STRINGSTRING
rpoE-4 rpoE-4 nusA nusA SGRA_1132 SGRA_1132 SGRA_1158 SGRA_1158 SGRA_1244 SGRA_1244 SGRA_1246 SGRA_1246 SGRA_1250 SGRA_1250 SGRA_1255 SGRA_1255 pleC1 pleC1 SGRA_0043 SGRA_0043 SGRA_0128 SGRA_0128 SGRA_0144 SGRA_0144 SGRA_0197 SGRA_0197 phoB1 phoB1 SGRA_0310 SGRA_0310 SGRA_0410 SGRA_0410 SGRA_0451 SGRA_0451 SGRA_0518 SGRA_0518 SGRA_0546 SGRA_0546 SGRA_0571 SGRA_0571 SGRA_0576 SGRA_0576 degS degS narL narL rpoE rpoE SGRA_0626 SGRA_0626 fur fur SGRA_0696 SGRA_0696 SGRA_0705 SGRA_0705 rpoE-2 rpoE-2 SGRA_0735 SGRA_0735 SGRA_0764 SGRA_0764 rpoD rpoD SGRA_0789 SGRA_0789 mraZ mraZ SGRA_1024 SGRA_1024 rpoE-3 rpoE-3 hupB hupB SGRA_1293 SGRA_1293 birA birA SGRA_1375 SGRA_1375 SGRA_1410 SGRA_1410 SGRA_1412 SGRA_1412 SGRA_1467 SGRA_1467 SGRA_1541 SGRA_1541 SGRA_1554 SGRA_1554 rpoE-5 rpoE-5 rpoE-6 rpoE-6 rpoS rpoS mfd mfd fnr fnr SGRA_1732 SGRA_1732 rpoE-7 rpoE-7 SGRA_1788 SGRA_1788 SGRA_1866 SGRA_1866 SGRA_1892 SGRA_1892 SGRA_1935 SGRA_1935 SGRA_1937 SGRA_1937 greA greA SGRA_2093 SGRA_2093 SGRA_2114 SGRA_2114 SGRA_2152 SGRA_2152 SGRA_2160 SGRA_2160 SGRA_2161 SGRA_2161 SGRA_2162 SGRA_2162 SGRA_2167 SGRA_2167 SGRA_2168 SGRA_2168 SGRA_2169 SGRA_2169 SGRA_2285 SGRA_2285 nusG nusG pal-3 pal-3 SGRA_2395 SGRA_2395 SGRA_2396 SGRA_2396 rpoE-8 rpoE-8 SGRA_2415 SGRA_2415 SGRA_2416 SGRA_2416 rpoE-9 rpoE-9 SGRA_2500 SGRA_2500 SGRA_2521 SGRA_2521 hupB-2 hupB-2 SGRA_2648 SGRA_2648 oxyR oxyR SGRA_2699 SGRA_2699 troR troR lrp lrp SGRA_2979 SGRA_2979 fur-2 fur-2 SGRA_3138 SGRA_3138 SGRA_3207 SGRA_3207 SGRA_3208 SGRA_3208 SGRA_3209 SGRA_3209 SGRA_3210 SGRA_3210 SGRA_3211 SGRA_3211 SGRA_3212 SGRA_3212 SGRA_3213 SGRA_3213 cheY cheY rpoN rpoN rpoE-10 rpoE-10 SGRA_3372 SGRA_3372 pilH pilH phoB1-2 phoB1-2 SGRA_3560 SGRA_3560 SGRA_3596 SGRA_3596 nusB nusB SGRA_3650 SGRA_3650 SGRA_3651 SGRA_3651 SGRA_3662 SGRA_3662 SGRA_3663 SGRA_3663 SGRA_3683 SGRA_3683 oxyR-2 oxyR-2 SGRA_3852 SGRA_3852 oxyR-3 oxyR-3 SGRA_3882 SGRA_3882 SGRA_4027 SGRA_4027 SGRA_4073 SGRA_4073 SGRA_4095 SGRA_4095 SGRA_4102 SGRA_4102 rpoE-11 rpoE-11 asnC asnC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpoE-4RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
nusATranscription elongation factor NusA; Participates in both transcription termination and antitermination. (438 aa)
SGRA_1132Two component, sigma54 specific, Fis family transcriptional regulator; COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain. (534 aa)
SGRA_1158Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (231 aa)
SGRA_1244Hypothetical protein. (237 aa)
SGRA_1246AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (280 aa)
SGRA_1250Type 4 fimbriae expression regulatory protein PilR; COG3283 Transcriptional regulator of aromatic amino acids metabolism. (300 aa)
SGRA_1255Type 4 fimbriae expression regulatory protein PilR; COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain. (608 aa)
pleC1Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase. (678 aa)
SGRA_0043Type 4 fimbriae expression regulatory protein pilR; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (549 aa)
SGRA_0128COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (291 aa)
SGRA_0144Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (310 aa)
SGRA_0197RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
phoB1COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (237 aa)
SGRA_0310COG1733 Predicted transcriptional regulators. (113 aa)
SGRA_0410Transcriptional regulator, Crp/Fnr family protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. (149 aa)
SGRA_0451Hypothetical protein. (836 aa)
SGRA_0518Hypothetical protein. (105 aa)
SGRA_0546Putative transcriptional regulator, Crp/Fnr family; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. (190 aa)
SGRA_0571Anti-anti-sigma regulatory factor; COG0840 Methyl-accepting chemotaxis protein. (287 aa)
SGRA_0576COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (132 aa)
