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| | moxR | COG0714 MoxR-like ATPases. (331 aa) |
| | ftsH | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (675 aa) |
| | SGRA_1355 | Smr protein/MutS2; COG1193 Mismatch repair ATPase (MutS family). (365 aa) |
| | SGRA_1366 | Chromosome segregation ATPase-like protein; COG3210 Large exoproteins involved in heme utilization or adhesion. (109 aa) |
| | SGRA_1510 | Hypothetical protein. (497 aa) |
| | SGRA_1545 | Metallophosphoesterase; COG2908 Uncharacterized protein conserved in bacteria. (281 aa) |
| | moxR-2 | ATPase associated with various cellular activities AAA_3; COG0714 MoxR-like ATPases. (320 aa) |
| | SGRA_1715 | ATP-binding protein; COG1106 Predicted ATPases. (434 aa) |
| | spoVK | Stage V sporulation protein K; COG0464 ATPases of the AAA+ class. (875 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (680 aa) |
| | SGRA_1813 | AAA ATPase central domain protein; COG0464 ATPases of the AAA+ class. (462 aa) |
| | fusA | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (710 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (526 aa) |
| | SGRA_1902 | Hypothetical protein. (421 aa) |
| | trmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (455 aa) |
| | SGRA_1972 | Chromosome segregation ATPase-like protein. (1125 aa) |
| | arsA | Arsenite-activated ATPase (arsA) subfamily protein; COG0003 Oxyanion-translocating ATPase. (384 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (702 aa) |
| | typA | GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response. (607 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (943 aa) |
| | SGRA_2172 | Hypothetical protein. (1718 aa) |
| | SGRA_2267 | COG2035 Predicted membrane protein. (302 aa) |
| | SGRA_3404 | ATPase-like protein; COG4637 Predicted ATPase. (354 aa) |
| | SGRA_3606 | Hypothetical protein. (429 aa) |
| | SGRA_3694 | Putative lipoprotein. (291 aa) |
| | mazG | Nucleoside triphosphate pyrophosphohydrolase; COG1694 Predicted pyrophosphatase. (254 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa) |
| | SGRA_3869 | SMC domain-containing protein; COG3950 Predicted ATP-binding protein involved in virulence. (433 aa) |
| | SGRA_3894 | SMC domain-containing protein; COG3950 Predicted ATP-binding protein involved in virulence. (441 aa) |
| | SGRA_3908 | COG0542 ATPases with chaperone activity, ATP-binding subunit. (1098 aa) |
| | SGRA_3937 | COG0542 ATPases with chaperone activity, ATP-binding subunit. (1098 aa) |
| | SGRA_3961 | Nudix hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (184 aa) |
| | smc | Chromosome segregation protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1173 aa) |
| | SGRA_4085 | Hypothetical protein. (181 aa) |
| | SGRA_4129 | Hypothetical protein. (137 aa) |
| | SGRA_4131 | ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (751 aa) |
| | uvrD-2 | COG0210 Superfamily I DNA and RNA helicases. (759 aa) |
| | recQ | ATP-dependent DNA helicase, RecQ family protein; COG0514 Superfamily II DNA helicase. (2930 aa) |
| | mcrB | ATPase associated with various cellular activities AAA_5; COG1401 GTPase subunit of restriction endonuclease. (549 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (1002 aa) |
| | ppa | COG0221 Inorganic pyrophosphatase. (209 aa) |
| | tufA | Translation elongation factor 1a (ef-1a/ef-tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (395 aa) |
| | SGRA_2329 | Putative deoxyribonucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (195 aa) |
| | ftsY | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (322 aa) |
| | maf | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (205 aa) |
| | uvrA-2 | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (930 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (596 aa) |
| | hflX | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (403 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa) |
| | SGRA_2572 | SMC domain protein; COG4637 Predicted ATPase. (454 aa) |
| | mutS2 | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (800 aa) |
| | era | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (299 aa) |
| | argK | Arginine/ornithine transport system ATPase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family. (360 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa) |
| | htpG | ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity. (619 aa) |
| | rsgA | GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (312 aa) |
| | dnaB | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (510 aa) |
| | clpB | ATP-dependent chaperone ClpB; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (878 aa) |
| | copA | Heavy metal translocating p-type atpase; COG2217 Cation transport ATPase. (739 aa) |
| | moxR-3 | MoxR-like ATPase, regulator; COG0714 MoxR-like ATPases. (343 aa) |
| | SGRA_2901 | Hypothetical protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA. (678 aa) |
| | mutL | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (622 aa) |
| | ychF | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (367 aa) |
| | SGRA_2984 | AAA ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (399 aa) |
| | SGRA_3037 | SMC domain protein; COG1122 ABC-type cobalt transport system, ATPase component. (620 aa) |
| | SGRA_3038 | Hypothetical protein; COG1403 Restriction endonuclease. (319 aa) |
| | SGRA_3086 | COG0464 ATPases of the AAA+ class. (868 aa) |
| | SGRA_3100 | MoxR-like protein ATPase-like protein; COG0714 MoxR-like ATPases. (372 aa) |
| | SGRA_3127 | Nudix hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (218 aa) |
| | SGRA_3137 | ATPase; COG0714 MoxR-like ATPases. (366 aa) |
| | SGRA_3152 | COG3210 Large exoproteins involved in heme utilization or adhesion. (103 aa) |
| | recB | UvrD/REP helicase; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). (1091 aa) |
| | SGRA_3257 | Hypothetical protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. (371 aa) |
| | SGRA_3293 | ATPase; COG0017 Aspartyl/asparaginyl-tRNA synthetases. (1654 aa) |
| | SGRA_3305 | Hypothetical protein. (499 aa) |
| | ffh | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (447 aa) |
| | clpX | Sigma 54 interacting domain protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (419 aa) |
| | bacA | Putative bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (320 aa) |
| | djlA | COG1076 DnaJ-domain-containing proteins 1. (252 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (804 aa) |
| | SGRA_0244 | Hypothetical protein; COG1106 Predicted ATPases. (399 aa) |
| | SGRA_0306 | TPR repeat-containing protein; COG1401 GTPase subunit of restriction endonuclease. (825 aa) |
| | SGRA_0344 | Signal peptidase I. (114 aa) |
| | mrp | ATP-binding protein, Mrp/Nbp35 family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa) |
| | SGRA_0380 | Pseudouridine synthase, Rsu; COG3210 Large exoproteins involved in heme utilization or adhesion. (110 aa) |
| | SGRA_0400 | AAA ATPase. (287 aa) |
| | SGRA_0401 | SMC domain protein; COG3950 Predicted ATP-binding protein involved in virulence. (532 aa) |
| | SGRA_0403 | AAA ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (440 aa) |
| | SGRA_0414 | COG0542 ATPases with chaperone activity, ATP-binding subunit. (753 aa) |
| | scpB | Condensin subunit scpb; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (189 aa) |
| | clpC | ATPase AAA-2 domain protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (847 aa) |
| | obgE | GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (335 aa) |
| | SGRA_0769 | Hypothetical protein. (356 aa) |
| | lpxH | Metallophosphoesterase; COG2908 Uncharacterized protein conserved in bacteria. (265 aa) |
| | SGRA_0814 | ATPase-like protein; COG1106 Predicted ATPases. (1555 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (463 aa) |
