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aroG aroG tyrB tyrB trpE trpE trpG trpG trpD trpD trpC trpC aroK aroK aroB aroB hisC hisC aroG-2 aroG-2 trpF trpF trpB trpB trpA trpA aroA aroA tyrA tyrA pheA pheA aroQ aroQ RGE_15380 RGE_15380 aroC aroC hisC-2 hisC-2 trpB-2 trpB-2 RGE_28890 RGE_28890 RGE_30830 RGE_30830 RGE_38580 RGE_38580 aroE aroE phhA phhA trpF-2 trpF-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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aroG3-deoxy-D-arabinoheptulosonate-7-phosphate synthase AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (378 aa)
tyrBAromatic amino acid aminotransferase TyrB. (398 aa)
trpEAnthranilate synthase component I TrpE; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high con [...] (491 aa)
trpGAnthranilate synthase component II TrpG. (196 aa)
trpDAnthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa)
trpCIndole-3-glycerol phosphate synthase TrpC; Protein synonym:IGPS; Belongs to the TrpC family. (262 aa)
aroKShikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (192 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
hisCHistidinol-phosphate aminotransferase HisC; Protein synonym:imidazole acetol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (362 aa)
aroG-23-deoxy-D-arabinoheptulosonate-7-phosphate synthase AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (373 aa)
trpFProtein synonym:phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (210 aa)
trpBTryptophan synthase beta chain TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (415 aa)
trpATryptophan synthase alpha chain TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. (678 aa)
tyrAPrephenate dehydrogenase TyrA. (293 aa)
pheAChorismate mutase/prephenate dehydratase PheA; Bifunctional protein; protein synonym:P-protein. (368 aa)
aroQ3-dehydroquinate dehydratase AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (150 aa)
RGE_15380Aminotransferase. (400 aa)
aroCChorismate synthase AroC; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (369 aa)
hisC-2Histidinol-phosphate aminotransferase HisC; Protein synonym:imidazole acetol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (363 aa)
trpB-2Putative tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (452 aa)
RGE_28890Putative aminotransferase. (323 aa)
RGE_30830Aspartate aminotransferase. (408 aa)
RGE_38580Endoribonuclease L-PSP. (343 aa)
aroEShikimate dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa)
phhAPhenylalanine-4-hydroxylase PhhA. (317 aa)
trpF-2Putative N-(5'phosphoribosyl)anthranilate isomerase TrpF; Belongs to the TrpF family. (218 aa)
Your Current Organism:
Rubrivivax gelatinosus
NCBI taxonomy Id: 983917
Other names: R. gelatinosus IL144, Rubrivivax gelatinosus IL144, Rubrivivax gelatinosus str. IL144, Rubrivivax gelatinosus strain IL144
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