degSMulti-sensor signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain. (1047 aa)
narLTwo component transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (219 aa)
rpoERNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (172 aa)
SGRA_0626COG5343 Uncharacterized protein conserved in bacteria. (281 aa)
furFerric-uptake regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. (154 aa)
SGRA_0696COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family. (116 aa)
SGRA_0705Organic hydroperoxide resistance transcriptionalregulator; COG1846 Transcriptional regulators. (146 aa)
rpoE-2RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
SGRA_0735Penicillinase repressor; COG3682 Predicted transcriptional regulator. (108 aa)
SGRA_0764Putative two component, sigma54 specific, transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (421 aa)
rpoDRNA polymerase, sigma 70 subunit, RpoD subfamily protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)
SGRA_0789Hypothetical protein. (124 aa)
mraZMraZ protein; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family. (153 aa)
SGRA_1024Zinc finger SWIM domain protein. (534 aa)
rpoE-3RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (152 aa)
hupBDNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (108 aa)
SGRA_1293COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (290 aa)
birACOG0340 Biotin-(acetyl-CoA carboxylase) ligase. (272 aa)
SGRA_1375RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
SGRA_1410Transcriptional regulator, ArsR family protein; COG0640 Predicted transcriptional regulators. (111 aa)
SGRA_1412Transcriptional regulator, ArsR family protein; COG0640 Predicted transcriptional regulators. (78 aa)
SGRA_1467Regulatory protein ArsR; COG0640 Predicted transcriptional regulators. (112 aa)
SGRA_1541COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (241 aa)
SGRA_1554Transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (281 aa)
rpoE-5COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (213 aa)
rpoE-6RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa)
rpoSPutative RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1122 aa)
fnrCRP family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. (223 aa)
SGRA_1732RNA polymerase, sigma-E factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
rpoE-7RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
SGRA_1788Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. (294 aa)
SGRA_1866Hypothetical protein. (189 aa)
SGRA_1892COG2207 AraC-type DNA-binding domain-containing proteins. (296 aa)
SGRA_1935LexA DNA-binding protein; COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen. (446 aa)
SGRA_1937COG0506 Proline dehydrogenase. (362 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (160 aa)
SGRA_2093Two component transcriptional regulator, LuxR family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (289 aa)
SGRA_2114Transcriptional regulator, BadM/Rrf2 family protein; COG1959 Predicted transcriptional regulator. (145 aa)
SGRA_2152COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (135 aa)
SGRA_2160COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (289 aa)
SGRA_2161COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (284 aa)
SGRA_2162COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (296 aa)
SGRA_2167COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (286 aa)
SGRA_2168COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (290 aa)
SGRA_2169COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (283 aa)
SGRA_2285RNA polymerase sigma factor, sigma-70 family protein; COG1191 DNA-directed RNA polymerase specialized sigma subunit. (199 aa)
nusGNusG antitermination factor; Participates in transcription elongation, termination and antitermination. (180 aa)
pal-3OmpA/MotB domain-containing protein; COG0457 FOG: TPR repeat. (675 aa)
SGRA_2395ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa)
