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| | SGRA_2981 | Hypothetical protein. (286 aa) |
| | ychF | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (367 aa) |
| | trxB-2 | COG0492 Thioredoxin reductase. (313 aa) |
| | mutL | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (622 aa) |
| | SGRA_2901 | Hypothetical protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA. (678 aa) |
| | ahpC | COG0450 Peroxiredoxin. (183 aa) |
| | sprA | Gliding motility protein SprA. (2512 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa) |
| | SGRA_2609 | COG1988 Predicted membrane-bound metal-dependent hydrolases. (398 aa) |
| | mutS2 | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (800 aa) |
| | xthA | Exodeoxyribonuclease III Xth; COG0708 Exonuclease III. (257 aa) |
| | SGRA_2572 | SMC domain protein; COG4637 Predicted ATPase. (454 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa) |
| | dcm | DNA-cytosine methyltransferase; COG0270 Site-specific DNA methylase. (418 aa) |
| | uvrA-2 | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (930 aa) |
| | flgJ-2 | Mannosyl-glycoprotein endo-beta-n-acetylglucosamidase; COG1705 Muramidase (flagellum-specific). (477 aa) |
| | SGRA_2251 | DNA mismatch repair protein MutS domain-containing protein; COG0249 Mismatch repair ATPase (MutS family). (589 aa) |
| | SGRA_2219 | Hypothetical protein. (358 aa) |
| | mutY | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (402 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (943 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (884 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (702 aa) |
| | SGRA_2082 | Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; COG1705 Muramidase (flagellum-specific). (346 aa) |
| | SGRA_2047 | Hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (365 aa) |
| | SGRA_2039 | Hypothetical protein; Belongs to the SOS response-associated peptidase family. (216 aa) |
| | recA | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (372 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (177 aa) |
| | SGRA_1950 | Lipoprotein; COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance. (249 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (680 aa) |
| | SGRA_1751 | Hypothetical protein. (256 aa) |
| | SGRA_1715 | ATP-binding protein; COG1106 Predicted ATPases. (434 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1122 aa) |
| | recN | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (552 aa) |
| | recQ-2 | COG0514 Superfamily II DNA helicase. (737 aa) |
| | trxB | COG0492 Thioredoxin reductase. (339 aa) |
| | recJ | COG0608 Single-stranded DNA-specific exonuclease. (564 aa) |
| | SGRA_1355 | Smr protein/MutS2; COG1193 Mismatch repair ATPase (MutS family). (365 aa) |
| | uvrC | Uvrabc system protein c; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (603 aa) |
| | phrB | COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (466 aa) |
| | flgJ | COG1705 Muramidase (flagellum-specific). (202 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (392 aa) |
| | msrB-2 | Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family. (131 aa) |
| | recO | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (238 aa) |
| | msrB | methionine-R-sulfoxide reductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase. (175 aa) |
| | SGRA_1025 | ATP-dependent DNA ligase. (1056 aa) |
| | SGRA_1023 | RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (554 aa) |
| | SGRA_0994 | 2OG-Fe(II) oxygenase; COG3145 Alkylated DNA repair protein. (212 aa) |
| | recQ | ATP-dependent DNA helicase, RecQ family protein; COG0514 Superfamily II DNA helicase. (2930 aa) |
| | katE | COG0753 Catalase; Belongs to the catalase family. (504 aa) |
| | SGRA_0932 | CRISPR-associated protein, putative. (120 aa) |
| | SGRA_0931 | Hypothetical protein. (350 aa) |
| | SGRA_0814 | ATPase-like protein; COG1106 Predicted ATPases. (1555 aa) |
| | SGRA_0809 | Alkyl hydroperoxide reductase, F52a subunit; COG0492 Thioredoxin reductase. (301 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (227 aa) |
| | SGRA_0786 | Hypothetical protein; COG4570 Holliday junction resolvase. (186 aa) |
| | ung | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (226 aa) |
| | SGRA_0737 | Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; COG1705 Muramidase (flagellum-specific). (183 aa) |
| | nfi | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (229 aa) |
| | SGRA_0329 | 2OG-Fe(II) oxygenase; COG3751 Predicted proline hydroxylase. (195 aa) |
| | sodA-2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (203 aa) |
| | SGRA_0400 | AAA ATPase. (287 aa) |
| | SGRA_0401 | SMC domain protein; COG3950 Predicted ATP-binding protein involved in virulence. (532 aa) |
| | SGRA_0403 | AAA ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (440 aa) |
| | recF | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (372 aa) |
| | SGRA_0448 | CRISPR-associated protein, TM1812 family. (441 aa) |
