(126 nodes) Nucleolus network (Drechmeria coniospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCS_06030	SIK1-like protein. (508 aa)
	DCS_06186	Brix domain-containing protein 2. (540 aa)
	DCS_06256	Eukaryotic rRNA processing. (402 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (836 aa)
	DCS_06272	Ribosomal RNA-processing protein 17. (215 aa)
	DCS_06395	Nucleolar protein NOP52 variant. (262 aa)
	DCS_06410	Brix domain-containing protein. (465 aa)
	DCS_06409	Putative DEAD box protein; Belongs to the DEAD box helicase family. (488 aa)
	DCS_06511	Fcf2 domain-containing protein. (189 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1072 aa)
	DCS_06632	Putative MRD1. (848 aa)
	DCS_06623	WD repeat-containing protein 75. (965 aa)
	DCS_06633	TEA domain-containing protein. (874 aa)
	DCS_06641	ATP-dependent RNA helicase ROK1. (757 aa)
	DCS_06801	Uncharacterized protein. (423 aa)
	DCS_06764	Armadillo-type fold protein. (786 aa)
	DCS_06841	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (125 aa)
	DCS_06880	WD repeat protein. (642 aa)
	DCS_06948	U3 small nucleolar RNA-associated protein 14. (887 aa)
	DCS_07157	Protein BFR2. (571 aa)
	DCS_07281	RNA helicase. (629 aa)
	DCS_07294	Nucleolar protein NOP58-like protein. (563 aa)
	DCS_07408	Nucleolar GTP-binding protein 2. (550 aa)
	DCS_07409	Uncharacterized protein; Belongs to the RNR ribonuclease family. (982 aa)
	DCS_07420	Brix domain-containing protein. (320 aa)
	DCS_07463	Pumilio domain-containing protein. (691 aa)
	DCS_07456	Ribosome biogenesis protein NSA2. (260 aa)
	DCS_07503	Uncharacterized protein. (248 aa)
	DCS_07494	RNA-3'-phosphate cyclase family protein. (403 aa)
	DCS_07737	tRNA-methyltransferase NCL1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (679 aa)
	DCS_07791	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (670 aa)
	DCS_07790	Brix domain containing protein. (412 aa)
	DCS_07908	Helicase. (777 aa)
	DCS_07922	CCAAT-box-binding transcription factor. (971 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (749 aa)
	DCS_08023	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (588 aa)
	DCS_08167	ATP-dependent RNA helicase DOB1. (1103 aa)
	DCS_03424	Dependent RNA helicase drs-1; Belongs to the DEAD box helicase family. (786 aa)
	DCS_03458	Uncharacterized protein. (165 aa)
	DCS_03575	WD_REPEATS_REGION domain-containing protein. (1120 aa)
	DCS_03605	ATP-dependent RNA helicase dbp9. (620 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (647 aa)
	DCS_03694	3' exoribonuclease. (228 aa)
	DCS_03832	zf-LYAR domain-containing protein. (399 aa)
	DCS_03815	rRNA biogenesis protein RRP36. (311 aa)
	DCS_03861	WD domain-containing protein. (1134 aa)
	DCS_03797	Periodic tryptophan protein 2. (888 aa)
	DCS_03873	Ribosome biogenesis protein Noc4. (540 aa)
	DCS_03897	Nucleolar protein 12. (539 aa)
	DCS_03970	60S ribosome biogenesis protein Mak11. (488 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (474 aa)
	DCS_04322	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (269 aa)
	DCS_04353	ATP-dependent RNA helicase dbp3; Belongs to the DEAD box helicase family. (596 aa)
	DCS_04336	Uncharacterized protein. (575 aa)
	DCS_04373	rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (120 aa)
	DCS_04549	Ribosome assembly protein Noc2. (778 aa)
	DCS_04571	Wdr1p. (870 aa)
	DCS_04790	NOL1/NOP2/sun domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (545 aa)
	DCS_04824	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (188 aa)
	DCS_04922	RNase_PH domain-containing protein. (333 aa)
	DCS_04970	RNase_PH domain-containing protein. (270 aa)
	DCS_05039	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (726 aa)
	DCS_05114	RNA helicase. (576 aa)
	DCS_05240	Nucleolar protein. (907 aa)
	DCS_05225	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (197 aa)
	DCS_05344	U3 small nucleolar ribonucleoprotein IMP4. (298 aa)
	DCS_05414	Small nucleolar ribonucleoprotein complex subunit. (552 aa)
	DCS_05491	Utp12 domain-containing protein. (408 aa)
	DCS_05427	RRM domain-containing protein. (367 aa)
	DCS_05572	DNA polymerase V family protein. (1064 aa)
	DCS_05576	Uncharacterized protein. (476 aa)
	DCS_05577	HEAT repeat protein. (2160 aa)
	DCS_05710	Exosomal core protein CSL4. (208 aa)
	DCS_05707	Sec2p domain-containing protein. (286 aa)
	DCS_05726	PINc domain-containing protein. (198 aa)
	DCS_00203	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family. (570 aa)
	DCS_00269	Sas10/Utp3/C1D-like protein. (373 aa)
	DCS_00399	Uncharacterized protein. (418 aa)
	DCS_00427	ATP-dependent RNA helicase mss116; Belongs to the DEAD box helicase family. (653 aa)
	DCS_00322	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (321 aa)
	DCS_00411	ATP-dependent RNA helicase DBP10. (885 aa)
	DCS_00456	U3 snoRNP-associated protein Esf2. (322 aa)
	DCS_00451	ATP-dependent RNA helicase DBP7; Belongs to the DEAD box helicase family. (742 aa)
	DCS_00517	WD repeat containing protein 36. (1087 aa)
	DCS_00555	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (653 aa)
	DCS_00518	Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (850 aa)
	DCS_00577	Ribosome biogenesis protein. (1033 aa)
	DCS_00771	Uncharacterized protein. (371 aa)
	DCS_00871	Importin N-terminal domain-containing protein. (1065 aa)
	DCS_00968	Sas10/Utp3/C1D family protein. (186 aa)
	DCS_00978	RRM domain-containing protein. (361 aa)
	DCS_01018	Uncharacterized protein. (245 aa)
	DCS_01130	Uncharacterized protein. (474 aa)
	DCS_01179	Uncharacterized protein. (307 aa)
	DCS_01116	Protein phosphatase; Belongs to the PP2C family. (728 aa)
	DCS_01221	U3 small nucleolar RNA-associated protein. (1804 aa)
	DCS_01166	Uncharacterized protein; Belongs to the DEAD box helicase family. (536 aa)
	DCS_01280	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (247 aa)
	DCS_01513	Putative 3'->5' exoribonuclease. (353 aa)
	DCS_01495	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (718 aa)
	DCS_01479	WD_REPEATS_REGION domain-containing protein. (529 aa)
	DCS_01634	Ribosomal protein S4/S9. (183 aa)
	DCS_01843	MIF4G domain-containing protein. (889 aa)
	DCS_01852	Uncharacterized protein. (549 aa)
	DCS_01836	U3 small nucleolar RNA-associated protein 22. (1133 aa)
	DCS_01868	Nucleolar essential protein 1. (261 aa)
	DCS_02102	Uncharacterized protein. (313 aa)
	DCS_02252	Uncharacterized protein. (802 aa)
	DCS_02322	U3 small nucleolar RNA associated protein. (445 aa)
	DCS_02451	Electron transfer flavoprotein alpha-subunit. (381 aa)
	DCS_02501	Pre-rRNA processing protein Esf1. (712 aa)
	DCS_02496	RNA helicase. (800 aa)
	DCS_02582	Sas10 domain-containing protein. (620 aa)
	DCS_02621	WD domain, G-beta repeat containing protein. (598 aa)
	DCS_02659	Ribonuclease II/R. (1355 aa)
	DCS_02687	Small nucleolar ribonucleoprotein complex subunit. (910 aa)
	DCS_02635	Uncharacterized protein. (205 aa)
	DCS_02698	DEAH-box RNA helicase. (1207 aa)
	DCS_02710	Uncharacterized protein. (315 aa)
	DCS_02744	Nucleolar protein 16. (238 aa)
	DCS_02792	Protein MAK16; Belongs to the MAK16 family. (309 aa)
	DCS_02891	Ribosomal RNA-processing protein 12. (1257 aa)
	DCS_02905	Uncharacterized protein. (696 aa)
	DCS_02982	Nucleic acid-binding, OB-fold-like protein. (1783 aa)
	DCS_03022	RNA recognition motif containing protein. (721 aa)
	DCS_03124	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (455 aa)

