(93 nodes) Actin cytoskeleton organization network (Drechmeria coniospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCS_07077	Uncharacterized protein. (602 aa)
	DCS_06992	Drf_GBD domain-containing protein. (826 aa)
	DCS_07006	SH3 domain-containing protein. (395 aa)
	DCS_07070	Uncharacterized protein. (293 aa)
	DCS_07114	Cell division control protein. (896 aa)
	DCS_07126	Epsin-like protein ent1 2. (564 aa)
	DCS_07323	Small GTPase superfamily. (215 aa)
	DCS_07341	RPEL repeat protein. (127 aa)
	DCS_07366	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (311 aa)
	DCS_07391	Uncharacterized protein. (1162 aa)
	DCS_07406	Serine/threonine-protein kinase domain protein. (645 aa)
	DCS_07654	Ras family protein. (274 aa)
	DCS_07663	Uncharacterized protein. (284 aa)
	DCS_07734	Cofilin; Belongs to the actin-binding proteins ADF family. (206 aa)
	DCS_07805	Cell division control protein 42. (195 aa)
	DCS_07931	LIM domain protein. (756 aa)
	DCS_08052	Fungal hydrophobin. (135 aa)
	DCS_08077	WD_REPEATS_REGION domain-containing protein. (621 aa)
	DCS_08156	Tyrosine phosphatase. (302 aa)
	DCS_08128	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (191 aa)
	DCS_08179	Uncharacterized protein. (375 aa)
	DCS_03489	Twinfilin. (332 aa)
	DCS_03700	Myosin-5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1122 aa)
	DCS_03651	SH3 domain containing protein. (959 aa)
	DCS_03678	PH domain containing protein. (397 aa)
	DCS_03661	Cytosolic regulator Pianissimo. (1407 aa)
	DCS_03783	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (202 aa)
	DCS_03860	Putative arp2 3 complex 34 kDa subunit protein. (590 aa)
	DCS_03941	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
	DCS_03969	Serine/threonine protein kinase. (1001 aa)
	DCS_04037	Actin-related protein 2/3 complex subunit 4. (305 aa)
	DCS_04087	Hydrophobin. (95 aa)
	DCS_04038	Uncharacterized protein. (313 aa)
	DCS_04039	Uncharacterized protein. (533 aa)
	DCS_04168	Hob3. (261 aa)
	DCS_04352	Uncharacterized protein. (296 aa)
	DCS_04468	Putative golgi to endosome transport protein. (528 aa)
	DCS_04615	Putative Cutinase transcription factor 1 alpha. (778 aa)
	DCS_04687	TYR_PHOSPHATASE_2 domain-containing protein. (726 aa)
	DCS_04894	Myosin type II heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2358 aa)
	DCS_04895	Uncharacterized protein. (187 aa)
	DCS_05067	Putative fimbrin. (647 aa)
	DCS_05098	Arad-like aldolase/epimerase. (314 aa)
	DCS_05186	Uncharacterized protein. (902 aa)
	DCS_05418	Putative GTPase Rho. (195 aa)
	DCS_05431	Putative actin-interacting protein AIP3. (1020 aa)
	DCS_05616	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	DCS_05666	Vacuolar sorting protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (722 aa)
	DCS_05685	Actin. (501 aa)
	DCS_05763	Uncharacterized protein. (300 aa)
	DCS_05798	Uncharacterized protein. (110 aa)
	DCS_00063	Uncharacterized protein. (209 aa)
	DCS_00224	Uncharacterized protein. (198 aa)
	DCS_00371	Uncharacterized protein. (222 aa)
	DCS_00476	Putative SAGA protein. (419 aa)
	DCS_00610	Profilin; Belongs to the profilin family. (127 aa)
	DCS_00843	Adenylyl cyclase-associated protein; Belongs to the CAP family. (520 aa)
	DCS_00919	WH1 domain-containing protein. (681 aa)
	DCS_00886	Uncharacterized protein. (1050 aa)
	DCS_01203	Uncharacterized protein. (885 aa)
	DCS_01182	Coronin; Belongs to the WD repeat coronin family. (607 aa)
	DCS_01262	Uncharacterized protein. (758 aa)
	DCS_01356	ADP-ribosylation factor. (1396 aa)
	DCS_01315	Uncharacterized protein. (283 aa)
	DCS_01376	Uncharacterized protein. (564 aa)
	DCS_01375	Glycosyl transferase. (333 aa)
	DCS_01516	WD_REPEATS_REGION domain-containing protein. (612 aa)
	DCS_01711	Uncharacterized protein. (393 aa)
	DCS_01731	Actin polymerization protein Bzz1. (742 aa)
	DCS_01848	DUF2013 domain-containing protein. (512 aa)
	DCS_02104	Putative BAR adaptor protein. (427 aa)
	DCS_02109	WD-repeat protein pop3. (480 aa)
	DCS_02277	F-box domain-containing protein. (284 aa)
	DCS_02436	Fes/CIP4 domain-containing protein. (860 aa)
	DCS_02543	SH3 domain-containing protein. (1204 aa)
	DCS_02774	Rho GTPase effector BNI1. (1682 aa)
	DCS_02978	Rho GTPase. (615 aa)
	DCS_03016	Uncharacterized protein. (809 aa)
	DCS_03193	Uncharacterized protein. (395 aa)
	DCS_03271	Glycosyl transferase. (409 aa)
	DCS_08300	SH3 domain-containing protein. (670 aa)
	DCS_05979	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (427 aa)
	DCS_06065	ANK_REP_REGION domain-containing protein. (264 aa)
	DCS_06156	Actin-like protein 3; Belongs to the actin family. (442 aa)
	DCS_06193	Uncharacterized protein. (2374 aa)
	DCS_06271	Actin lateral binding protein. (161 aa)
	DCS_06397	GTPase activating protein. (1451 aa)
	DCS_06425	C6 transcription factor. (637 aa)
	DCS_06440	Ras-related GTPase, Rho2 subfamily. (198 aa)
	DCS_06482	Uncharacterized protein. (1104 aa)
	DCS_06731	Uncharacterized protein. (281 aa)
	DCS_06916	VHS domain protein. (421 aa)
	DCS_06988	Uncharacterized protein. (644 aa)

