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ubiA | 4-hydroxybenzoate octaprenyltransferase UbiA; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (294 aa) | ||||
hpd | 4-hydroxyphenylpyruvate dioxygenase Hpd. (364 aa) | ||||
menH | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase MenH. (254 aa) | ||||
menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase MenD; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (600 aa) | ||||
menF | Isochorismate synthase MenF. (427 aa) | ||||
coq7 | 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase Coq7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. (213 aa) | ||||
ubiE | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (243 aa) | ||||
ubiG | 3-demethylubiquinone-9 3-methyltransferase UbiG; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (234 aa) | ||||
RGE_20750 | NmrA family protein. (296 aa) | ||||
RGE_21380 | Thioesterase superfamily protein. (142 aa) | ||||
RGE_23910 | NAD(P)H dehydrogenase, quinone family. (259 aa) | ||||
RGE_29320 | Hypothetical protein. (161 aa) | ||||
ubiE-2 | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa) | ||||
menA | 1,4-Dihydroxy-2-naphtoate prenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (296 aa) | ||||
menE | O-succinylbenzoate-CoA ligase MenE. (441 aa) | ||||
menB | Naphthoate synthase MenB; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (280 aa) | ||||
RGE_38580 | Endoribonuclease L-PSP. (343 aa) | ||||
ubiD | 3-polyprenyl-4-hydroxybenzoate decarboxylase UbiD; Belongs to the UbiD family. (517 aa) | ||||
ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (188 aa) | ||||
ubiH | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family. (383 aa) |