SGRA_2396anti-FecI sigma factor, FecR; COG3712 Fe2+-dicitrate sensor, membrane component. (339 aa)
rpoE-8RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
SGRA_2415Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. (151 aa)
SGRA_2416Transcriptional regulator, XRE family; COG1813 Predicted transcription factor, homolog of eukaryotic MBF1. (105 aa)
rpoE-9COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
SGRA_2500Sigma54 specific transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (433 aa)
SGRA_2521Hypothetical protein; COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit. (105 aa)
hupB-2COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. (106 aa)
SGRA_2648COG0640 Predicted transcriptional regulators. (99 aa)
oxyRRedox-sensitive transcriptional activator OxyR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (308 aa)
SGRA_2699COG1846 Transcriptional regulators. (216 aa)
troRIron dependent repressor; COG1321 Mn-dependent transcriptional regulator. (223 aa)
lrpTranscriptional regulator, AsnC family protein; COG1522 Transcriptional regulators. (165 aa)
SGRA_2979Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins. (288 aa)
fur-2Fur family transcriptional regulator protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. (139 aa)
SGRA_3138Hypothetical protein. (509 aa)
SGRA_3207Transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (239 aa)
SGRA_3208Two component transcriptional regulator, LuxR family; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (175 aa)
SGRA_3209COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family. (99 aa)
SGRA_3210Anti-anti-sigma regulatory factor; COG0840 Methyl-accepting chemotaxis protein. (291 aa)
SGRA_3211COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (119 aa)
SGRA_3212Switch protein/serine-threonine kinase; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (132 aa)
SGRA_3213Putative anti-sigma regulatory factor, serine/threonine protein kinase; COG0656 Aldo/keto reductases, related to diketogulonate reductase. (200 aa)
cheYChemotaxis response regulator (CheY); COG0784 FOG: CheY-like receiver. (127 aa)
rpoNCOG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog. (539 aa)
rpoE-10RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
SGRA_3372Transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (303 aa)
pilHTwo-component system response regulator; COG0784 FOG: CheY-like receiver. (122 aa)
phoB1-2Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (235 aa)
SGRA_3560COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (291 aa)
SGRA_3596COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (211 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (311 aa)
SGRA_3650rsbR, positive regulator of sigma-B; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (286 aa)
SGRA_3651COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (289 aa)
SGRA_3662Hypothetical protein. (278 aa)
SGRA_3663Hypothetical protein. (270 aa)
SGRA_3683Hypothetical protein; COG0457 FOG: TPR repeat. (317 aa)
oxyR-2Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (314 aa)
SGRA_3852Anti-anti-sigma regulatory factor; COG0840 Methyl-accepting chemotaxis protein. (288 aa)
oxyR-3Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (315 aa)
SGRA_3882COG1510 Predicted transcriptional regulators; Belongs to the GbsR family. (218 aa)
SGRA_4027Putative transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (292 aa)
SGRA_4073Hypothetical protein; COG2378 Predicted transcriptional regulator. (338 aa)
SGRA_4095Hypothetical protein. (358 aa)
SGRA_4102rsbR, positive regulator of sigma-B; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (333 aa)
rpoE-11COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa)
asnCTranscriptional regulator, AsnC family protein; COG1522 Transcriptional regulators. (160 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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