(101 nodes) Glutathione metabolism network (Trichoderma harzianum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2T3ZZP7	Uncharacterized protein. (1281 aa)
	A0A2T3ZZJ2	Uncharacterized protein; Belongs to the GST superfamily. (252 aa)
	A0A2T3ZXH8	Uncharacterized protein. (258 aa)
	A0A2T3ZX32	NmrA domain-containing protein. (343 aa)
	A0A2T3ZWD8	Uncharacterized protein. (910 aa)
	A0A2T3ZVX2	Uncharacterized protein; Belongs to the GST superfamily. (255 aa)
	A0A2T3ZVM4	Uncharacterized protein. (415 aa)
	A0A2T3ZV90	Uncharacterized protein; Belongs to the GST superfamily. (233 aa)
	A0A2T3ZU38	LigB domain-containing protein. (292 aa)
	A0A2T3ZTY6	Thioredoxin domain-containing protein. (1107 aa)
	A0A2T3ZT94	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
	A0A2T3ZSG2	Uncharacterized protein. (216 aa)
	A0A2T3ZSC8	Uncharacterized protein; Belongs to the GST superfamily. (271 aa)
	A0A2T3ZRW4	Uncharacterized protein; Belongs to the GST superfamily. (226 aa)
	A0A2T3ZRV7	Uncharacterized protein. (293 aa)
	A0A2T3ZRF7	Uncharacterized protein. (260 aa)
	A0A2T3ZRC7	Uncharacterized protein. (224 aa)
	A0A2T4AP60	Uncharacterized protein. (251 aa)
	A0A2T4ANC4	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (503 aa)
	A0A2T4AN56	Uncharacterized protein; Belongs to the GST superfamily. (230 aa)
	A0A2T4AN37	Uncharacterized protein; Belongs to the GST superfamily. (214 aa)
	A0A2T4AN27	Uncharacterized protein; Belongs to the GST superfamily. (223 aa)
	A0A2T4AN21	Uncharacterized protein; Belongs to the GST superfamily. (202 aa)
	A0A2T4AMT6	Uncharacterized protein; Belongs to the GST superfamily. (235 aa)
	A0A2T4AMS3	GST C-terminal domain-containing protein. (58 aa)
	A0A2T4AMR5	Uncharacterized protein. (145 aa)
	A0A2T4AMQ9	GST N-terminal domain-containing protein. (144 aa)
	A0A2T4AMH9	Uncharacterized protein. (338 aa)
	A0A2T4ALZ0	Uncharacterized protein. (1360 aa)
	A0A2T4ALJ7	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (171 aa)
	A0A2T4AL91	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (448 aa)
	A0A2T4AKQ6	Peroxidase; Belongs to the peroxidase family. (354 aa)
	A0A2T4AK76	Glutaredoxin domain-containing protein. (278 aa)
	A0A2T4AJU4	Uncharacterized protein. (582 aa)
	A0A2T4AJG6	Uncharacterized protein. (307 aa)
	A0A2T4AIV4	Uncharacterized protein; Belongs to the GST superfamily. (278 aa)
	A0A2T4AI04	Uncharacterized protein. (407 aa)
	A0A2T4AHS8	F-box domain-containing protein. (679 aa)
	A0A2T4AHM9	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (469 aa)
	A0A2T4AHH8	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (903 aa)
	A0A2T4AH65	Uncharacterized protein; Belongs to the GST superfamily. (313 aa)
	A0A2T4AGW9	Uncharacterized protein. (228 aa)
	A0A2T4AGD1	Uncharacterized protein. (253 aa)
	M431DRAFT_4832	Uncharacterized protein. (192 aa)
	A0A2T4ADW5	Uncharacterized protein. (509 aa)
	A0A2T4ACQ6	Zn(2)-C6 fungal-type domain-containing protein. (513 aa)
	A0A2T4AC60	Uncharacterized protein. (348 aa)
	A0A2T4AC14	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
	A0A2T4ABX1	Uncharacterized protein. (392 aa)
	A0A2T4ABQ4	Uncharacterized protein. (606 aa)
	M431DRAFT_5140	GST N-terminal domain-containing protein; Belongs to the GST superfamily. (240 aa)
	A0A2T4AA68	Uncharacterized protein; Belongs to the GST superfamily. (259 aa)
	A0A2T4AA48	Uncharacterized protein. (454 aa)
	A0A2T4A9B6	Aminopeptidase. (886 aa)
	A0A2T4A8T7	Uncharacterized protein; Belongs to the GST superfamily. (202 aa)
	A0A2T4A8B2	Uncharacterized protein. (286 aa)
	A0A2T4A7P2	Uncharacterized protein; Belongs to the GST superfamily. (216 aa)
	A0A2T4A7E1	Uncharacterized protein; Belongs to the GST superfamily. (233 aa)
	A0A2T4A7D7	Uncharacterized protein; Belongs to the GST superfamily. (209 aa)
	A0A2T4A794	Uncharacterized protein. (687 aa)
	A0A2T4A768	GST C-terminal domain-containing protein. (339 aa)
	A0A2T4A706	Uncharacterized protein; Belongs to the GST superfamily. (217 aa)
	A0A2T4A6W5	Uncharacterized protein; Belongs to the GST superfamily. (237 aa)
	A0A2T4A4Q8	Uncharacterized protein. (230 aa)
	A0A2T4A4K5	Uncharacterized protein. (208 aa)
	A0A2T4A4I4	Uncharacterized protein. (173 aa)
	M431DRAFT_8275	GST N-terminal domain-containing protein. (109 aa)
	M431DRAFT_8223	Uncharacterized protein; Belongs to the GST superfamily. (215 aa)
	A0A2T4A3X3	Uncharacterized protein. (524 aa)
	A0A2T4A3S7	GGACT domain-containing protein. (211 aa)
	A0A2T4A3K0	GGACT domain-containing protein. (330 aa)
	A0A2T4A349	Uncharacterized protein. (572 aa)
	A0A2T4A2V2	Glutaredoxin domain-containing protein. (104 aa)
	A0A2T4A2D0	Aminopeptidase. (886 aa)
	A0A2T4A2C4	Uncharacterized protein. (145 aa)
	A0A2T4A257	Uncharacterized protein; Belongs to the GST superfamily. (252 aa)
	A0A2T4A1X1	Uncharacterized protein. (150 aa)
	A0A2T4A1R6	Uncharacterized protein; Belongs to the GST superfamily. (223 aa)
	A0A2T4A1N9	Uncharacterized protein. (283 aa)
	A0A2T4A1J1	Uncharacterized protein. (460 aa)
	A0A2T4A0I6	Aminopeptidase. (884 aa)
	A0A2T4A063	F-box domain-containing protein. (348 aa)
	A0A2T3ZZJ7	Uncharacterized protein; Belongs to the GST superfamily. (228 aa)
	M431DRAFT_132	NmrA domain-containing protein. (343 aa)
	A0A2T4ASG9	NmrA domain-containing protein. (336 aa)
	A0A2T4AS48	Uncharacterized protein; Belongs to the GST superfamily. (489 aa)
	M431DRAFT_2340	Uncharacterized protein. (154 aa)
	A0A2T4ARL8	M20_dimer domain-containing protein. (476 aa)
	A0A2T4ARJ8	CsbD domain-containing protein. (181 aa)
	A0A2T4ARH9	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (292 aa)
	A0A2T4ARG8	Aldo_ket_red domain-containing protein. (309 aa)
	M431DRAFT_2183	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (504 aa)
	A0A2T4ARD5	Uncharacterized protein. (719 aa)
	A0A2T4AR65	DSBA domain-containing protein. (235 aa)
	A0A2T4AR22	Uncharacterized protein. (231 aa)
	M431DRAFT_2093	Glutathione synthetase. (516 aa)
	A0A2T4AQR4	Zn(2)-C6 fungal-type domain-containing protein. (466 aa)
	A0A2T4AQN8	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (231 aa)
	A0A2T4AQ65	Uncharacterized protein. (593 aa)
	A0A2T4AQ37	Uncharacterized protein; Belongs to the GST superfamily. (208 aa)
	A0A2T4AP83	Uncharacterized protein. (197 aa)

