STRINGSTRING
hmp hmp fabI-2 fabI-2 SGRA_2080 SGRA_2080 SGRA_2071 SGRA_2071 SGRA_2045 SGRA_2045 SGRA_2036 SGRA_2036 cydB cydB cydA cydA SGRA_1964 SGRA_1964 ald ald SGRA_1937 SGRA_1937 SGRA_1936 SGRA_1936 serA-2 serA-2 galE galE SGRA_1893 SGRA_1893 sucA sucA SGRA_1770 SGRA_1770 ugd ugd aroE aroE SGRA_1563 SGRA_1563 yhfA yhfA SGRA_1515 SGRA_1515 SGRA_1513 SGRA_1513 SGRA_1512 SGRA_1512 SGRA_1511 SGRA_1511 coxB coxB coxA coxA coxC-2 coxC-2 coxC coxC metF metF trxB trxB SGRA_1446 SGRA_1446 SGRA_1437 SGRA_1437 SGRA_1428 SGRA_1428 fabI fabI SGRA_1373 SGRA_1373 pdhA pdhA SGRA_1245 SGRA_1245 msrB-2 msrB-2 SGRA_1144 SGRA_1144 gapA gapA SGRA_1131 SGRA_1131 SGRA_1096 SGRA_1096 phhA phhA SGRA_1090 SGRA_1090 SGRA_1077 SGRA_1077 SGRA_1067 SGRA_1067 crtR crtR msrB msrB SGRA_1051 SGRA_1051 hemN hemN SGRA_0994 SGRA_0994 SGRA_0982 SGRA_0982 mdh mdh katE katE SGRA_0953 SGRA_0953 SGRA_0951 SGRA_0951 nrdB nrdB nrdA nrdA SGRA_0936 SGRA_0936 rfbD rfbD gabD gabD SGRA_0828 SGRA_0828 SGRA_0809 SGRA_0809 SGRA_0746 SGRA_0746 lpd lpd SGRA_0716 SGRA_0716 icd icd SGRA_0706 SGRA_0706 SGRA_0690 SGRA_0690 SGRA_0669 SGRA_0669 SGRA_0607 SGRA_0607 serA serA SGRA_0585 SGRA_0585 SGRA_0559 SGRA_0559 SGRA_0526 SGRA_0526 SGRA_0516 SGRA_0516 SGRA_0515 SGRA_0515 SGRA_0509 SGRA_0509 SGRA_0462 SGRA_0462 SGRA_0379 SGRA_0379 sodA-2 sodA-2 trxA trxA SGRA_0360 SGRA_0360 SGRA_0329 SGRA_0329 SGRA_0311 SGRA_0311 SGRA_0280 SGRA_0280 sodA sodA SGRA_0222 SGRA_0222 SGRA_0204 SGRA_0204 mdaB mdaB SGRA_0133 SGRA_0133 SGRA_0074 SGRA_0074 proC proC SGRA_0017 SGRA_0017 SGRA_0005 SGRA_0005 SGRA_3958 SGRA_3958 SGRA_2764 SGRA_2764 SGRA_2757 SGRA_2757 SGRA_2707 SGRA_2707 SGRA_2706 SGRA_2706 ahpC ahpC ahpD ahpD SGRA_2632 SGRA_2632 SGRA_2612 SGRA_2612 SGRA_2611 SGRA_2611 SGRA_2610 SGRA_2610 folD folD SGRA_2594 SGRA_2594 asd asd pdhB pdhB ahpC-3 ahpC-3 SGRA_4195 SGRA_4195 SGRA_4186 SGRA_4186 SGRA_4154 SGRA_4154 SGRA_4153 SGRA_4153 SGRA_4124 SGRA_4124 glpA glpA lpd-2 lpd-2 hemF hemF SGRA_4028 SGRA_4028 SGRA_4013 SGRA_4013 SGRA_4009 SGRA_4009 wbpO wbpO SGRA_3989 SGRA_3989 gapA-2 gapA-2 SGRA_3965 SGRA_3965 SGRA_2537 SGRA_2537 SGRA_2522 SGRA_2522 fadJ fadJ SGRA_2515 SGRA_2515 SGRA_2469 SGRA_2469 SGRA_2394 SGRA_2394 SGRA_2392 SGRA_2392 SGRA_2387 SGRA_2387 hemA hemA SGRA_2328 SGRA_2328 SGRA_2281 SGRA_2281 pdxA pdxA pdxH pdxH SGRA_2262 SGRA_2262 SGRA_2261 SGRA_2261 SGRA_2259 SGRA_2259 sdhB sdhB sdhA sdhA sdhC sdhC SGRA_2249 SGRA_2249 SGRA_2223 SGRA_2223 SGRA_2187 SGRA_2187 SGRA_2186 SGRA_2186 SGRA_3935 SGRA_3935 dps-2 dps-2 dapB dapB katE-2 katE-2 SGRA_3861 SGRA_3861 SGRA_3856 SGRA_3856 SGRA_3845 SGRA_3845 ahpC-2 ahpC-2 guaC guaC sfcA sfcA SGRA_3761 SGRA_3761 hmgA hmgA SGRA_3738 SGRA_3738 SGRA_3716 SGRA_3716 SGRA_3625 SGRA_3625 fcl fcl gpsA gpsA SGRA_3587 SGRA_3587 fabG-2 fabG-2 SGRA_3561 SGRA_3561 SGRA_3529 SGRA_3529 SGRA_3526 SGRA_3526 SGRA_3525 SGRA_3525 SGRA_3483 SGRA_3483 SGRA_3479 SGRA_3479 SGRA_3478 SGRA_3478 SGRA_3458 SGRA_3458 SGRA_3457 SGRA_3457 idi idi SGRA_3436 SGRA_3436 SGRA_3391 SGRA_3391 SGRA_3373 SGRA_3373 nadB nadB SGRA_3354 SGRA_3354 SGRA_3352 SGRA_3352 SGRA_3350 SGRA_3350 msrA msrA glcD glcD paaE paaE SGRA_3188 SGRA_3188 gcvP gcvP SGRA_3154 SGRA_3154 SGRA_3129 SGRA_3129 folA folA fixA fixA fixB fixB trxA-2 trxA-2 SGRA_3095 SGRA_3095 dps dps rfbD-2 rfbD-2 nqrF nqrF nqrE nqrE nqrD nqrD nqrC nqrC nqrB nqrB nqrA nqrA mtnD mtnD SGRA_3003 SGRA_3003 SGRA_2998 SGRA_2998 gcdH gcdH miaE miaE trxB-2 trxB-2 SGRA_2923 SGRA_2923 SGRA_2915 SGRA_2915 SGRA_2908 SGRA_2908 fabG fabG paaH paaH SGRA_2841 SGRA_2841 SGRA_2810 SGRA_2810 icd-2 icd-2 murB murB SGRA_2150 SGRA_2150 queG queG
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hmpGlobin; COG1017 Hemoglobin-like flavoprotein; Belongs to the globin family. (389 aa)
fabI-2COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH). (294 aa)
SGRA_2080Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (233 aa)
SGRA_2071COG0778 Nitroreductase. (196 aa)
SGRA_2045Glu/Leu/Phe/Val dehydrogenase family protein; COG0334 Glutamate dehydrogenase/leucine dehydrogenase. (409 aa)
