(33 nodes) Cortical actin cytoskeleton organization network (Drechmeria coniospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCS_00610	Profilin; Belongs to the profilin family. (127 aa)
	DCS_08300	SH3 domain-containing protein. (670 aa)
	DCS_05979	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (427 aa)
	DCS_06156	Actin-like protein 3; Belongs to the actin family. (442 aa)
	DCS_06271	Actin lateral binding protein. (161 aa)
	DCS_04037	Actin-related protein 2/3 complex subunit 4. (305 aa)
	DCS_04038	Uncharacterized protein. (313 aa)
	DCS_04039	Uncharacterized protein. (533 aa)
	DCS_04352	Uncharacterized protein. (296 aa)
	DCS_04687	TYR_PHOSPHATASE_2 domain-containing protein. (726 aa)
	DCS_04894	Myosin type II heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2358 aa)
	DCS_07931	LIM domain protein. (756 aa)
	DCS_07663	Uncharacterized protein. (284 aa)
	DCS_07654	Ras family protein. (274 aa)
	DCS_07114	Cell division control protein. (896 aa)
	DCS_06482	Uncharacterized protein. (1104 aa)
	DCS_05616	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	DCS_05685	Actin. (501 aa)
	DCS_00371	Uncharacterized protein. (222 aa)
	DCS_00886	Uncharacterized protein. (1050 aa)
	DCS_01203	Uncharacterized protein. (885 aa)
	DCS_03969	Serine/threonine protein kinase. (1001 aa)
	DCS_03941	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
	DCS_03860	Putative arp2 3 complex 34 kDa subunit protein. (590 aa)
	DCS_03783	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (202 aa)
	DCS_03678	PH domain containing protein. (397 aa)
	DCS_03700	Myosin-5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1122 aa)
	DCS_08128	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (191 aa)
	DCS_01848	DUF2013 domain-containing protein. (512 aa)
	DCS_02104	Putative BAR adaptor protein. (427 aa)
	DCS_02436	Fes/CIP4 domain-containing protein. (860 aa)
	DCS_02774	Rho GTPase effector BNI1. (1682 aa)
	DCS_03016	Uncharacterized protein. (809 aa)

Your Current Organism:

Drechmeria coniospora

NCBI taxonomy Id: 98403
Other names: CBS 615.82, D. coniospora, Meria coniospora

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCS_00371	DCS_01203	A0A151GQA8	A0A151GSI5	Uncharacterized protein.	Uncharacterized protein.	0.703
DCS_00371	DCS_02774	A0A151GQA8	A0A151GX37	Uncharacterized protein.	Rho GTPase effector BNI1.	0.495
DCS_00371	DCS_03016	A0A151GQA8	A0A151GXU7	Uncharacterized protein.	Uncharacterized protein.	0.703
DCS_00371	DCS_03678	A0A151GQA8	A0A151GHV8	Uncharacterized protein.	PH domain containing protein.	0.596
DCS_00371	DCS_03700	A0A151GQA8	A0A151GHV3	Uncharacterized protein.	Myosin-5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.801
DCS_00371	DCS_04352	A0A151GQA8	A0A151GJN6	Uncharacterized protein.	Uncharacterized protein.	0.439
DCS_00371	DCS_04687	A0A151GQA8	A0A151GKN7	Uncharacterized protein.	TYR_PHOSPHATASE_2 domain-containing protein.	0.456
DCS_00371	DCS_04894	A0A151GQA8	A0A151GLH6	Uncharacterized protein.	Myosin type II heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.975
DCS_00371	DCS_05685	A0A151GQA8	A0A151GNM4	Uncharacterized protein.	Actin.	0.777
DCS_00371	DCS_05979	A0A151GQA8	A0A151GAB8	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.549
DCS_00371	DCS_06156	A0A151GQA8	A0A151GAS9	Uncharacterized protein.	Actin-like protein 3; Belongs to the actin family.	0.613
DCS_00371	DCS_06271	A0A151GQA8	A0A151GB89	Uncharacterized protein.	Actin lateral binding protein.	0.839
DCS_00371	DCS_07114	A0A151GQA8	A0A151GDG8	Uncharacterized protein.	Cell division control protein.	0.624
DCS_00371	DCS_07654	A0A151GQA8	A0A151GF14	Uncharacterized protein.	Ras family protein.	0.672
DCS_00371	DCS_07663	A0A151GQA8	A0A151GF30	Uncharacterized protein.	Uncharacterized protein.	0.495
DCS_00371	DCS_07931	A0A151GQA8	A0A151GFX3	Uncharacterized protein.	LIM domain protein.	0.668
DCS_00610	DCS_02774	A0A151GQW7	A0A151GX37	Profilin; Belongs to the profilin family.	Rho GTPase effector BNI1.	0.842
DCS_00610	DCS_03678	A0A151GQW7	A0A151GHV8	Profilin; Belongs to the profilin family.	PH domain containing protein.	0.426
DCS_00610	DCS_03941	A0A151GQW7	A0A151GII8	Profilin; Belongs to the profilin family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.435
DCS_00610	DCS_04352	A0A151GQW7	A0A151GJN6	Profilin; Belongs to the profilin family.	Uncharacterized protein.	0.835