STRINGSTRING
menD menD tkt-2 tkt-2 RGE_37010 RGE_37010 tkt tkt RGE_32390 RGE_32390 ilvI ilvI ilvH ilvH xsc xsc dxs dxs tal tal
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase MenD; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (600 aa)
tkt-2Transketolase Tkt; Belongs to the transketolase family. (675 aa)
RGE_37010Protein synonym:acetohydroxy-acid synthase large subunit; Belongs to the TPP enzyme family. (584 aa)
tktTransketolase Tkt; Belongs to the transketolase family. (667 aa)
RGE_32390Protein synonym:acetohydroxy-acid synthase large subunit; Belongs to the TPP enzyme family. (566 aa)
ilvIProtein synonym:acetolactate synthase I/II/III large subunit. (590 aa)
ilvHProtein synonym:acetohydroxy-acid synthase small subunit. (163 aa)
xscSulfoacetaldehyde acetyltransferase Xsc; Belongs to the TPP enzyme family. (570 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (628 aa)
talTransaldolase B Tal; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa)
Your Current Organism:
Rubrivivax gelatinosus
NCBI taxonomy Id: 983917
Other names: R. gelatinosus IL144, Rubrivivax gelatinosus IL144, Rubrivivax gelatinosus str. IL144, Rubrivivax gelatinosus strain IL144
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