Your Current Organism:

Drechmeria coniospora

NCBI taxonomy Id: 98403
Other names: CBS 615.82, D. coniospora, Meria coniospora

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCS_00203	DCS_00269	A0A151GPQ6	A0A151GPV4	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Sas10/Utp3/C1D-like protein.	0.611
DCS_00203	DCS_00322	A0A151GPQ6	A0A151GQC1	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.923
DCS_00203	DCS_00399	A0A151GPQ6	A0A151GQ86	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.798
DCS_00203	DCS_00411	A0A151GPQ6	A0A151GQE7	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	ATP-dependent RNA helicase DBP10.	0.649
DCS_00203	DCS_00451	A0A151GPQ6	A0A151GQI5	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	ATP-dependent RNA helicase DBP7; Belongs to the DEAD box helicase family.	0.667
DCS_00203	DCS_00456	A0A151GPQ6	A0A151GQF1	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	U3 snoRNP-associated protein Esf2.	0.746
DCS_00203	DCS_00517	A0A151GPQ6	A0A151GQJ8	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	WD repeat containing protein 36.	0.755
DCS_00203	DCS_00518	A0A151GPQ6	A0A151GQP6	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.578
DCS_00203	DCS_00555	A0A151GPQ6	A0A151GQN4	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.915
DCS_00203	DCS_00577	A0A151GPQ6	A0A151GQR1	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Ribosome biogenesis protein.	0.890
DCS_00203	DCS_00771	A0A151GPQ6	A0A151GRE6	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.731
DCS_00203	DCS_00871	A0A151GPQ6	A0A151GRJ2	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Importin N-terminal domain-containing protein.	0.596
DCS_00203	DCS_00968	A0A151GPQ6	A0A151GRT4	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Sas10/Utp3/C1D family protein.	0.539
DCS_00203	DCS_00978	A0A151GPQ6	A0A151GRU3	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	RRM domain-containing protein.	0.489
DCS_00203	DCS_01018	A0A151GPQ6	A0A151GRZ8	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.504
DCS_00203	DCS_01116	A0A151GPQ6	A0A151GSI8	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Protein phosphatase; Belongs to the PP2C family.	0.470
DCS_00203	DCS_01130	A0A151GPQ6	A0A151GSA5	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.549
DCS_00203	DCS_01166	A0A151GPQ6	A0A151GSN4	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.417
DCS_00203	DCS_01221	A0A151GPQ6	A0A151GSL1	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	U3 small nucleolar RNA-associated protein.	0.829
DCS_00203	DCS_01280	A0A151GPQ6	A0A151GSR4	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.907