa) |
| | RGE_03800 | Iron-containing alcohol dehydrogenase. (438 aa) |
| | RGE_03880 | Phosphate acetyl/butyryl transferase family protein. (468 aa) |
| | ackA-2 | Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (393 aa) |
| | maeB | Malate dehydrogenase MaeB. (775 aa) |
| | pflB | Formate acetyltransferase PflB. (751 aa) |
| | pflA | Pyruvate formate-lyase activating enzyme PflA; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (252 aa) |
| | RGE_06490 | enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa) |
| | RGE_06500 | Hypothetical protein. (95 aa) |
| | gltB | NAD(P)H-dependent glutamate synthase large subunit GltB. (1578 aa) |
| | gltD | NAD(P)H-dependent glutamate synthase small subunit GltD. (488 aa) |
| | RGE_09140 | acyl-CoA dehydrogenase. (595 aa) |
| | RGE_09160 | 3-hydroxyacyl-CoA dehydrogenase. (798 aa) |
| | fadA | Thiolase family protein FadA; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa) |
| | paaG | enoyl-CoA hydratase/isomerase. (257 aa) |
| | leuA | 2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (558 aa) |
| | phbA | acetyl-CoA acetyltransferase PhbA; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | ackA-3 | Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (407 aa) |
| | pta | Phosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (686 aa) |
| | ldh | L-lactate dehydrogenase Ldh; Belongs to the LDH/MDH superfamily. (308 aa) |
| | RGE_11660 | acetyl-CoA hydrolase. (504 aa) |
| | acnB | Aconitate hydrase 2 AcnB; Belongs to the aconitase/IPM isomerase family. (863 aa) |
| | mdh | Malate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa) |
| | sdhC | Succinate dehydrogenase cytochrome b556 subunit SdhC. (140 aa) |
| | sdhD | Succinate dehydrogenase hydrophobic membrane anchor subunit SdhD. (120 aa) |
| | sdhA | Succinate dehydrogenase flavoprotein subunit SdhA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (597 aa) |
| | sdhB | Succinate dehydrogenase iron-sulfur subunit SdhB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (234 aa) |
| | gltA | Citrate synthase GltA; Belongs to the citrate synthase family. (436 aa) |
| | sucD | succinyl-CoA ligase[ADP-forming] subunit alpha SucD; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (297 aa) |
| | sucC | succinyl-CoA ligase[ADP-forming] subunit bata SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa) |
| | RGE_12380 | methylmalonyl-CoA mutase. (723 aa) |
| | argK | Arginine/ornithine transport system ATPase ArgK. (326 aa) |
| | accA | Carboxyl transferase. (510 aa) |
| | RGE_12410 | Biotin carboxylase. (676 aa) |
| | leuC | 3-isopropylmalate dehydratase large LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (484 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa) |
| | leuB | 3-isopropylmalate dehydrogenase LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (363 aa) |
| | RGE_14070 | Putative acyl-CoA dehydrogenase. (375 aa) |
| | RGE_14080 | Putative acyl-CoA dehydrogenase. (391 aa) |
| | RGE_14520 | Hypothetical protein. (706 aa) |
| | RGE_15970 | AMP-dependent synthetase and ligase. (548 aa) |
| | RGE_15980 | enoyl-CoA hydratase/isomerase. (264 aa) |
| | RGE_15990 | Peptidase S9C family protein. (669 aa) |
| | RGE_16000 | Putative electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (558 aa) |
| | pflB-2 | Formate acetyltransferase PflB. (748 aa) |
| | pflA-2 | Pyruvate formate-lyase activating enzyme PflA; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (272 aa) |
| | ackA-4 | Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (420 aa) |
| | ilvD | Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. (619 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (864 aa) |
| | acsA | Acetyl-coenzyme A synthetase AcsA; Protein synonym:acetate--CoA ligase; protein synonym:acyl-activating enzyme. (571 aa) |
| | RGE_18620 | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa) |
| | acsA-2 | Acetyl-coenzyme A synthetase AcsA; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa) |
| | RGE_20970 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1665 aa) |
| | RGE_21080 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | RGE_21100 | Putative acyl-CoA dehydrogenase. (415 aa) |
| | RGE_21120 | acyl-CoA dehydrogenase. (376 aa) |
| | ppdK | Pyruvate phosphate dikinase PpdK; Belongs to the PEP-utilizing enzyme family. (907 aa) |
| | pyc | Pyruvate carboxylase Pyc; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1162 aa) |
| | frdD | Fumarate reductase subunit D FrdD; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdD family. (118 aa) |
| | frdC | Fumarate reductase subunit C FrdC. (131 aa) |
| | frdB | Fumarate reductase iron-sulfur subunit FrdB. (259 aa) |
| | frdA | Fumarate reductase flavoprotein subunit FrdA. (589 aa) |
| | RGE_22610 | Putative pyruvate kinase. (619 aa) |
| | RGE_23040 | Alcohol dehydrogenase. (349 aa) |
| | aceE-2 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (900 aa) |
| | aceF | Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (563 aa) |
| | lpdA | Dihydrolipoamide dehydrogenase LpdA; Protein synonym:pyruvate dehydrogenase E3 component. (581 aa) |
| | RGE_24070 | acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa) |
