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prpE prpE SGRA_0746 SGRA_0746 SGRA_1245 SGRA_1245 SGRA_1892 SGRA_1892 SGRA_1893 SGRA_1893 SGRA_1894 SGRA_1894 SGRA_2469 SGRA_2469 SGRA_2632 SGRA_2632 SGRA_2823 SGRA_2823 acs acs
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prpEprpE protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (627 aa)
SGRA_0746Putative zinc-type alcohol dehydrogenase-like protein; COG1064 Zn-dependent alcohol dehydrogenases. (335 aa)
SGRA_1245Alcohol dehydrogenase zinc-binding domain protein; COG1064 Zn-dependent alcohol dehydrogenases. (350 aa)
SGRA_1892COG2207 AraC-type DNA-binding domain-containing proteins. (296 aa)
SGRA_1893COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (506 aa)
SGRA_1894COG3564 Uncharacterized protein conserved in bacteria. (119 aa)
SGRA_2469COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (517 aa)
SGRA_2632COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (471 aa)
SGRA_2823COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (553 aa)
acsAcetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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