(48 nodes) Preribosome, large subunit precursor, and DEAD/DEAH box helicase domain network (Drechmeria coniospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCS_06186	Brix domain-containing protein 2. (540 aa)
	DCS_06256	Eukaryotic rRNA processing. (402 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (836 aa)
	DCS_06395	Nucleolar protein NOP52 variant. (262 aa)
	DCS_06409	Putative DEAD box protein; Belongs to the DEAD box helicase family. (488 aa)
	DCS_06641	ATP-dependent RNA helicase ROK1. (757 aa)
	DCS_07281	RNA helicase. (629 aa)
	DCS_07408	Nucleolar GTP-binding protein 2. (550 aa)
	DCS_07420	Brix domain-containing protein. (320 aa)
	DCS_07463	Pumilio domain-containing protein. (691 aa)
	DCS_07456	Ribosome biogenesis protein NSA2. (260 aa)
	DCS_07737	tRNA-methyltransferase NCL1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (679 aa)
	DCS_07791	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (670 aa)
	DCS_07790	Brix domain containing protein. (412 aa)
	DCS_07922	CCAAT-box-binding transcription factor. (971 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (749 aa)
	DCS_08023	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (588 aa)
	DCS_08167	ATP-dependent RNA helicase DOB1. (1103 aa)
	DCS_03424	Dependent RNA helicase drs-1; Belongs to the DEAD box helicase family. (786 aa)
	DCS_03458	Uncharacterized protein. (165 aa)
	DCS_03575	WD_REPEATS_REGION domain-containing protein. (1120 aa)
	DCS_03605	ATP-dependent RNA helicase dbp9. (620 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (647 aa)
	DCS_03897	Nucleolar protein 12. (539 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (474 aa)
	DCS_04353	ATP-dependent RNA helicase dbp3; Belongs to the DEAD box helicase family. (596 aa)
	DCS_04373	rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (120 aa)
	DCS_04549	Ribosome assembly protein Noc2. (778 aa)
	DCS_04824	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (188 aa)
	DCS_05114	RNA helicase. (576 aa)
	DCS_05225	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (197 aa)
	DCS_05427	RRM domain-containing protein. (367 aa)
	DCS_00203	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family. (570 aa)
	DCS_00399	Uncharacterized protein. (418 aa)
	DCS_00427	ATP-dependent RNA helicase mss116; Belongs to the DEAD box helicase family. (653 aa)
	DCS_00451	ATP-dependent RNA helicase DBP7; Belongs to the DEAD box helicase family. (742 aa)
	DCS_00555	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (653 aa)
	DCS_00518	Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (850 aa)
	DCS_01130	Uncharacterized protein. (474 aa)
	DCS_01280	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (247 aa)
	DCS_02252	Uncharacterized protein. (802 aa)
	DCS_02451	Electron transfer flavoprotein alpha-subunit. (381 aa)
	DCS_02635	Uncharacterized protein. (205 aa)
	DCS_02744	Nucleolar protein 16. (238 aa)
	DCS_02792	Protein MAK16; Belongs to the MAK16 family. (309 aa)
	DCS_02891	Ribosomal RNA-processing protein 12. (1257 aa)
	DCS_03022	RNA recognition motif containing protein. (721 aa)
	DCS_03124	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (455 aa)

Your Current Organism:

Drechmeria coniospora

NCBI taxonomy Id: 98403
Other names: CBS 615.82, D. coniospora, Meria coniospora

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCS_00203	DCS_00399	A0A151GPQ6	A0A151GQ86	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.798
DCS_00203	DCS_00451	A0A151GPQ6	A0A151GQI5	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	ATP-dependent RNA helicase DBP7; Belongs to the DEAD box helicase family.	0.667
DCS_00203	DCS_00518	A0A151GPQ6	A0A151GQP6	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.578
DCS_00203	DCS_00555	A0A151GPQ6	A0A151GQN4	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.915
DCS_00203	DCS_01130	A0A151GPQ6	A0A151GSA5	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.549
DCS_00203	DCS_01280	A0A151GPQ6	A0A151GSR4	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.907
DCS_00203	DCS_02252	A0A151GPQ6	A0A151GVL0	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.826
DCS_00203	DCS_02451	A0A151GPQ6	A0A151GW29	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Electron transfer flavoprotein alpha-subunit.	0.908
DCS_00203	DCS_02635	A0A151GPQ6	A0A151GWS1	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.661
DCS_00203	DCS_02744	A0A151GPQ6	A0A151GX06	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Nucleolar protein 16.	0.853
DCS_00203	DCS_02792	A0A151GPQ6	A0A151GX15	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Protein MAK16; Belongs to the MAK16 family.	0.883
DCS_00203	DCS_02891	A0A151GPQ6	A0A151GXC2	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Ribosomal RNA-processing protein 12.	0.698
DCS_00203	DCS_03022	A0A151GPQ6	A0A151GXQ0	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	RNA recognition motif containing protein.	0.762
DCS_00203	DCS_03124	A0A151GPQ6	A0A151GXY9	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.	0.426
DCS_00203	DCS_03424	A0A151GPQ6	A0A151GH69	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Dependent RNA helicase drs-1; Belongs to the DEAD box helicase family.	0.686
DCS_00203	DCS_03458	A0A151GPQ6	A0A151GHA8	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.426
DCS_00203	DCS_03575	A0A151GPQ6	A0A151GHJ6	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	WD_REPEATS_REGION domain-containing protein.	0.676
DCS_00203	DCS_03605	A0A151GPQ6	A0A151GHM6	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	ATP-dependent RNA helicase dbp9.	0.733
DCS_00203	DCS_03897	A0A151GPQ6	A0A151GIL8	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	Nucleolar protein 12.	0.665
DCS_00203	DCS_04353	A0A151GPQ6	A0A151GJR4	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family.	ATP-dependent RNA helicase dbp3; Belongs to the DEAD box helicase family.	0.527