SGRA_2036Cytochrome oxidase assembly; COG1612 Uncharacterized protein required for cytochrome oxidase assembly. (383 aa)
cydBCOG1294 Cytochrome bd-type quinol oxidase, subunit 2. (338 aa)
cydACOG1271 Cytochrome bd-type quinol oxidase, subunit 1. (459 aa)
SGRA_1964NADPH-dependent FMN reductase; COG0431 Predicted flavoprotein. (180 aa)
aldCOG0686 Alanine dehydrogenase. (407 aa)
SGRA_1937COG0506 Proline dehydrogenase. (362 aa)
SGRA_19363-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (665 aa)
serA-2D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (340 aa)
galENAD dependent epimerase; COG0451 Nucleoside-diphosphate-sugar epimerases. (330 aa)
SGRA_1893COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (506 aa)
sucACOG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (922 aa)
SGRA_1770General stress protein; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). (130 aa)
ugdNucleotide sugar dehydrogenase; COG1004 Predicted UDP-glucose 6-dehydrogenase. (440 aa)
aroECOG0169 Shikimate 5-dehydrogenase. (273 aa)
SGRA_1563Short-chain dehydrogenase/reductase sdr; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (232 aa)
yhfACOG1765 Predicted redox protein, regulator of disulfide bond formation. (139 aa)
SGRA_1515COG2857 Cytochrome c1. (486 aa)
SGRA_1513Polysulfide reductase NrfD; COG5557 Polysulphide reductase. (471 aa)
SGRA_1512Hypothetical protein. (177 aa)
SGRA_1511COG2010 Cytochrome c, mono- and diheme variants. (252 aa)
coxBCytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (462 aa)
coxACytochrome-c oxidase; COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family. (619 aa)
coxC-2COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3. (171 aa)
coxCCOG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3. (330 aa)
metFCOG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (318 aa)
trxBCOG0492 Thioredoxin reductase. (339 aa)
SGRA_1446Beta-lactamase domain protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (468 aa)
SGRA_1437Alkyl hydroperoxide reductase/ thiol specific antioxidant/ mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins. (415 aa)
SGRA_1428Hypothetical protein. (422 aa)
fabIShort-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (261 aa)
SGRA_1373COG1981 Predicted membrane protein. (188 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (335 aa)
SGRA_1245Alcohol dehydrogenase zinc-binding domain protein; COG1064 Zn-dependent alcohol dehydrogenases. (350 aa)
msrB-2Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family. (131 aa)
SGRA_1144faD-dependent pyridine nucleotide-disulfide oxidoreductase; COG2072 Predicted flavoprotein involved in K+ transport. (472 aa)
gapACOG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (495 aa)
SGRA_1131Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (273 aa)
SGRA_1096Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins. (185 aa)
phhACOG3186 Phenylalanine-4-hydroxylase. (245 aa)
SGRA_1090Radical SAM domain-containing protein; COG0641 Arylsulfatase regulator (Fe-S oxidoreductase). (404 aa)
SGRA_1077Hypothetical protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase. (307 aa)
SGRA_1067COG1233 Phytoene dehydrogenase and related proteins. (494 aa)
crtRBeta-carotene hydroxylase. (154 aa)
msrBmethionine-R-sulfoxide reductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase. (175 aa)
SGRA_10514Fe-4S ferredoxin, iron-sulfur binding protein; COG1145 Ferredoxin. (118 aa)
hemNOxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (349 aa)
SGRA_09942OG-Fe(II) oxygenase; COG3145 Alkylated DNA repair protein. (212 aa)
SGRA_0982COG0686 Alanine dehydrogenase. (403 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (374 aa)
katECOG0753 Catalase; Belongs to the catalase family. (504 aa)
SGRA_0953COG3239 Fatty acid desaturase. (377 aa)
SGRA_0951Doxx family protein. (564 aa)
nrdBRibonucleoside-diphosphate reductase small chain; COG0208 Ribonucleotide reductase, beta subunit. (323 aa)
nrdARibonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (803 aa)
SGRA_0936COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. (209 aa)
