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| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (494 aa) |
| | SGRA_0111 | Gaf sensor signal transduction histidine kinase; COG2203 FOG: GAF domain. (412 aa) |
| | SGRA_0117 | Mannose-1-phosphate guanyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (242 aa) |
| | SGRA_0138 | COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains. (850 aa) |
| | SGRA_0178 | Signal transduction histidine kinase, LytS; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain. (352 aa) |
| | phoR | Histidine kinase; COG0642 Signal transduction histidine kinase. (355 aa) |
| | SGRA_0285 | COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains. (811 aa) |
| | SGRA_0300 | COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains. (691 aa) |
| | SGRA_0326 | Histidine kinase; COG0642 Signal transduction histidine kinase. (1237 aa) |
| | dacA | Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (256 aa) |
| | SGRA_0468 | COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains. (888 aa) |
| | SGRA_0494 | Signal transduction histidine kinase, LytS; COG3275 Putative regulator of cell autolysis. (354 aa) |
| | SGRA_0498 | COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains. (733 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (361 aa) |
| | SGRA_0564 | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. (315 aa) |
| | SGRA_0590 | Gaf sensor signal transduction histidine kinase; COG2203 FOG: GAF domain. (400 aa) |
| | degS | Multi-sensor signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain. (1047 aa) |
| | dpx | PHP domain protein; COG1796 DNA polymerase IV (family X). (556 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (192 aa) |
| | SGRA_0662 | COG2849 Uncharacterized protein conserved in bacteria. (176 aa) |
| | SGRA_0688 | COG2849 Uncharacterized protein conserved in bacteria. (218 aa) |
| | SGRA_0742 | Glutamate-rich protein grpB. (177 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (247 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (417 aa) |
| | SGRA_0933 | Phosphopantetheinyl transferase-like protein; COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (210 aa) |
| | ppnK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (295 aa) |
| | SGRA_1023 | RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (554 aa) |
| | SGRA_1082 | Serine/threonine protein kinase; COG2815 Uncharacterized protein conserved in bacteria. (302 aa) |
| | udk | COG0572 Uridine kinase. (209 aa) |
| | SGRA_1151 | Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (399 aa) |
| | mvaD | COG3407 Mevalonate pyrophosphate decarboxylase. (347 aa) |
| | SGRA_1248 | O-methyltransferase family 2. (231 aa) |
| | pleC1 | Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase. (678 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (593 aa) |
| | SGRA_1279 | Hypothetical protein. (104 aa) |
| | SGRA_1298 | COG2849 Uncharacterized protein conserved in bacteria. (237 aa) |
| | SGRA_1340 | PfkB domain protein; COG0524 Sugar kinases, ribokinase family. (304 aa) |
| | SGRA_1358 | Hypothetical protein. (310 aa) |
| | thiD | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (253 aa) |
| | phoR-2 | Histidine kinase; COG0642 Signal transduction histidine kinase. (500 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (320 aa) |
| | SGRA_1592 | COG0515 Serine/threonine protein kinase. (349 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa) |
| | SGRA_1642 | COG2849 Uncharacterized protein conserved in bacteria. (201 aa) |
| | SGRA_1653 | Membrane associated hydrolase. (851 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (683 aa) |
| | SGRA_1804 | COG0818 Diacylglycerol kinase. (125 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa) |
| | SGRA_1856 | Histidine kinase; COG0642 Signal transduction histidine kinase. (771 aa) |
| | SGRA_1857 | Two component transcriptional regulator, LuxR family protein; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. (280 aa) |
| | manC | COG0836 Mannose-1-phosphate guanylyltransferase. (364 aa) |
| | dnaN | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa) |
| | SGRA_1919 | Death-on-curing family protein; COG3654 Prophage maintenance system killer protein. (152 aa) |
| | pfk | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. (286 aa) |
| | thrB | COG0083 Homoserine kinase. (303 aa) |
| | SGRA_2073 | COG2849 Uncharacterized protein conserved in bacteria. (282 aa) |
| | holB | COG2812 DNA polymerase III, gamma/tau subunits. (385 aa) |
| | SGRA_2092 | Histidine kinase; COG0642 Signal transduction histidine kinase. (728 aa) |
| | SGRA_2115 | Two-component system response regulator; COG0784 FOG: CheY-like receiver. (520 aa) |
| | SGRA_2152 | COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (135 aa) |
