9 items (Saprospira grandis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Your Input:
	ndk	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
	gmk	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa)
	adk	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (192 aa)
	thiD	COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (253 aa)
	pyrH	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa)
	SGRA_2267	COG2035 Predicted membrane protein. (302 aa)
	thiL	Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (342 aa)
	ppk	Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (695 aa)
	cmk	COG0283 Cytidylate kinase. (237 aa)

Your Current Organism:

Saprospira grandis

NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
adk	gmk	SGRA_0637	SGRA_3886	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.720
adk	ndk	SGRA_0637	SGRA_3714	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.938
adk	pyrH	SGRA_0637	SGRA_1595	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.496
adk	thiL	SGRA_0637	SGRA_2362	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.	0.900
cmk	gmk	SGRA_3800	SGRA_3886	COG0283 Cytidylate kinase.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.484
cmk	ndk	SGRA_3800	SGRA_3714	COG0283 Cytidylate kinase.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.928
cmk	pyrH	SGRA_3800	SGRA_1595	COG0283 Cytidylate kinase.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.414
gmk	adk	SGRA_3886	SGRA_0637	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.720
gmk	cmk	SGRA_3886	SGRA_3800	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	COG0283 Cytidylate kinase.	0.484
gmk	ndk	SGRA_3886	SGRA_3714	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.925
gmk	pyrH	SGRA_3886	SGRA_1595	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.733
ndk	adk	SGRA_3714	SGRA_0637	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.938
ndk	cmk	SGRA_3714	SGRA_3800	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	COG0283 Cytidylate kinase.	0.928
ndk	gmk	SGRA_3714	SGRA_3886	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.925
ndk	pyrH	SGRA_3714	SGRA_1595	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.931
pyrH	adk	SGRA_1595	SGRA_0637	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.496
pyrH	cmk	SGRA_1595	SGRA_3800	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	COG0283 Cytidylate kinase.	0.414
pyrH	gmk	SGRA_1595	SGRA_3886	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.733
pyrH	ndk	SGRA_1595	SGRA_3714	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.931
thiL	adk	SGRA_2362	SGRA_0637	Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.900