Your Current Organism:

Drechmeria coniospora

NCBI taxonomy Id: 98403
Other names: CBS 615.82, D. coniospora, Meria coniospora

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCS_00063	DCS_00224	A0A151GPB8	A0A151GPS4	Uncharacterized protein.	Uncharacterized protein.	0.906
DCS_00063	DCS_00371	A0A151GPB8	A0A151GQA8	Uncharacterized protein.	Uncharacterized protein.	0.672
DCS_00063	DCS_00610	A0A151GPB8	A0A151GQW7	Uncharacterized protein.	Profilin; Belongs to the profilin family.	0.699
DCS_00063	DCS_00886	A0A151GPB8	A0A151GRW8	Uncharacterized protein.	Uncharacterized protein.	0.466
DCS_00063	DCS_00919	A0A151GPB8	A0A151GRP9	Uncharacterized protein.	WH1 domain-containing protein.	0.765
DCS_00063	DCS_01203	A0A151GPB8	A0A151GSI5	Uncharacterized protein.	Uncharacterized protein.	0.617
DCS_00063	DCS_01262	A0A151GPB8	A0A151GSQ2	Uncharacterized protein.	Uncharacterized protein.	0.563
DCS_00063	DCS_01315	A0A151GPB8	A0A151GSY2	Uncharacterized protein.	Uncharacterized protein.	0.739
DCS_00063	DCS_01375	A0A151GPB8	A0A151GT33	Uncharacterized protein.	Glycosyl transferase.	0.713
DCS_00063	DCS_01376	A0A151GPB8	A0A151GSZ4	Uncharacterized protein.	Uncharacterized protein.	0.633
DCS_00063	DCS_01731	A0A151GPB8	A0A151GTZ5	Uncharacterized protein.	Actin polymerization protein Bzz1.	0.693
DCS_00063	DCS_01848	A0A151GPB8	A0A151GUF5	Uncharacterized protein.	DUF2013 domain-containing protein.	0.574
DCS_00063	DCS_02109	A0A151GPB8	A0A151GV42	Uncharacterized protein.	WD-repeat protein pop3.	0.602
DCS_00063	DCS_02774	A0A151GPB8	A0A151GX37	Uncharacterized protein.	Rho GTPase effector BNI1.	0.751
DCS_00063	DCS_02978	A0A151GPB8	A0A151GXK4	Uncharacterized protein.	Rho GTPase.	0.629
DCS_00063	DCS_03016	A0A151GPB8	A0A151GXU7	Uncharacterized protein.	Uncharacterized protein.	0.617
DCS_00063	DCS_03271	A0A151GPB8	A0A151GYF1	Uncharacterized protein.	Glycosyl transferase.	0.713
DCS_00063	DCS_03489	A0A151GPB8	A0A151GHE4	Uncharacterized protein.	Twinfilin.	0.597
DCS_00063	DCS_03678	A0A151GPB8	A0A151GHV8	Uncharacterized protein.	PH domain containing protein.	0.571
DCS_00063	DCS_03783	A0A151GPB8	A0A151GI47	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.594