rfbDPutative dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (292 aa)
gabDCOG1012 NAD-dependent aldehyde dehydrogenases. (453 aa)
SGRA_0828Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins. (389 aa)
SGRA_0809Alkyl hydroperoxide reductase, F52a subunit; COG0492 Thioredoxin reductase. (301 aa)
SGRA_0746Putative zinc-type alcohol dehydrogenase-like protein; COG1064 Zn-dependent alcohol dehydrogenases. (335 aa)
lpdCOG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (472 aa)
SGRA_0716COG1858 Cytochrome c peroxidase. (327 aa)
icdCOG0473 Isocitrate/isopropylmalate dehydrogenase. (481 aa)
SGRA_0706Organic hydroperoxide resistance protein; COG1764 Predicted redox protein, regulator of disulfide bond formation. (137 aa)
SGRA_0690Alcohol dehydrogenase zinc-binding domain protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (336 aa)
SGRA_0669YD repeat protein; COG3209 Rhs family protein. (1437 aa)
SGRA_0607Alkyl hydroperoxide reductase; COG0526 Thiol-disulfide isomerase and thioredoxins. (186 aa)
serACOG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
SGRA_0585YozB protein; COG2322 Predicted membrane protein. (185 aa)
SGRA_0559COG0526 Thiol-disulfide isomerase and thioredoxins. (495 aa)
SGRA_0526FAD dependent oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). (378 aa)
SGRA_0516Alkyl hydroperoxide reductase/ thiol specific antioxidant/ mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins. (235 aa)
SGRA_0515Thioredoxin family protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (203 aa)
SGRA_05092OG-Fe(II) oxygenase; COG3491 Isopenicillin N synthase and related dioxygenases; Belongs to the iron/ascorbate-dependent oxidoreductase family. (318 aa)
SGRA_0462COG3488 Predicted thiol oxidoreductase. (463 aa)
SGRA_0379Hypothetical protein. (150 aa)
sodA-2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (203 aa)
trxAThioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins. (98 aa)
SGRA_0360FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. (414 aa)
SGRA_03292OG-Fe(II) oxygenase; COG3751 Predicted proline hydroxylase. (195 aa)
SGRA_0311COG0778 Nitroreductase. (217 aa)
SGRA_0280COG2010 Cytochrome c, mono- and diheme variants. (121 aa)
sodAManganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (256 aa)
SGRA_0222Thioredoxin family protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (457 aa)
SGRA_0204Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins. (201 aa)
mdaBNAD(P)H dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B). (197 aa)
SGRA_0133Cytochrome c family protein. (203 aa)
SGRA_0074tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (330 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (262 aa)
SGRA_0017COG1960 Acyl-CoA dehydrogenases. (383 aa)
SGRA_0005COG1748 Saccharopine dehydrogenase and related proteins. (452 aa)
SGRA_3958Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG1225 Peroxiredoxin. (152 aa)
SGRA_2764Hypothetical protein. (373 aa)
SGRA_2757Thioredoxin domain-containing protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (93 aa)
SGRA_2707Hypothetical protein. (259 aa)
SGRA_2706COG1858 Cytochrome c peroxidase. (400 aa)
ahpCCOG0450 Peroxiredoxin. (183 aa)
ahpDAlkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (192 aa)
SGRA_2632COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (471 aa)
SGRA_2612Redoxin domain protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (174 aa)
SGRA_2611COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. (538 aa)
SGRA_2610Flavoprotein NADH-dependent oxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (352 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (298 aa)
SGRA_2594COG1956 GAF domain-containing protein. (163 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa)
pdhBTransketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
ahpC-3Antioxidant, AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (221 aa)
SGRA_4195COG1858 Cytochrome c peroxidase. (330 aa)
SGRA_4186Hypothetical protein; Belongs to the UPF0403 family. (139 aa)
SGRA_4154COG1978 Uncharacterized protein conserved in bacteria. (156 aa)