| | SGRA_2193 | Hypothetical protein; COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins. (594 aa) |
| | SGRA_2267 | COG2035 Predicted membrane protein. (302 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1276 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1420 aa) |
| | pssA | CDP-diacylglycerol-serine O-phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (248 aa) |
| | SGRA_2356 | Two component regulator propeller domain protein; COG3292 Predicted periplasmic ligand-binding sensor domain. (770 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (342 aa) |
| | SGRA_2434 | Glycosyl transferase family 4; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase. (378 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | SGRA_2503 | Hypothetical protein. (326 aa) |
| | pyk | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa) |
| | pnp | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (747 aa) |
| | SGRA_2546 | DNA-directed RNA polymerase, omega subunit. (113 aa) |
| | comL | Outer membrane assembly lipoprotein YfiO; COG4105 DNA uptake lipoprotein. (270 aa) |
| | SGRA_2567 | TPR repeat-containing protein; COG0457 FOG: TPR repeat. (297 aa) |
| | folK | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (162 aa) |
| | SGRA_2628 | COG1428 Deoxynucleoside kinases. (219 aa) |
| | SGRA_2636 | Hypothetical protein. (288 aa) |
| | sprA | Gliding motility protein SprA. (2512 aa) |
| | SGRA_2730 | Lipopolysaccharide biosynthesis protein. (372 aa) |
| | mvaK1 | COG1577 Mevalonate kinase. (296 aa) |
| | SGRA_2864 | Morn variant repeat-containing protein; COG2849 Uncharacterized protein conserved in bacteria. (238 aa) |
| | SGRA_3022 | Morn variant repeat-containing protein; COG2849 Uncharacterized protein conserved in bacteria. (324 aa) |
| | SGRA_3081 | Putative thioredoxin; COG2849 Uncharacterized protein conserved in bacteria. (644 aa) |
| | rfbA-2 | Nucleotidyl transferase; COG1209 dTDP-glucose pyrophosphorylase. (331 aa) |
| | SGRA_3156 | Hypothetical protein. (473 aa) |
| | SGRA_3212 | Switch protein/serine-threonine kinase; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (132 aa) |
| | SGRA_3213 | Putative anti-sigma regulatory factor, serine/threonine protein kinase; COG0656 Aldo/keto reductases, related to diketogulonate reductase. (200 aa) |
| | cheA | COG0643 Chemotaxis protein histidine kinase and related kinases. (551 aa) |
| | SGRA_3231 | COG2849 Uncharacterized protein conserved in bacteria. (484 aa) |
| | kptA | Phosphate acetyltransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (186 aa) |
| | rpoN | COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog. (539 aa) |
| | SGRA_3250 | Histidine kinase; COG0642 Signal transduction histidine kinase. (394 aa) |
| | holA | COG1466 DNA polymerase III, delta subunit. (356 aa) |
| | cca | COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (476 aa) |
| | anmK | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (370 aa) |
| | SGRA_3379 | COG0286 Type I restriction-modification system methyltransferase subunit. (911 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (695 aa) |
| | lysC | COG0527 Aspartokinases; Belongs to the aspartokinase family. (424 aa) |
| | dnaE | COG0587 DNA polymerase III, alpha subunit. (1176 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (174 aa) |
| | SGRA_3446 | Histidine kinase; COG0591 Na+/proline symporter. (895 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (927 aa) |
| | SGRA_3549 | Histidine kinase; COG0642 Signal transduction histidine kinase. (326 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | SGRA_3733 | COG1428 Deoxynucleoside kinases. (210 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (238 aa) |
| | tdk | COG1435 Thymidine kinase. (184 aa) |
| | SGRA_3791 | Hypothetical protein. (493 aa) |
| | cmk | COG0283 Cytidylate kinase. (237 aa) |
| | SGRA_3836 | Serine/threonine protein kinase. (340 aa) |
| | SGRA_3842 | Nucleotidyl transferase; COG1209 dTDP-glucose pyrophosphorylase. (328 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (191 aa) |
| | SGRA_3885 | Hypothetical protein; COG1561 Uncharacterized stress-induced protein. (287 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa) |
| | SGRA_3933 | 4'-phosphopantetheinyl transferase superfamily protein; COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); Belongs to the P-Pant transferase superfamily. (190 aa) |
| | pgk | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa) |
| | SGRA_4004 | Ribonuclease HII. (897 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa) |
| | SGRA_4184 | Two component regulator propeller domain protein; COG3292 Predicted periplasmic ligand-binding sensor domain. (357 aa) |
| | SGRA_4188 | Hypothetical protein; COG2971 Predicted N-acetylglucosamine kinase. (281 aa) |