| | SGRA_0450 | CRISPR-associated protein, TM1812 family. (407 aa) |
| | SGRA_0453 | CRISPR-associated RAMP protein; COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily). (558 aa) |
| | SGRA_0454 | Hypothetical protein. (498 aa) |
| | SGRA_0455 | COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily). (194 aa) |
| | SGRA_0456 | Hypothetical protein. (591 aa) |
| | SGRA_0706 | Organic hydroperoxide resistance protein; COG1764 Predicted redox protein, regulator of disulfide bond formation. (137 aa) |
| | dpx | PHP domain protein; COG1796 DNA polymerase IV (family X). (556 aa) |
| | SGRA_0023 | Hypothetical protein. (348 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (804 aa) |
| | SGRA_0100 | COG4268 McrBC 5-methylcytosine restriction system component. (398 aa) |
| | SGRA_0181 | AAA ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (427 aa) |
| | SGRA_0213 | CRISPR-associated RAMP protein, Csm5 family; COG1332 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily). (404 aa) |
| | SGRA_0214 | CRISPR-associated RAMP protein, Csm4 family; COG1567 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily). (366 aa) |
| | SGRA_0215 | CRISPR-associated RAMP Csm3 family protein; COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily). (248 aa) |
| | SGRA_0216 | Csm2 family CRISPR-associated protein; COG1421 Uncharacterized protein predicted to be involved in DNA repair. (156 aa) |
| | SGRA_0217 | CRISPR-associated protein, Csm1 family; COG1353 Predicted hydrolase of the HD superfamily (permuted catalytic motifs). (903 aa) |
| | SGRA_0244 | Hypothetical protein; COG1106 Predicted ATPases. (399 aa) |
| | sodA | Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (256 aa) |
| | ycaJ | Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. (424 aa) |
| | hsdS-3 | Type I restriction-modification system; COG0732 Restriction endonuclease S subunits. (430 aa) |
| | SGRA_4131 | ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (751 aa) |
| | SGRA_4128 | COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases. (1036 aa) |
| | SGRA_3935 | Peroxiredoxin; COG0386 Glutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa) |
| | hsdR-3 | Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1070 aa) |
| | SGRA_3894 | SMC domain-containing protein; COG3950 Predicted ATP-binding protein involved in virulence. (441 aa) |
| | hsdS-2 | COG0732 Restriction endonuclease S subunits. (385 aa) |
| | apaG | Co2+/Mg2+ efflux protein ApaG; COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. (129 aa) |
| | katE-2 | COG0753 Catalase. (576 aa) |
| | SGRA_3869 | SMC domain-containing protein; COG3950 Predicted ATP-binding protein involved in virulence. (433 aa) |
| | SGRA_3697 | CRISPR-associated protein Cas6; COG1583 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily). (273 aa) |
| | SGRA_3658 | COG3022 Uncharacterized protein conserved in bacteria; Belongs to the UPF0246 family. (250 aa) |
| | hsdS | Restriction modification system DNA specificity domain protein; COG0732 Restriction endonuclease S subunits. (383 aa) |
| | SGRA_3606 | Hypothetical protein. (429 aa) |
| | sms | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (464 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (927 aa) |
| | phrB-2 | COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (445 aa) |
| | SGRA_3417 | Type I restriction modification enzyme protein S; COG0732 Restriction endonuclease S subunits. (364 aa) |
| | SGRA_3410 | COG1555 DNA uptake protein and related DNA-binding proteins. (283 aa) |
| | SGRA_3404 | ATPase-like protein; COG4637 Predicted ATPase. (354 aa) |
| | hslR | COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog). (139 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (710 aa) |
| | msrA | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (182 aa) |
| | SGRA_3264 | Hypothetical protein. (205 aa) |
| | SGRA_3257 | Hypothetical protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. (371 aa) |
| | SGRA_0275 | COG1343 Uncharacterized protein predicted to be involved in DNA repair. (98 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (321 aa) |
| | hsdR | Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. (936 aa) |
| | SGRA_0305 | COG4268 McrBC 5-methylcytosine restriction system component. (408 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (202 aa) |
| | SGRA_3072 | COG2149 Predicted membrane protein. (106 aa) |
| | ybaZ | methylated-DNA-[protein]-cysteine S-methyltransferase; COG0350 Methylated DNA-protein cysteine methyltransferase. (104 aa) |
| | SGRA_3038 | Hypothetical protein; COG1403 Restriction endonuclease. (319 aa) |
| | SGRA_3037 | SMC domain protein; COG1122 ABC-type cobalt transport system, ATPase component. (620 aa) |
| | SGRA_2984 | AAA ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (399 aa) |
| | SGRA_2982 | COG1555 DNA uptake protein and related DNA-binding proteins. (689 aa) |
