STRINGSTRING
aroG aroG putA putA dapF dapF lysA lysA aroK aroK aroB aroB gltB gltB RGE_10900 RGE_10900 aroG-2 aroG-2 mdh mdh RGE_12300 RGE_12300 asd asd folC folC kynU kynU folK folK pheA pheA aroQ aroQ aroC aroC RGE_17900 RGE_17900 RGE_19020 RGE_19020 RGE_19320 RGE_19320 frdD frdD dapE dapE dapD dapD dapC dapC speB speB RGE_26620 RGE_26620 fumC fumC lysC lysC nadA nadA folP folP dapA dapA ppc ppc hutH hutH hutU hutU hutI hutI aroE aroE dapB dapB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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aroG3-deoxy-D-arabinoheptulosonate-7-phosphate synthase AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (378 aa)
putAProline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (999 aa)
dapFDiaminopimelate epimerase DapF; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (281 aa)
lysADiaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (424 aa)
aroKShikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (192 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
gltBNAD(P)H-dependent glutamate synthase large subunit GltB. (1578 aa)
RGE_10900Hypothetical protein. (172 aa)
aroG-23-deoxy-D-arabinoheptulosonate-7-phosphate synthase AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (373 aa)
mdhMalate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
RGE_12300Hypothetical protein. (93 aa)
asdAspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (377 aa)
folCBifunctional folylpolyglutamate synthase and dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (427 aa)
kynUKynureninase KynU; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (419 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. (157 aa)
pheAChorismate mutase/prephenate dehydratase PheA; Bifunctional protein; protein synonym:P-protein. (368 aa)
aroQ3-dehydroquinate dehydratase AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (150 aa)
aroCChorismate synthase AroC; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (369 aa)
RGE_17900Hypothetical protein. (411 aa)
RGE_19020Peptidase M20A family protein. (580 aa)
RGE_19320Putative hydrolase. (442 aa)
frdDFumarate reductase subunit D FrdD; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdD family. (118 aa)
dapESuccinyl-diaminopimelate desuccinylase DapE; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (381 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase DapD; Belongs to the transferase hexapeptide repeat family. (273 aa)
dapCAcetylornithine/succinyldiaminopimelate aminotransferase DapC; Bifunctional protein. (398 aa)
speBAgmatinase SpeB; Protein synonym:agmatine ureohydrolase; Belongs to the arginase family. (326 aa)
RGE_26620Pterin-binding domain-containing protein. (458 aa)
fumCFumarate hydratase class II FumC; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
lysCAspartokinase LysC; Protein synonym:aspartate kinase; Belongs to the aspartokinase family. (424 aa)
nadAQuinolinate synthetase NadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (372 aa)
folPDihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (285 aa)
dapADihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa)
ppcPhosphoenolpyruvate carboxylase Ppc; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (943 aa)
hutHHistidine ammonia-lyase HutH; Protein synonym:histidase. (516 aa)
hutUUrocanate hydratase HutU; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (563 aa)
hutIImidazolonepropionase HutI; Protein synonym:imidazolone-5-propionate hydrolase. (400 aa)
aroEShikimate dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa)
dapBDihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa)
Your Current Organism:
Rubrivivax gelatinosus
NCBI taxonomy Id: 983917
Other names: R. gelatinosus IL144, Rubrivivax gelatinosus IL144, Rubrivivax gelatinosus str. IL144, Rubrivivax gelatinosus strain IL144
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