STRINGSTRING
mdh mdh SGRA_1245 SGRA_1245 aroE aroE ugd ugd galE galE serA-2 serA-2 SGRA_2080 SGRA_2080 murB murB SGRA_2249 SGRA_2249 fadJ fadJ icd-2 icd-2 paaH paaH rfbD-2 rfbD-2 SGRA_3095 SGRA_3095 SGRA_3373 SGRA_3373 SGRA_3436 SGRA_3436 fabG-2 fabG-2 gpsA gpsA fcl fcl SGRA_3761 SGRA_3761 sfcA sfcA wbpO wbpO serA serA icd icd SGRA_0746 SGRA_0746 rfbD rfbD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (374 aa)
SGRA_1245Alcohol dehydrogenase zinc-binding domain protein; COG1064 Zn-dependent alcohol dehydrogenases. (350 aa)
aroECOG0169 Shikimate 5-dehydrogenase. (273 aa)
ugdNucleotide sugar dehydrogenase; COG1004 Predicted UDP-glucose 6-dehydrogenase. (440 aa)
galENAD dependent epimerase; COG0451 Nucleoside-diphosphate-sugar epimerases. (330 aa)
serA-2D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (340 aa)
SGRA_2080Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (233 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (332 aa)
SGRA_2249COG1257 Hydroxymethylglutaryl-CoA reductase. (515 aa)
fadJ3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (704 aa)
icd-2COG0538 Isocitrate dehydrogenases. (399 aa)
paaHCOG1250 3-hydroxyacyl-CoA dehydrogenase. (296 aa)
rfbD-2COG1091 dTDP-4-dehydrorhamnose reductase. (295 aa)
SGRA_3095Riboflavin biosynthesis protein ribd; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (348 aa)
SGRA_3373Putative oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (315 aa)
SGRA_3436hydroxymethylglutaryl-CoA reductase, degradative; COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (460 aa)
fabG-23-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
gpsACOG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (348 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (301 aa)
SGRA_3761Putative short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (288 aa)
sfcAMalate dehydrogenase; COG0281 Malic enzyme. (403 aa)
wbpONucleotide sugar dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (430 aa)
serACOG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
icdCOG0473 Isocitrate/isopropylmalate dehydrogenase. (481 aa)
SGRA_0746Putative zinc-type alcohol dehydrogenase-like protein; COG1064 Zn-dependent alcohol dehydrogenases. (335 aa)
rfbDPutative dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (292 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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