Your Current Organism:

Trichoderma harzianum

NCBI taxonomy Id: 983964
Other names: Hypocrea lixii CBS 226.95, T. harzianum CBS 226.95, Trichoderma harzianum CBS 226.95

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2T3ZRC7	A0A2T3ZSC8	A0A2T3ZRC7	A0A2T3ZSC8	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.616
A0A2T3ZRC7	A0A2T3ZTY6	A0A2T3ZRC7	A0A2T3ZTY6	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.492
A0A2T3ZRC7	A0A2T3ZVX2	A0A2T3ZRC7	A0A2T3ZVX2	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.548
A0A2T3ZRC7	A0A2T3ZXH8	A0A2T3ZRC7	A0A2T3ZXH8	Uncharacterized protein.	Uncharacterized protein.	0.550
A0A2T3ZRC7	A0A2T4A1X1	A0A2T3ZRC7	A0A2T4A1X1	Uncharacterized protein.	Uncharacterized protein.	0.638
A0A2T3ZRC7	A0A2T4A349	A0A2T3ZRC7	A0A2T4A349	Uncharacterized protein.	Uncharacterized protein.	0.497
A0A2T3ZRC7	A0A2T4A4K5	A0A2T3ZRC7	A0A2T4A4K5	Uncharacterized protein.	Uncharacterized protein.	0.550
A0A2T3ZRC7	A0A2T4A6W5	A0A2T3ZRC7	A0A2T4A6W5	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.442
A0A2T3ZRC7	A0A2T4A7E1	A0A2T3ZRC7	A0A2T4A7E1	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.599
A0A2T3ZRC7	A0A2T4AA68	A0A2T3ZRC7	A0A2T4AA68	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.516
A0A2T3ZRC7	A0A2T4ABQ4	A0A2T3ZRC7	A0A2T4ABQ4	Uncharacterized protein.	Uncharacterized protein.	0.497
A0A2T3ZRC7	A0A2T4AH65	A0A2T3ZRC7	A0A2T4AH65	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.411
A0A2T3ZRC7	A0A2T4AHM9	A0A2T3ZRC7	A0A2T4AHM9	Uncharacterized protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.764
A0A2T3ZRC7	A0A2T4AIV4	A0A2T3ZRC7	A0A2T4AIV4	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.516
A0A2T3ZRC7	A0A2T4AJU4	A0A2T3ZRC7	A0A2T4AJU4	Uncharacterized protein.	Uncharacterized protein.	0.497
A0A2T3ZRC7	A0A2T4ALJ7	A0A2T3ZRC7	A0A2T4ALJ7	Uncharacterized protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.419
A0A2T3ZRC7	A0A2T4AN56	A0A2T3ZRC7	A0A2T4AN56	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.451
A0A2T3ZRC7	A0A2T4AQ65	A0A2T3ZRC7	A0A2T4AQ65	Uncharacterized protein.	Uncharacterized protein.	0.497
A0A2T3ZRC7	A0A2T4AS48	A0A2T3ZRC7	A0A2T4AS48	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.431
A0A2T3ZRC7	M431DRAFT_2093	A0A2T3ZRC7	A0A2T4AQZ2	Uncharacterized protein.	Glutathione synthetase.	0.774