SGRA_4153Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins. (180 aa)
SGRA_4124acyl-CoA reductase. (340 aa)
glpACOG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (554 aa)
lpd-2COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (470 aa)
hemFCOG0408 Coproporphyrinogen III oxidase. (308 aa)
SGRA_4028COG1960 Acyl-CoA dehydrogenases. (613 aa)
SGRA_4013Short-chain dehydrogenase/reductase sdr; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (284 aa)
SGRA_4009SNARE associated Golgi protein-related protein. (202 aa)
wbpONucleotide sugar dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (430 aa)
SGRA_3989phytanoyl-CoA dioxygenase. (315 aa)
gapA-2Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
SGRA_3965COG4539 Predicted membrane protein. (160 aa)
SGRA_2537Glycosyl hydrolase; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor. (1201 aa)
SGRA_2522Putative rhodanese-related sulfurtransferase; COG1054 Predicted sulfurtransferase; Belongs to the UPF0176 family. (408 aa)
fadJ3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (704 aa)
SGRA_2515Thioredoxin family protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (180 aa)
SGRA_2469COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (517 aa)
SGRA_2394Bacterioferritin comigratory protein; COG1225 Peroxiredoxin. (157 aa)
SGRA_2392COG3000 Sterol desaturase. (401 aa)
SGRA_2387Thioredoxin domain protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (295 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (466 aa)
SGRA_2328Putative disulfide-isomerase; COG0526 Thiol-disulfide isomerase and thioredoxins. (802 aa)
SGRA_2281Putative thiol-disulfide oxidoreductase DCC; COG3011 Uncharacterized protein conserved in bacteria. (135 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; COG1995 Pyridoxal phosphate biosynthesis protein; Belongs to the PdxA family. (517 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (223 aa)
SGRA_2262Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG1225 Peroxiredoxin. (203 aa)
SGRA_2261COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. (300 aa)
SGRA_2259MHC_I C-terminus family protein; COG0666 FOG: Ankyrin repeat. (455 aa)
sdhBCOG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (257 aa)
sdhACOG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (667 aa)
sdhCCOG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (207 aa)
SGRA_2249COG1257 Hydroxymethylglutaryl-CoA reductase. (515 aa)
SGRA_2223COG1960 Acyl-CoA dehydrogenases. (598 aa)
SGRA_2187COG0723 Rieske Fe-S protein. (137 aa)
SGRA_2186Hypothetical protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (141 aa)
SGRA_3935Peroxiredoxin; COG0386 Glutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa)
dps-2COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family. (158 aa)
dapBCOG0289 Dihydrodipicolinate reductase; Belongs to the DapB family. (242 aa)
katE-2COG0753 Catalase. (576 aa)
SGRA_3861NADP-dependent L-serine/L-allo-threonine dehydrogenase; COG4221 Short-chain alcohol dehydrogenase of unknown specificity. (737 aa)
SGRA_3856Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG1225 Peroxiredoxin. (205 aa)
SGRA_3845Beta-lactamase domain protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (461 aa)
ahpC-2Antioxidant, AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (219 aa)
guaCGuanosine 5'-monophosphate oxidoreductase; COG0516 IMP dehydrogenase/GMP reductase. (340 aa)
sfcAMalate dehydrogenase; COG0281 Malic enzyme. (403 aa)
SGRA_3761Putative short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (288 aa)
hmgACOG3508 Homogentisate 1,2-dioxygenase. (386 aa)
SGRA_3738COG3239 Fatty acid desaturase. (359 aa)
SGRA_3716Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (181 aa)
SGRA_3625FAD dependent oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). (355 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (301 aa)
gpsACOG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (348 aa)
SGRA_3587Nad(p)h dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B). (193 aa)
