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SGRA_4071 SGRA_4071 lpxD-2 lpxD-2 lpxA lpxA SGRA_1530 SGRA_1530 gcp gcp pcaF pcaF bcsA bcsA fabI fabI fabZ fabZ SGRA_1401 SGRA_1401 SGRA_1353 SGRA_1353 SGRA_1256 SGRA_1256 SGRA_1151 SGRA_1151 SGRA_1130 SGRA_1130 SGRA_1058 SGRA_1058 atoB-2 atoB-2 SGRA_0703 SGRA_0703 SGRA_0491 SGRA_0491 plsB plsB fabD fabD rimJ rimJ cat cat atoB atoB SGRA_0090 SGRA_0090 lpxC lpxC lpxD lpxD elaA elaA fabI-2 fabI-2 SGRA_2126 SGRA_2126 SGRA_2283 SGRA_2283 fadA fadA fabF fabF sucB sucB fabH fabH fabH-2 fabH-2 yhhY yhhY lipB lipB plsC plsC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGRA_4071GNAT family acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (363 aa)
lpxD-2UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (351 aa)
lpxAUDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (261 aa)
SGRA_1530Hypothetical protein. (218 aa)
gcpUGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (396 aa)
pcaFBeta-ketoadipyl CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
bcsAChalcone and stilbene synthase domain protein; COG3424 Predicted naringenin-chalcone synthase. (352 aa)
fabIShort-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (261 aa)
fabZ(3R)-hydroxymyristoyl-[acyl-carrier- protein]dehydratase; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases. (153 aa)
SGRA_1401Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (427 aa)
SGRA_1353Gcn5-related n-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (147 aa)
SGRA_1256GCN5-like N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins. (179 aa)
SGRA_1151Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (399 aa)
SGRA_1130GCN5-related N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins. (189 aa)
SGRA_1058GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (156 aa)
atoB-2COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
SGRA_0703Gcn5-related n-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (176 aa)
SGRA_0491Hypothetical protein. (246 aa)
plsBCOG2937 Glycerol-3-phosphate O-acyltransferase. (579 aa)
fabDCOG0331 (acyl-carrier-protein) S-malonyltransferase. (293 aa)
rimJribosomal-protein-S5-alanine N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins. (190 aa)
catCOG4845 Chloramphenicol O-acetyltransferase. (206 aa)
atoBacetoacetyl-CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
SGRA_0090COG0110 Acetyltransferase (isoleucine patch superfamily). (189 aa)
lpxC3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (461 aa)
lpxDCOG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. (325 aa)
elaAGCN5-like N-acetyltransferase; COG2153 Predicted acyltransferase. (153 aa)
fabI-2COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH). (294 aa)
SGRA_2126GNAT family acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins. (172 aa)
SGRA_2283Transferase hexapeptide repeat protein; COG0110 Acetyltransferase (isoleucine patch superfamily). (214 aa)
fadACOG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
fabF3-oxoacyl-(acyl-carrier-protein) synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (416 aa)
sucB2-oxoglutarate dehydrogenase, e2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (420 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (352 aa)
fabH-2COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III. (358 aa)
yhhYCOG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (167 aa)
lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (242 aa)
plsCCOG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase. (247 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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