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SGRA_1449 SGRA_1449 thiC thiC SGRA_1451 SGRA_1451 thiE thiE thiD thiD thiE-2 thiE-2 thiG thiG SGRA_1456 SGRA_1456 thiH thiH SGRA_2019 SGRA_2019 SGRA_2020 SGRA_2020 SGRA_2021 SGRA_2021 SGRA_2022 SGRA_2022 SGRA_2023 SGRA_2023 SGRA_2318 SGRA_2318 SGRA_2319 SGRA_2319 SGRA_2997 SGRA_2997
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGRA_1449COG2104 Sulfur transfer protein involved in thiamine biosynthesis. (90 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (623 aa)
SGRA_1451Hypothetical protein. (67 aa)
thiEThiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase. (218 aa)
thiDCOG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (253 aa)
thiE-2Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (218 aa)
thiGThiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (256 aa)
SGRA_1456Hypothetical protein. (106 aa)
thiHCOG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (381 aa)
SGRA_2019UBA/THIF-type NAD/FAD binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (383 aa)
SGRA_2020Thiamine S protein; COG1977 Molybdopterin converting factor, small subunit. (93 aa)
SGRA_2021Mov34/MPN/PAD-1 family protein; COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily. (155 aa)
SGRA_2022COG0031 Cysteine synthase. (313 aa)
SGRA_2023Hypothetical protein. (38 aa)
SGRA_2318Galanin. (302 aa)
SGRA_2319Putative manganese transporter; COG1914 Mn2+ and Fe2+ transporters of the NRAMP family. (405 aa)
SGRA_2997Galanin. (331 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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