STRINGSTRING
SGRA_4085 SGRA_4085 SGRA_4084 SGRA_4084 SGRA_4080 SGRA_4080 hemF hemF SGRA_3827 SGRA_3827 mreC mreC clpX clpX SGRA_3304 SGRA_3304 SGRA_3292 SGRA_3292 SGRA_3279 SGRA_3279 SGRA_3138 SGRA_3138 troR troR SGRA_2786 SGRA_2786 asd asd SGRA_2536 SGRA_2536 SGRA_2472 SGRA_2472 greA greA SGRA_2052 SGRA_2052 SGRA_2008 SGRA_2008 rpoA rpoA SGRA_1796 SGRA_1796 SGRA_1770 SGRA_1770 clpS clpS hscB hscB SGRA_1270 SGRA_1270 djlA djlA dnaK dnaK grpE grpE dnaJ dnaJ htpG htpG hscA hscA pilQ pilQ SGRA_0673 SGRA_0673 pspA pspA hlpA-2 hlpA-2 hlpA hlpA SGRA_0503 SGRA_0503 groEL groEL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGRA_4085Hypothetical protein. (181 aa)
SGRA_4084COG0576 Molecular chaperone GrpE (heat shock protein). (151 aa)
SGRA_4080Heat shock protein Hsp70; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. (752 aa)
hemFCOG0408 Coproporphyrinogen III oxidase. (308 aa)
SGRA_3827Hypothetical protein. (120 aa)
mreCCOG1792 Cell shape-determining protein. (281 aa)
clpXSigma 54 interacting domain protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (419 aa)
SGRA_3304Hypothetical protein; COG1077 Actin-like ATPase involved in cell morphogenesis. (1163 aa)
SGRA_3292Band 7 protein; COG2268 Uncharacterized protein conserved in bacteria. (710 aa)
SGRA_3279Hypothetical protein. (146 aa)
SGRA_3138Hypothetical protein. (509 aa)
troRIron dependent repressor; COG1321 Mn-dependent transcriptional regulator. (223 aa)
SGRA_2786Hypothetical protein. (99 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa)
SGRA_2536COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family. (136 aa)
SGRA_2472Hypothetical protein. (173 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (160 aa)
SGRA_2052COG1952 Preprotein translocase subunit SecB. (125 aa)
SGRA_2008Putative septum formation initiator-related protein. (109 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa)
SGRA_1796COG1952 Preprotein translocase subunit SecB. (145 aa)
SGRA_1770General stress protein; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). (130 aa)
clpSATP-dependent Clp protease adaptor protein ClpS; Belongs to the ClpS family. (101 aa)
hscBCo-chaperone Hsc20; COG1076 DnaJ-domain-containing proteins 1. (176 aa)
SGRA_1270Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. (148 aa)
djlACOG1076 DnaJ-domain-containing proteins 1. (252 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (616 aa)
grpEGrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] (185 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (392 aa)
htpGATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity. (619 aa)
hscAFe-S protein assembly chaperone HscA; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. (629 aa)
pilQType II and III secretion system protein; COG4796 Type II secretory pathway, component HofQ; Belongs to the bacterial secretin family. (664 aa)
SGRA_0673Outer membrane chaperone Skp (OmpH); COG2825 Outer membrane protein. (168 aa)
pspApspA/IM30 family protein; COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription. (262 aa)
hlpA-2Outer membrane chaperone Skp (OmpH); COG2825 Outer membrane protein. (155 aa)
hlpAOuter membrane chaperone Skp (OmpH); COG2825 Outer membrane protein. (171 aa)
SGRA_0503Outer membrane chaperone Skp (OmpH); COG2825 Outer membrane protein. (168 aa)
groELChaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (546 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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