fabG-23-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
SGRA_3561Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG1225 Peroxiredoxin. (217 aa)
SGRA_3529COG1960 Acyl-CoA dehydrogenases. (388 aa)
SGRA_3526COG0262 Dihydrofolate reductase. (176 aa)
SGRA_3525COG1012 NAD-dependent aldehyde dehydrogenases. (542 aa)
SGRA_3483Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG1225 Peroxiredoxin. (208 aa)
SGRA_3479COG3182 Uncharacterized iron-regulated membrane protein. (395 aa)
SGRA_3478COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). (327 aa)
SGRA_3458COG1741 Pirin-related protein; Belongs to the pirin family. (287 aa)
SGRA_3457COG0778 Nitroreductase. (207 aa)
idiIsopentenyl pyrophosphate isomerase; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. (341 aa)
SGRA_3436hydroxymethylglutaryl-CoA reductase, degradative; COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (460 aa)
SGRA_3391Monooxygenase FAD-binding protein; COG0644 Dehydrogenases (flavoproteins). (388 aa)
SGRA_3373Putative oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (315 aa)
nadBL-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (534 aa)
SGRA_33545-methylaminomethyl-2-thiouridine methyltransferase. (229 aa)
SGRA_3352Amine oxidase; COG1233 Phytoene dehydrogenase and related proteins. (480 aa)
SGRA_3350Oxidoreductase domain protein. (256 aa)
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (182 aa)
glcD(S)-2-hydroxy-acid oxidase; COG0277 FAD/FMN-containing dehydrogenases. (468 aa)
paaEphenylacetate-CoA oxygenase/reductase, PaaK subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. (367 aa)
SGRA_3188COG1858 Cytochrome c peroxidase. (459 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (975 aa)
SGRA_3154COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3. (208 aa)
SGRA_3129COG1231 Monoamine oxidase. (447 aa)
folADihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (175 aa)
fixACOG2086 Electron transfer flavoprotein, beta subunit. (212 aa)
fixBCOG2025 Electron transfer flavoprotein, alpha subunit. (319 aa)
trxA-2Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. (106 aa)
SGRA_3095Riboflavin biosynthesis protein ribd; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (348 aa)
dpsCOG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family. (167 aa)
rfbD-2COG1091 dTDP-4-dehydrorhamnose reductase. (295 aa)
nqrFNa(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (442 aa)
nqrENa(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (201 aa)
nqrDNa(+)-translocating NADH-quinone reductase subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (221 aa)
nqrCNa(+)-translocating NADH-quinone reductase subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (269 aa)
nqrBNa(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (433 aa)
nqrANa(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (547 aa)
mtnDMethionine salvage pathway protein E-2/E-2'; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (175 aa)
SGRA_3003COG1960 Acyl-CoA dehydrogenases. (599 aa)
SGRA_2998COG2010 Cytochrome c, mono- and diheme variants. (131 aa)
gcdHCOG1960 Acyl-CoA dehydrogenases. (405 aa)
miaEtRNA-hydroxylase; COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA. (200 aa)
trxB-2COG0492 Thioredoxin reductase. (313 aa)
SGRA_2923COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (473 aa)
SGRA_2915COG1233 Phytoene dehydrogenase and related proteins. (490 aa)
SGRA_2908BNR repeat-containing glycosyl hydrolase; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor. (315 aa)
fabG3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (233 aa)
paaHCOG1250 3-hydroxyacyl-CoA dehydrogenase. (296 aa)
SGRA_2841COG0778 Nitroreductase. (210 aa)
SGRA_2810Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins. (401 aa)
icd-2COG0538 Isocitrate dehydrogenases. (399 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (332 aa)
SGRA_2150COG0778 Nitroreductase. (222 aa)
queGIron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (309 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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