(16 nodes) Dynactin complex, and F-actin capping protein complex network (Drechmeria coniospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCS_06621	Uncharacterized protein. (289 aa)
	DCS_06920	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (289 aa)
	DCS_06988	Uncharacterized protein. (644 aa)
	DCS_07366	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (311 aa)
	DCS_07755	Putative dynactin ro-3. (1346 aa)
	DCS_07988	Dynactin subunit. (412 aa)
	DCS_03347	Nuclear distribution protein nudE. (728 aa)
	DCS_03486	Dynactin subunit. (557 aa)
	DCS_03461	Putative l-amino acid oxidase protein. (624 aa)
	DCS_03745	RRN9 domain-containing protein. (680 aa)
	DCS_04317	Nuclear movement protein nudC. (189 aa)
	DCS_05409	Actin-protein RO7; Belongs to the actin family. (571 aa)
	DCS_00661	Dynein heavy chain, cytoplasmic. (4369 aa)
	DCS_01656	Uncharacterized protein. (198 aa)
	DCS_01778	Transferase hexapeptide domain protein. (194 aa)
	PAC1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (452 aa)

Your Current Organism:

Drechmeria coniospora

NCBI taxonomy Id: 98403
Other names: CBS 615.82, D. coniospora, Meria coniospora

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCS_00661	DCS_01656	A0A151GR50	A0A151GTS9	Dynein heavy chain, cytoplasmic.	Uncharacterized protein.	0.806
DCS_00661	DCS_01778	A0A151GR50	A0A151GU86	Dynein heavy chain, cytoplasmic.	Transferase hexapeptide domain protein.	0.820
DCS_00661	DCS_03347	A0A151GR50	A0A151GGW2	Dynein heavy chain, cytoplasmic.	Nuclear distribution protein nudE.	0.628
DCS_00661	DCS_03461	A0A151GR50	A0A151GHD5	Dynein heavy chain, cytoplasmic.	Putative l-amino acid oxidase protein.	0.967
DCS_00661	DCS_03486	A0A151GR50	A0A151GHC5	Dynein heavy chain, cytoplasmic.	Dynactin subunit.	0.838
DCS_00661	DCS_03745	A0A151GR50	A0A151GI42	Dynein heavy chain, cytoplasmic.	RRN9 domain-containing protein.	0.742
DCS_00661	DCS_04317	A0A151GR50	A0A151GJP5	Dynein heavy chain, cytoplasmic.	Nuclear movement protein nudC.	0.735
DCS_00661	DCS_05409	A0A151GR50	A0A151GMQ9	Dynein heavy chain, cytoplasmic.	Actin-protein RO7; Belongs to the actin family.	0.814
DCS_00661	DCS_06621	A0A151GR50	A0A151GC80	Dynein heavy chain, cytoplasmic.	Uncharacterized protein.	0.742
DCS_00661	DCS_06920	A0A151GR50	A0A151GCY1	Dynein heavy chain, cytoplasmic.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.742
DCS_00661	DCS_06988	A0A151GR50	A0A151GD51	Dynein heavy chain, cytoplasmic.	Uncharacterized protein.	0.742
DCS_00661	DCS_07366	A0A151GR50	A0A151GEA1	Dynein heavy chain, cytoplasmic.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.838
DCS_00661	DCS_07755	A0A151GR50	A0A151GFG4	Dynein heavy chain, cytoplasmic.	Putative dynactin ro-3.	0.978
DCS_00661	DCS_07988	A0A151GR50	A0A151GG26	Dynein heavy chain, cytoplasmic.	Dynactin subunit.	0.960
DCS_00661	PAC1	A0A151GR50	A0A151GW27	Dynein heavy chain, cytoplasmic.	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	0.994
DCS_01656	DCS_00661	A0A151GTS9	A0A151GR50	Uncharacterized protein.	Dynein heavy chain, cytoplasmic.	0.806
DCS_01656	DCS_01778	A0A151GTS9	A0A151GU86	Uncharacterized protein.	Transferase hexapeptide domain protein.	0.993
DCS_01656	DCS_03461	A0A151GTS9	A0A151GHD5	Uncharacterized protein.	Putative l-amino acid oxidase protein.	0.617
DCS_01656	DCS_03486	A0A151GTS9	A0A151GHC5	Uncharacterized protein.	Dynactin subunit.	0.996
DCS_01656	DCS_03745	A0A151GTS9	A0A151GI42	Uncharacterized protein.	RRN9 domain-containing protein.	0.811