| | RGE_24380 | 3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (702 aa) |
| | RGE_24390 | Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | RGE_24400 | acyl-CoA dehydrogenase domain protein. (593 aa) |
| | xsc | Sulfoacetaldehyde acetyltransferase Xsc; Belongs to the TPP enzyme family. (570 aa) |
| | RGE_25310 | Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa) |
| | ldh-2 | L-lactate dehydrogenase Ldh; Catalyzes the conversion of lactate to pyruvate. (303 aa) |
| | RGE_26220 | Beta-alanine-pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (435 aa) |
| | ppsA | Phosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (798 aa) |
| | RGE_27230 | Putative phosphotransferase; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (274 aa) |
| | odhL | 2-oxoglutarate dehydrogenase E3 component OdhL. (472 aa) |
| | odhB | 2-oxoglutarate dehydrogenase E2 component OdhB; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (420 aa) |
| | odhA | 2-oxoglutarate dehydrogenase E1 component OdhA. (952 aa) |
| | RGE_27790 | acyl-CoA dehydrogenase. (591 aa) |
| | etfL | Electron transfer flavoprotein alpha-subunit EtfL. (310 aa) |
| | etfS | Electron transfer flavoprotein beta-subunit EtfS. (249 aa) |
| | leuA-2 | 2-isopropylmalate synthase,LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (513 aa) |
| | ilvC | Ketol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | ilvH | Protein synonym:acetohydroxy-acid synthase small subunit. (163 aa) |
| | ilvI | Protein synonym:acetolactate synthase I/II/III large subunit. (590 aa) |
| | fumC | Fumarate hydratase class II FumC; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) |
| | porC | Pyruvate ferredoxin oxidoreductase gamma subunit PorC. (193 aa) |
| | porA | Pyruvate ferredoxin oxidoreductase alpha subunit PorA. (417 aa) |
| | porB | Pyruvate ferredoxin oxidoreductase beta subunit PorB. (302 aa) |
| | porD | Putative pyruvate ferredoxin oxidoreductase delta subunit PorD. (541 aa) |
| | RGE_29210 | Transcriptional regulator, Crp/Fnr family. (234 aa) |
| | RGE_29220 | Phosphotransferase enzyme family protein. (358 aa) |
| | RGE_29230 | Putative acyl-CoA dehydrogenase. (408 aa) |
| | RGE_29810 | Citrate synthase family protein. (259 aa) |
| | RGE_30830 | Aspartate aminotransferase. (408 aa) |
| | icd | Isocitrate dehydrogenase [NADP] Icd. (418 aa) |
| | RGE_32390 | Protein synonym:acetohydroxy-acid synthase large subunit; Belongs to the TPP enzyme family. (566 aa) |
| | RGE_32600 | Aminotransferase. (410 aa) |
| | prpE | propionate--CoA ligase PrpE. (633 aa) |
| | RGE_32660 | Alcohol dehydrogenase, zinc-binding. (330 aa) |
| | RGE_35280 | Phosphate acetyl/butyryl transferase family protein. (466 aa) |
| | dld | D-lactate dehydrogenase Dld; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (581 aa) |
| | lldD | L-lactate dehydrogenase cytochrome LldD; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. (379 aa) |
| | RGE_35630 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | lldA | L-lactate dehydrogenase LldA. (384 aa) |
| | RGE_37010 | Protein synonym:acetohydroxy-acid synthase large subunit; Belongs to the TPP enzyme family. (584 aa) |
| | acnA | Aconitate hydrase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (909 aa) |
| | adhB | Iron-containing alcohol dehydrogenase AdhB. (383 aa) |
| | RGE_39930 | AMP-dependent synthetase and ligase. (542 aa) |
| | yeaU | Tartrate dehydrogenase YeaU. (359 aa) |
| | paaG-2 | enoyl-CoA hydratase/isomerase PaaG; Belongs to the enoyl-CoA hydratase/isomerase family. (264 aa) |
| | nifV | Homocitrate synthase NifV; Belongs to the alpha-IPM synthase/homocitrate synthase family. (386 aa) |
| | fixA | Putative electron transfer flavoprotein beta-subunit FixA. (282 aa) |
| | fixB | Putative electron transfer flavoprotein alpha-subunit FixB. (366 aa) |
| | fixC | Putative electron transfer flavoprotein ubiquinone oxidoreductase (ETF-QO) subunit FixC; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (435 aa) |
| | fixX | Electron transfer flavoprotein ubiquinone oxidoreductase (ETF-QO) subunit FixX; Could be a 3Fe-4S cluster-containing protein. (99 aa) |
| | RGE_43370 | Thioredoxin domain protein, DsbA family. (189 aa) |
| | RGE_43380 | Hypothetical protein. (61 aa) |
| | RGE_43390 | Hypothetical protein. (166 aa) |
| | RGE_43400 | Putative hydroxymethylglutaryl-CoA lyase. (305 aa) |
| | mccA | 3-methylcrotonoyl-CoA carboxylase, alpha subunit MccA; Protein synonym:biotin carboxylase. (668 aa) |
| | RGE_43420 | Hypothetical protein. (198 aa) |
| | RGE_43430 | enoyl-CoA hydratase/isomerase. (260 aa) |
| | RGE_43440 | Hypothetical protein. (178 aa) |
| | RGE_43450 | Carboxyl transferase. (536 aa) |
| | RGE_43520 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | ivd | Putative isovaleryl-CoA dehydrogenase. (392 aa) |
| | icmF-2 | methylmalonyl-CoA mutase, putative; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1105 aa) |
| | maeB-2 | Malate dehydrogenase MaeB. (764 aa) |
| | sucD-2 | succinyl-CoA ligase[ADP-forming] subunit alpha SucD; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (297 aa) |
| | sucC-2 | succinyl-CoA ligase[ADP-forming] subunit bata SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa) |
