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queE | Radical SAM family protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (255 aa) | ||||
SGRA_1066 | COG2324 Predicted membrane protein. (222 aa) | ||||
gadB | COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (483 aa) | ||||
speA | Orn/DAP/Arg decarboxylase 2; COG1166 Arginine decarboxylase (spermidine biosynthesis). (465 aa) | ||||
ribBA | Gtp cyclohydrolase ii; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (415 aa) | ||||
nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (227 aa) | ||||
ltaA | COG2008 Threonine aldolase. (338 aa) | ||||
ilvA | Pyridoxal-5'-phosphate-dependent protein beta subunit; COG1171 Threonine dehydratase. (319 aa) | ||||
hemB | COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (333 aa) | ||||
ptpS-2 | COG0720 6-pyruvoyl-tetrahydropterin synthase. (138 aa) | ||||
SGRA_3780 | Hypothetical protein. (766 aa) | ||||
mqnA | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (256 aa) | ||||
acnA | Aconitate hydratase; COG1048 Aconitase A. (759 aa) | ||||
purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (378 aa) | ||||
pabB | Chorismate binding protein; COG0147 Anthranilate/para-aminobenzoate synthases component I. (429 aa) | ||||
gmd | Putative GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (331 aa) | ||||
phrB-2 | COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (445 aa) | ||||
hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (342 aa) | ||||
dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa) | ||||
argH | COG0165 Argininosuccinate lyase. (445 aa) | ||||
psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (293 aa) | ||||
SGRA_3134 | Hypothetical protein; COG0804 Urea amidohydrolase (urease) alpha subunit. (490 aa) | ||||
folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (174 aa) | ||||
aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) | ||||
metC | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (379 aa) | ||||
ebsC | ybaK/ebsC protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (157 aa) | ||||
SGRA_2877 | Vitamin k-dependent gamma-carboxylase-like protein. (428 aa) | ||||
aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa) | ||||
SGRA_2545 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (413 aa) | ||||
cah | COG3338 Carbonic anhydrase. (281 aa) | ||||
SGRA_2370 | COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (485 aa) | ||||
aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (358 aa) | ||||
phhB | Transcriptional coactivator/pterin dehydratase; COG2154 Pterin-4a-carbinolamine dehydratase. (87 aa) | ||||
lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (413 aa) | ||||
mltD | COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). (600 aa) | ||||
mtnB | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (224 aa) | ||||
SGRA_2015 | Porphobilinogen deaminase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (221 aa) | ||||
ptpS | COG0720 6-pyruvoyl-tetrahydropterin synthase. (138 aa) | ||||
SGRA_2001 | Putative secreted protein containing cyclophilin type peptidyl-prolyl cis-trans isomerase domain; COG1413 FOG: HEAT repeat. (680 aa) | ||||
mqnD | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (273 aa) | ||||
SGRA_0693 | Hypothetical protein. (126 aa) | ||||
eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) | ||||
panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (115 aa) | ||||
pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa) | ||||
hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (340 aa) | ||||
nnrE | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] (517 aa) | ||||
SGRA_0460 | Vitamin K-dependent gamma-carboxylase. (434 aa) | ||||
dacA | Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (256 aa) | ||||
speE | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (399 aa) | ||||
mltG | Aminodeoxychorismate lyase family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (353 aa) | ||||
fbaB | COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes. (350 aa) | ||||
ubiD | UbiD family decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. (610 aa) | ||||
deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa) | ||||
SGRA_1751 | Hypothetical protein. (256 aa) | ||||
rfbB | COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (351 aa) | ||||
sdaA-2 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (482 aa) | ||||
hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (672 aa) | ||||
hemD | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (262 aa) | ||||
lpxC | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (461 aa) | ||||
fumC | Fumarate hydratase, class ii; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) | ||||
thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (623 aa) | ||||
SGRA_1434 | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (389 aa) | ||||
sdaA | COG1171 Threonine dehydratase. (301 aa) | ||||
fabZ | (3R)-hydroxymyristoyl-[acyl-carrier- protein]dehydratase; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases. (153 aa) | ||||
cynT | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (196 aa) | ||||
hutH | COG2986 Histidine ammonia-lyase. (500 aa) | ||||
SGRA_1374 | Hypothetical protein. (137 aa) | ||||
talA | Putative translaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa) | ||||
phrB | COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (466 aa) | ||||
mvaD | COG3407 Mevalonate pyrophosphate decarboxylase. (347 aa) | ||||
SGRA_1103 | Vitamin k-dependent gamma-carboxylase. (440 aa) |