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ilvE ilvE kdtB kdtB RGE_12190 RGE_12190 apbA apbA ilvD ilvD panB panB panC panC apbA-2 apbA-2 ilvC ilvC ilvH ilvH ilvI ilvI apbA-3 apbA-3 RGE_32390 RGE_32390 coaBC coaBC RGE_37010 RGE_37010 acpS acpS coaE coaE coaX coaX
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ilvEBranched-chain amino acid aminotransferase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa)
kdtBPantetheine-phosphate adenylyltransferase KdtB; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa)
RGE_12190Putative aminotransferase. (311 aa)
apbA2-dehydropantoate 2-reductase ApbA. (335 aa)
ilvDDihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. (619 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (282 aa)
panCPantothenate synthetase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa)
apbA-22-dehydropantoate 2-reductase ApbA; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa)
ilvCKetol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
ilvHProtein synonym:acetohydroxy-acid synthase small subunit. (163 aa)
ilvIProtein synonym:acetolactate synthase I/II/III large subunit. (590 aa)
apbA-32-dehydropantoate 2-reductase ApbA; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (326 aa)
RGE_32390Protein synonym:acetohydroxy-acid synthase large subunit; Belongs to the TPP enzyme family. (566 aa)
coaBCPhosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase CoaB/CoaC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa)
RGE_37010Protein synonym:acetohydroxy-acid synthase large subunit; Belongs to the TPP enzyme family. (584 aa)
acpSHolo-[acyl-carrier-protein] synthase AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (140 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (208 aa)
coaXType III pantothenate kinase CoaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (252 aa)
Your Current Organism:
Rubrivivax gelatinosus
NCBI taxonomy Id: 983917
Other names: R. gelatinosus IL144, Rubrivivax gelatinosus IL144, Rubrivivax gelatinosus str. IL144, Rubrivivax gelatinosus strain IL144
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