Your Input: | |
| | fbaB | COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes. (350 aa) |
| | scoA | COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (231 aa) |
| | scoB | COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit. (219 aa) |
| | atoB | acetoacetyl-CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa) |
| | pccB | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (501 aa) |
| | rpiB | COG0698 Ribose 5-phosphate isomerase RpiB. (149 aa) |
| | fabD | COG0331 (acyl-carrier-protein) S-malonyltransferase. (293 aa) |
| | SGRA_0550 | COG0436 Aspartate/tyrosine/aromatic aminotransferase. (373 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa) |
| | gloA | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. (133 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa) |
| | prpE | prpE protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (627 aa) |
| | icd | COG0473 Isocitrate/isopropylmalate dehydrogenase. (481 aa) |
| | lpd | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (472 aa) |
| | SGRA_0746 | Putative zinc-type alcohol dehydrogenase-like protein; COG1064 Zn-dependent alcohol dehydrogenases. (335 aa) |
| | atoB-2 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa) |
| | SGRA_0820 | COG0724 RNA-binding proteins (RRM domain). (122 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (374 aa) |
| | fbp | COG0158 Fructose-1,6-bisphosphatase. (327 aa) |
| | gapA | COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (495 aa) |
| | crt | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa) |
| | SGRA_1245 | Alcohol dehydrogenase zinc-binding domain protein; COG1064 Zn-dependent alcohol dehydrogenases. (350 aa) |
| | SGRA_1247 | Phosphoglycerate mutase family protein; COG0406 Fructose-2,6-bisphosphatase. (170 aa) |
| | talA | Putative translaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (335 aa) |
| | birA | COG0340 Biotin-(acetyl-CoA carboxylase) ligase. (272 aa) |
| | SGRA_1401 | Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (427 aa) |
| | fabZ | (3R)-hydroxymyristoyl-[acyl-carrier- protein]dehydratase; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases. (153 aa) |
| | fabI | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (261 aa) |
| | bcsA | Chalcone and stilbene synthase domain protein; COG3424 Predicted naringenin-chalcone synthase. (352 aa) |
| | pcaF | Beta-ketoadipyl CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (320 aa) |
| | fumC | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | fadD | COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (607 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa) |
| | SGRA_1806 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (713 aa) |
| | sucA | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (922 aa) |
| | SGRA_1892 | COG2207 AraC-type DNA-binding domain-containing proteins. (296 aa) |
| | SGRA_1893 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | SGRA_1894 | COG3564 Uncharacterized protein conserved in bacteria. (119 aa) |
| | icmF | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1119 aa) |
| | SGRA_1936 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (665 aa) |
| | pfk | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa) |
| | tktA | COG3959 Transketolase, N-terminal subunit. (281 aa) |
| | tktA-2 | COG3958 Transketolase, C-terminal subunit. (317 aa) |
| | SGRA_2079 | Hypothetical protein. (74 aa) |
| | SGRA_2080 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (233 aa) |
| | fabI-2 | COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH). (294 aa) |
| | SGRA_2222 | WD-40 repeat protein; COG2319 FOG: WD40 repeat. (625 aa) |
| | SGRA_2223 | COG1960 Acyl-CoA dehydrogenases. (598 aa) |
| | sdhC | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (207 aa) |
| | sdhA | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (667 aa) |
| | sdhB | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (257 aa) |
| | SGRA_2313 | Transketolase domain protein; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (803 aa) |
| | gltA | COG0372 Citrate synthase; Belongs to the citrate synthase family. (440 aa) |
| | SGRA_2469 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (517 aa) |
| | fadN | COG1250 3-hydroxyacyl-CoA dehydrogenase. (787 aa) |
| | fadA | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa) |
| | fabF | 3-oxoacyl-(acyl-carrier-protein) synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (416 aa) |
| | fadJ | 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (704 aa) |
| | pyk | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa) |
| | pdhB | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa) |
| | SGRA_2576 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (361 aa) |
| | SGRA_2632 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (471 aa) |
| | accB | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (171 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa) |
| | argK | Arginine/ornithine transport system ATPase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family. (360 aa) |
| | sucB | 2-oxoglutarate dehydrogenase, e2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (420 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (352 aa) |
| | icd-2 | COG0538 Isocitrate dehydrogenases. (399 aa) |
| | SGRA_2823 | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (553 aa) |
| | pccB-2 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (541 aa) |
| | paaH | COG1250 3-hydroxyacyl-CoA dehydrogenase. (296 aa) |
| | fabG | 3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (233 aa) |
| | SGRA_2923 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (473 aa) |
| | hmgL | hydroxymethylglutaryl-CoA lyase; COG0119 Isopropylmalate/homocitrate/citramalate synthases. (276 aa) |
| | fadD-2 | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (568 aa) |
| | fabH-2 | COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III. (358 aa) |
| | gcdH | COG1960 Acyl-CoA dehydrogenases. (405 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (257 aa) |
| | SGRA_3003 | COG1960 Acyl-CoA dehydrogenases. (599 aa) |
| | aceF | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (417 aa) |
| | fixB | COG2025 Electron transfer flavoprotein, alpha subunit. (319 aa) |
| | fixA | COG2086 Electron transfer flavoprotein, beta subunit. (212 aa) |
| | SGRA_3157 | Lipase family protein; COG3675 Predicted lipase. (422 aa) |
| | mtnU | Putative NAD(P)-binding amidase-type enzyme with nitrilase/N-carbamoyl-D-aminoacid amidohydrolase; COG0388 Predicted amidohydrolase. (253 aa) |
| | gpm | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | manA | Bifunctional phosphoglucose/phosphomannose isomerase; COG0166 Glucose-6-phosphate isomerase. (330 aa) |
| | SGRA_3390 | Methyltransferase type 12; COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase. (235 aa) |
| | SGRA_3391 | Monooxygenase FAD-binding protein; COG0644 Dehydrogenases (flavoproteins). (388 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (695 aa) |
| | acs | Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa) |
| | rpe | COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa) |
| | SGRA_3529 | COG1960 Acyl-CoA dehydrogenases. (388 aa) |
| | fabG-2 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa) |
| | acnA | Aconitate hydratase; COG1048 Aconitase A. (759 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (405 aa) |
| | sucB-2 | Catalytic domain of components of various dehydrogenase complexes; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (441 aa) |
| | aspB | Aminotransferase class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (399 aa) |
| | SGRA_3772 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (497 aa) |
| | sfcA | Malate dehydrogenase; COG0281 Malic enzyme. (403 aa) |
| | SGRA_3861 | NADP-dependent L-serine/L-allo-threonine dehydrogenase; COG4221 Short-chain alcohol dehydrogenase of unknown specificity. (737 aa) |
| | pgk | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa) |
| | gapA-2 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | SGRA_4028 | COG1960 Acyl-CoA dehydrogenases. (613 aa) |
| | lpd-2 | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (470 aa) |
